Equine

Research Abstract

E20 - Serum Phosphorus, Magnesium, and Potassium Concentrations in Small Equids with Dyslipidemias

Thursday, June 14
5:00 PM - 5:15 PM
Location: WSCC 620

     Hypophosphatemia, hypokalemia, and hypomagnesemia are associated with various diseases in equids. Despite the interactions between these analytes and energy metabolism, evaluation of their concentrations in critically ill equids with lipid disorders is not frequently performed; therefore, the incidence of these abnormalities in these patients remains unclear. Medical records from 54 hospitalized small equids [ponies (multiple breeds), American Miniature Horses, and donkeys] greater than 2 years of age with serum triglyceride concentrations greater than 200 mg/dL admitted between 2002-2017 were reviewed, and relationships between biochemical analytes were assessed (Chi-square analysis).

     Most patients (59%) survived to discharge, while 41% were euthanized or died. Patients were stratified into quartiles based on triglyceride concentrations (1st quartile 207-343 mg/dL, 2nd quartile 386-638 mg/dL, 3rd quartile 668-989 mg/dL, and 4th quartile 1014-3281 mg/dL).  Equids with triglycerides in the 1st and 2nd quartiles were more likely to survive than those with triglyceride concentrations in the 3rd and 4th quartiles (OR = 1.66; p < 0.05). Hypophosphatemia (P < 2.5 mg/dL), hypokalemia (K < 3.0 mEq/L), and hypomagnesemia (total Mg < 1.29 mg/dL) were observed in 25%, 16.1%, and 10.7% of all cases, respectively. Only potassium concentration was significantly correlated with triglyceride concentrations (ρ = -0.318; p < 0.05). Equids with triglyceride concentrations in the 3rd and 4th quartiles were more likely to be hypokalemic (OR = 3.92; p < 0.05). Hypophosphatemia was not associated with survival, and most (72%) equids with hypertriglyceridemia and hypophosphatemia survived. Evaluation of phosphorus, potassium, and magnesium is recommended in equids with dyslipidemias.

Laura K. Dunbar, DVM, MS, DACVIM

Assistant Professor - Clinical
The Ohio State University College of Veterinary Medicine

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E20 - Serum Phosphorus, Magnesium, and Potassium Concentrations in Small Equids with Dyslipidemias

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