Obesity has become the most common health problem and can reduce longevity, increase risk of many chronic diseases, and adversely affect quality of life in dogs. Continuous caloric restriction (CCR) regimens have been applied for obesity treatment by creating a daily negative energy balance. However, CCR leads to decreased energy expenditure, which makes it difficult to continue to lose excess body fat and to maintain body weight after weight loss. The objective of this study was to compare the effect of CCR to an intermittent calorie restriction (ICR) regimen on body fat loss, and post-weight loss maintenance energy requirement (MERs) in obese dogs.
Thirty naturally obese dogs with BCS of 9 were randomized into two groups based on MERs, body weight, and % body fat. Dogs in the CCR group were fed 75% of their baseline MERs for 6 months, while the dogs in the ICR group were fed with the repeats of 75% baseline MERs for one week, and then 100% baseline MERs for one week for 6 months. Then, the caloric restriction in both groups was adjusted to 65% of baseline MERs for 2 additional months. ICR and CCR led to similar % body fat at the end of the study (35.40%± 1.38 vs 33.89% ± 1.52, p > 0.05). Dogs in the CCR group significantly (p = 0.0005) lowered their post-weight loss MERs by 17.92% compared with their baseline MERs. However, dogs in the ICR group numerically increased their post-weight loss MERs by 3.43% (p = 0.08).
Principal Research Scientist
Nestle Purina Research
Yuanlong Pan completed his BVM from Gansu Agricultural University, P.R. China. Dr. Pan received his PhD in Animal Nutrition from Virginia Tech, USA and PhD in Human Nutrition from University of North Carolina, USA. Dr. Pan conducted research in the area of nutrition and cognition at Wake Forest University School of Medicine from 1996 to 2000. In 2000, Dr. Pan joined Nestle Purina Research. At Nestle Purina, Dr. Pan has made significant advances in developing scientific knowledge that can be utilized to improve the health of dogs & cats in the areas of healthy aging, cognitive health, glucose management, and weight management. While he has had many discoveries, the most significant is in the area of nutrition and cognitive health. Dr. Pan’s research in this area focused on providing an additional energy source for the brain to compensate for the reduced ability to use glucose in aging pets and other neurological conditions including epilepsy management. In addition, Dr. Pan’s research focused on identifying and developing a blend of nutrients to support structure and function of the brain to promote healthy brain aging. Dr. Pan’s discovery research has advanced our knowledge in nutrition and cognitive health in mammals. Dr. Pan's research in weight management is now focusing on the effects of intermitttent caloric restriction on promoting healthy weight loss in pets.
Dr. Pan has published more than 20 papers, and obtained 78 patents. Dr. Pan has presented his research at many international meetings. In 2016, Dr. Pan won the Academy of Science-St Louis 2016 George Engelmann Interdisciplinary Award for his outstanding achievement in science through collaboration, and become a Fellow of the Academy of Science- St Louis.
Thursday, June 14
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