The incidence of acute kidney injury in hospitalized humans and dogs ranges from 14.6-22.7% and mild decreases in kidney function have marked effects on mortality, length of hospitalization and cost of treatment. The incidence of acute kidney injury in hospitalized horses is unreported.
The study aim was to apply a validated canine scoring system to assess the incidence of acute kidney injury in hospitalized horses. We hypothesized that the incidence of acute kidney injury in horses is similar to that reported in other species.
Clinical records from hospitalized adult horses, August 2015-October 2017, were reviewed. Horses must have been hospitalized for ≥3 days and had serum creatinine concentration measured twice. Horses that were diagnosed with primary renal pathology or were azotaemic on baseline serum biochemistry were excluded. A veterinary acute kidney injury scoring system was applied based on percentage increase in serum creatinine concentration from baseline: stage 0 ( < 150%), stage 1 (150-199% or ≥ 26.5 μmol/L), stage 2 (200-299%) or stage 3 ( ≥ 300%).
227 horses were included; 17.6% had an acute kidney injury (40/227). 16.7% were classified at stage 1 (38/227) and 0.9% as stage 2 (2/227). No horse had a stage 3 acute kidney injury.
The incidence of acute kidney injury in this population of hospitalized horses is similar to that reported in dogs and humans. Serum creatinine concentrations could be monitored in hospitalized horses to allow identification and early treatment of acute kidney injury. Further work is required to establish the impact of stage 1 acute kidney injury on long term equine health.
Resident in Equine Internal Medicine
Langford Equine Hospital/University of Bristol
Victoria graduated from the University of Liverpool, UK in 2013. She then spent a year in mixed practice before starting an equine medicine and critical care internship at Scone Equine Hospital, Australia. She then spent two years shuttling between Australia and the UK working as a stud veterinarian. Victoria started a residency in equine internal medicine at the University of Bristol in 2017.
Thursday, June 14
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