Poster Presentation

Poster Presentation

PR30 - The Effect of Endodontic Regeneration Medicaments on Microhardness and Surface Chemical Properties of Dentin

Thursday, April 26
10:00 AM - 1:00 PM
Room: Exhibit Hall

Introduction: Endodontic regeneration is an alternative to apexification in immature, necrotic teeth. Intracanal medicaments used for regeneration may affect dentin structure. Purpose: This study assessed the effects of calcium hydroxide and antibiotics on dentin microhardness and chemical structure. Materials and Methods: One hundred forty human dentin discs (4×6 mm) were cut from coronal root sections. The specimens were divided randomly into seven groups and covered with triple antibiotic paste (TAP), double antibiotic paste (DAP), ciprofloxacin, minocycline, metronidazole, calcium hydroxide (CH) or no medicament (control). After one and four weeks, Vicker's test measured hardness and the FTIR test calculated phosphate/amide I ratios. Data were subjected to one-way and two-way ANOVA and paired comparisons using Tukey’s post hoc test. Results: After one week, minocycline and TAP groups showed a significant reduction in microhardness compared to control.  After four weeks, CH and ciprofloxacin showed significant reductions in microhardness compared to one week exposure and control. Significant reductions in phosphate/amide I ratios occurred in all experimental groups except metronidazole, CH and DAP at one and four weeks compared to control. Conclusion: Dentin exposure to DAP and metronidazole for four weeks, and to CH for one week, had significantly less reduction in microhardness and superficial demineralization compared to TAP, ciprofloxacin and minocycline.

Omid Dianat

Endodontic Postgraduate Student
University of Maryland

Was born in Kashan, Iran in 1981. Finished dental school at 2005 in Shahid Beheshti University of Medical Sciences (Tehran, Iran) and graduated from Endodontic specialty from Isfahan University of Medical Sciences (Isfahan, Iran). He was formerly a full-time faculty member and an associate professor in Shahid Beheshti University of Medical sciences in Tehran, Iran and now the first year resident of Endodontic

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Mandana Naseri

Associate Professor
Shahid Beheshti University of Medical Sciences

Dr. Naseri is associate professor at endodontic department of Shahid Beheshti University, School of Dentistry and she was the former program director of Advanced Endodontic Specialty Program.

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Patricia A Tordik

Program Director, Advanced Specialty Education in Endodontics
University of Maryland

1986-1990 DMD, University of New Jersey, 1995-1997 Certificate, Endodontics, New York University, 2006-2008 Program Director, Naval Postgraduate Dental School, 2013-Present Professor and Program Director, Advanced Specialty Education in Endodontics, University of Maryland

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Farshid Gholami

Assistant professor
Zahedan University of Medical Sciences

Born in Iran, Finished Dental School and Advanced Endodontic Specialty program at Shahid Beheshti University of Medical Sciences and has started his new career as an assistant professor at endodontic department at Zahedan University of Medical Sciences in 2017

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PR30 - The Effect of Endodontic Regeneration Medicaments on Microhardness and Surface Chemical Properties of Dentin



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