Equine/Large Animal

Round Table Discussion: Regenerative Medicine: Stem Cell Regulations

Saturday, October 14
8:00 AM - 9:15 AM
Location: Room 302/303

Samuel P. Franklin, DVM, MS, PhD, DACVS-SA, DACVSMR

University of Georgia

Dr. Franklin completed his DVM at Colorado State University and his surgical residency and PhD at the University of Missouri and is a diplomate of the American College of Veterinary Surgeons and the American College of Veterinary Sports Medicine and Rehabilitation. After spending a year in private practice he became an assistant professor in small animal orthopedics and sports medicine at the University of Georgia 4 years ago. His recent and current research projects include assessment of biological therapies and tissue engineering strategies for treating osteoarthritis in dogs. Similarly, Dr. Franklin performs research evaluating the utility of MRI for assessing articular cartilage health in dogs with OA and cartilage defects. Additional areas of clinical and research interest include a focus on arthroscopy and minimally invasive surgical techniques.

Presentation(s):

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John Peroni, DVM, MS, DACVS-LA

Associate Professor of Surgery
University of Georgia

Dr. Peroni graduated from the College of Veterinary Medical Science at the University of Parma in Italy in 1994. During Veterinary School traveled to the U.S. and attended several institutions for prolonged periods of time including Delaware Equine Center, the University of Pennsylvania at New Bolton Center, Davis College of Veterinary Medicine and Chino Valley Equine Hospital. As a result of those experiences he was encouraged to pursue an internship at Chino Valley Equine Hospital where he remained for 2 years from ’94 to ‘96. He subsequently moved to Michigan State University where he completed a surgical residency and a MS degree from 1996 to 2000. Following this training he was fortunate to become a faculty member at the University of Georgia in the Fall of 2000 and is currently an Associate Professor with clinical, didactic and research responsibilities. Dr. Peroni’s research interests began with and still include the area of equine laminitis. The main focus of this interest has been the understanding of microvascular flow within the equine hoof capsule and the changes that occur to blood flow during the onset of laminitis. In the last 7 years, however, his research interest has shifted toward the development of animal models for the implementation of regenerative therapies aimed at the repair of musculoskeletal disorders primarily fracture repair. Two additional areas that have occupied much of his recent interest and efforts have been the study of (i) the anti-inflammatory and immunomodulatory effects of mesenchymal stem cells and (ii) the interaction between delivered cellular therapies and the host environment.

Presentation(s):

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Lauren V. Schnabel, DVM, PhD, DACVS-LA, DACVSMR-Equine

Assistant Professor of Equine Orthopedic Surgery
North Carolina State University

Dr. Lauren Schnabel, DVM, Ph.D., Diplomate ACVS-LA, and Diplomate ACVSMR-Equine is an assistant professor of orthopedic surgery at North Carolina State University.

Dr. Schnabel grew up in New York where she enjoyed spending time around both sport horses and racehorses. After receiving her bachelor degree from Duke University, she attended Cornell University for her veterinary degree. She then completed an internship at Rood and Riddle Equine Hospital before returning to Cornell as a postdoctoral fellow in the Laboratories of Dr. Lisa Fortier and Dr. Alan Nixon where she performed research on tendon and ligament repair. Dr. Schnabel completed her surgical residency at Cornell from 2006-2009 and became a Diplomate of the ACVS in 2010. She then completed her Ph.D. with Dr. Fortier on the immunologic properties of stem cells.

Dr. Schnabel began her position at NC State in 2013 working in both the equine hospital and her research laboratory. She specializes in the use of regenerative therapies for the treatment of musculoskeletal injuries and has published and given lectures both nationally and internationally on platelet-rich plasma, bone marrow aspirate concentrate, and stem cells. In particular, her laboratory is focused on understanding the immunologic and immunomodulatory properties of mesenchymal stem cells. Such knowledge is critical for potential allogeneic “off the shelf” stem cell therapy which would allow us to treat patients at the time of diagnosis rather than having to wait several weeks to months to culture stem cells from that patient. Her laboratory is also actively investigating the novel use of platelet-rich plasma lysate for the treatment of infectious arthritis in collaboration with Dr. Tom Schaer at Penn Vet.

At NC State, Dr. Schnabel runs the Clinical Mesenchymal Stem Cell Culture Service and is developing the Sports Medicine and Rehabilitation Service at with Dr. Rich Redding and colleagues.

Presentation(s):

Send Email for Lauren Schnabel

John Peroni, DVM, MS, DACVS-LA

Associate Professor of Surgery
University of Georgia

Dr. Peroni graduated from the College of Veterinary Medical Science at the University of Parma in Italy in 1994. During Veterinary School traveled to the U.S. and attended several institutions for prolonged periods of time including Delaware Equine Center, the University of Pennsylvania at New Bolton Center, Davis College of Veterinary Medicine and Chino Valley Equine Hospital. As a result of those experiences he was encouraged to pursue an internship at Chino Valley Equine Hospital where he remained for 2 years from ’94 to ‘96. He subsequently moved to Michigan State University where he completed a surgical residency and a MS degree from 1996 to 2000. Following this training he was fortunate to become a faculty member at the University of Georgia in the Fall of 2000 and is currently an Associate Professor with clinical, didactic and research responsibilities. Dr. Peroni’s research interests began with and still include the area of equine laminitis. The main focus of this interest has been the understanding of microvascular flow within the equine hoof capsule and the changes that occur to blood flow during the onset of laminitis. In the last 7 years, however, his research interest has shifted toward the development of animal models for the implementation of regenerative therapies aimed at the repair of musculoskeletal disorders primarily fracture repair. Two additional areas that have occupied much of his recent interest and efforts have been the study of (i) the anti-inflammatory and immunomodulatory effects of mesenchymal stem cells and (ii) the interaction between delivered cellular therapies and the host environment.

Presentation(s):

Send Email for John Peroni


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