Full Schedule
7:45 AM - 4:45 PMRegistration Open
- 8:30 AM - 4:30 PMSaturday Short CoursesShort Courses
8:30 AM - 4:30 PM3D Cell-Based Assays for Drug De-Risking Helena Hogberg – Center for Alternatives to Animal Testing (CAAT), Johns Hopkins Bloomberg School of Public Health ### 263597###Short Course Instructor - Funded @@@ Jens M. Kelm, PhD – InSphero AG ### 43392###Short Course Instructor - Funded @@@ Terry Riss – Promega Corporation ### 62431###Short Course Instructor - Funded
8:30 AM - 4:30 PMGetting Started with Excel & VBA in the Laboratory (2-Day) - LAPTOP REQUIRED Martin Echols, MS – EcholsTech ### 62409###Short Course Instructor - Funded @@@ William Neil – XLVBALAB ### 62427###Short Course Instructor - Funded
8:30 AM - 4:30 PMIntroduction to Laboratory Automation Steven Hamilton – SLAS ### 62416###Short Course Instructor - Not Funded @@@ James Gill – Bristol-Myers Squibb Company ### 62413###Short Course Instructor - Funded
8:30 AM - 4:30 PMLab-on-a-Chip: From Technology to Bioanalysis on Chip Sabeth Verpoorte, PhD – Groningen Research Institute of Pharmacy University of Groningen ### 62436###Short Course Instructor - Not Funded @@@ Johan Nilsson, PhD – Lund University ### 62429###Short Course Instructor - Funded @@@ Jorg P. Kutter, PhD, M.Sc. – University of Copenhagen ### 62423###Short Course Instructor - Funded
8:30 AM - 5:30 PMAssay Guidance Workshop for High Throughput Screening and Lead Discovery Nathan P. Coussens, PhD – National Center for Advancing Translational Sciences, National Institutes of Health ### 187865###Workshop Instructor @@@ Michelle Arkin – University of California, San Francisco ### 61294###Workshop Instructor @@@ Douglas Auld, PhD – Novartis ### 62440###Workshop Instructor @@@ Thomas D.Y Chung, PhD – Sanford Burnham ### 72744###Workshop Instructor @@@ Viswanath Devanarayan, PhD – AbbVie ### 286929###Workshop Instructor @@@ Terry Riss, Ph.D. – Promega Corporation ### 62431###Workshop Instructor @@@ G. Sitta Sittampalam, PhD – NIH/NCATS ### 119623###Workshop Faculty @@@ Menghang Xia ### 187863###Workshop Faculty @@@ Xin Xu ### 187864###Workshop Faculty
7:30 AM - 4:30 PMRegistration Open
- 8:30 AM - 4:30 PMSunday Short CoursesShort Courses
8:30 AM - 4:30 PMAffinity-based, Biophysical Methods for Screening and Mechanistic Studies: How to Effectively Use a Growing Biophysical Toolbox to Find and Characterize Chemical Leads Christine C. Genick, Dr. – Novartis ### 62412###Short Course Instructor - Funded @@@ Stefan Geschwindner – Discovery Sciences, AstraZeneca R&D Gothenburg ### 185943###Short Course Instructor - Funded
8:30 AM - 12:00 PMData Analytic Concepts for High Throughput Screening & Biomarker Applications (NEW!) Viswanath Devanarayan, PhD – AbbVie ### 286929###Short Course Instructor - Funded
8:30 AM - 4:30 PMData Management in the Age of Big Data, Mobile, and the Cloud Burkhard Schaefer – BSSN Software GmbH ### 62433###Short Course Instructor - Funded
8:30 AM - 4:30 PMDerivation, Maintenance, and Characterization Techniques for Human iPS Cells Used in Drug Discovery and Disease Modeling Kamal Garcha – GFY Biotech Consulting ### 187280###Short Course Instructor - Funded @@@ David J. Kahler, PhD PMP – NYU High Throughput Biology Laboratory ### 43236###Short Course Instructor - Funded
8:30 AM - 4:30 PMEstablishing Cell-Based Assays for Screening Terry Riss, Ph.D. – Promega Corporation ### 62431###Short Course Instructor - Funded @@@ Geoffrey Bartholomeusz, PhD – University of Texas MD Anderson Cancer Center ### 62406###Short Course Instructor - Not Funded @@@ Eric N. Johnson – Wuxi AppTec ### 185948###Short Course Instructor - Not Funded @@@ Lisa Minor, PhD – In Vitro Strategies, LLC ### 43412###Short Course Instructor - Funded
8:30 AM - 4:30 PMGetting Started with Excel & VBA in the Laboratory (2-Day) - LAPTOP REQUIRED William Neil – BMS ### 62427###Short Course Instructor - Funded @@@ Martin Echols – EcholsTech ### 62409###Short Course Instructor - Funded
8:30 AM - 4:30 PMHigh Content Screening: An Introduction to Instrumentation, Assay Development, Screening, Image and Data Analysis (NEW!) Steffen Jaensch – Janssen R&D, Pharmaceutical Companies of Johnson & Johnson ### 185946###Short Course Instructor - Funded @@@ Eberhard Krausz – VIB - Discovery Sciences ### 62422###Short Course Instructor - Funded
8:30 AM - 12:00 PMIntroduction to Flow Cytometry (NEW!)
John Nolan, PhD – Scintillon Institute ### 263599###Short Course Instructor - Funded @@@ J. Paul Robinson, PhD – Purdue University ### 263600###Short Course Instructor - FundedSponsored By:8:30 AM - 12:00 PMLead Generation: A Critical Discussion of Hypothesis & Empirical Strategies Jonathan Lee – Eli Lilly ### 185951###Short Course Instructor - Funded @@@ David C. Swinney, PhD – Institute for Rare and Neglected Diseases Drug Discovery ### 61363###Short Course Instructor - Funded
8:30 AM - 4:30 PMLiquid Handling Essentials (Interactive Course) Dana Campbell – Artel ### 72843###Short Course Instructor - Funded @@@ Nathaniel Hentz, PhD – NC State University - BTEC ### 43375###Short Course Instructor - Funded @@@ Lisa Knapp – Agilent Technologies ### 185950###Short Course Instructor - Funded
8:30 AM - 4:30 PMMulti parametric Analysis of High Content Screening Data (NEW!) - LAPTOP REQUIRED Marc Bickle, Dr. – MPI-CBG ### 61272###Short Course Instructor - Funded @@@ Antje Janosch – MPI-CBG ### 185947###Short Course Instructor - Funded
8:30 AM - 4:30 PMNext Generation Sequencing Technology Fundamentals and Applications Abizar Lakdawalla, PhD – Proxeom ### 187496###Short Course Instructor - Funded @@@ Dawei Lin, PhD – NIH/NIAID ### 62425###Short Course Instructor - Funded
8:30 AM - 4:30 PMPharmacology in Drug Discovery and Development: New Lives for Receptors as Drug Targets Through Allostery and Biased Signaling (NEW!) Terry Kenakin, PhD – UNC School of Medicine ### 62420###Short Course Instructor - Funded
8:30 AM - 4:30 PMSample Management: Best Practice, Trends and Challenges Susan Crimmin, Bsc PhD – Glaxo SmithKline ### 43275###Short Course Instructor - Funded @@@ Kathi E. Shea, BS – Brooks BioStorage Technologies ### 62434###Short Course Instructor - Funded
1:00 PM - 4:30 PMAdvanced Flow Cytometry (NEW!)
John Nolan – Scintillon Institute ### 263599###Short Course Instructor - Funded @@@ J. Paul Robinson, PhD – Purdue University ### 263600###Short Course Instructor - FundedSponsored By:1:00 PM - 4:30 PMAn Introduction to Mass Spectrometry and its Applications within Drug Discovery (NEW!) Jonathan Wingfield – AstraZeneca, Discovery Sciences ### 119486###Short Course Instructor - Not Funded @@@ Ian Sinclair, BSc – AstraZeneca, Discovery Sciences ### 272489###Short Course Instructor - Funded
12:00 PM - 5:00 PMSpeaker Ready Room
1:00 PM - 5:00 PMGene Editing for Drug Discovery John G. Doench – Broad Institute of MIT and Harvard ### 184220###Short Course Instructor - Funded @@@ Samuel A. Hasson, PhD – Pfizer, Inc. ### 185944###Short Course Instructor - Funded
7:30 AM - 6:00 PMRegistration Open
8:00 AM - 8:30 AMMorning Beverage Break
8:00 AM - 5:00 PMSpeaker Ready Room
8:00 AM - 6:15 PMCoat & Luggage Check
8:30 AM - 9:00 AMKeynote Session: Welcome and Opening Remarks
9:00 AM - 10:00 AMKeynote: Jennifer Lippincott-Schwartz; Group Leader, Howard Hughes Medical Institute’s Janelia Research Jennifer Lippincott-Schwartz – Howard Hughes Medical Institute's Janelia Research Campus ### 309320###Keynote Speaker
10:00 AM - 10:30 AMBeverage Break in the Exhibition Hall
10:00 AM - 12:00 PMPoster Setup
10:00 AM - 1:00 PMCareer Connections:
Mentoring Sessions / One-on-One Career Counseling Sessions / Job Boards in the SLAS Member Center10:00 AM - 6:00 PMExhibition Open
10:00 AM - 6:00 PMPoster Viewing in Exhibition Hall
- 10:30 AM - 12:30 PMAdvances in Genome Editing TechnologiesCellular Technologies
10:30 AM - 11:00 AMComparison of Cas9 activators in multiple species. Alejandro Chavez, MD/PhD – Wyss Institute at Harvard ### 286878###Speaker - Tony B. Awardee
11:00 AM - 11:30 AMGenome engineering with targeted recombinases Thomas Gaj – University of California, Berkeley ### 286917###Speaker - Funded
11:30 AM - 12:00 PMUsing engineered model organisms and high throughput screening tools to automate and scale the drug discovery process for rare genetic diseases Tom Hartl, PhD – Perlara, PBC ### 298514###Speaker - Not Funded
12:00 PM - 12:30 PMGenome ad Epigenome Editing with ZFNS and CRISPR Gregory Davis – MIlliporeSigma ### 283706###Session Chair & Speaker - No Funding
- 10:30 AM - 12:30 PMDigital and Droplet MicrofluidicsMicro- and Nanotechnologies
10:30 AM - 11:00 AMDrop Based Microfluidics and the Quantitative Biology Revolution Assaf Rotem – Harvard University ### 286955###Speaker - Funded
11:00 AM - 11:30 AMDroplet based functional assay for detecting protease secretion from circulating tumor cells Manjima Dhar – UCLA ### 286898###Speaker - Tony B. Awardee
11:30 AM - 12:00 PMRapid access to libraries of non-rule-of-five chemotypes via DNA-encoded solid-phase combinatorial synthesis Marie L. Malone – The Scripps Research Institute ### 286943###Speaker - Tony B. Awardee
12:00 PM - 12:30 PMStability of water-in-oil droplets as micro-reactors for ultrahigh-throughput droplet microfluidics applications Sindy KY. Tang – Stanford University ### 184225###Speaker - Funded
- 10:30 AM - 12:30 PMLabel Free Bioanalytical Techniques for Hit Identification and OptimisationAdvances in Bioanalytics, Biomarkers and Diagnostics
10:30 AM - 11:00 AMHigh-throughput MALDI TOF mass spectrometry for drug discovery in the ubiquitin system
Matthias Trost – MRC PPU, University of Dundee ### 286921###Speaker - FundedSponsored By:11:00 AM - 11:30 AMHigh throughput acoustic mass spectrometry: Development and delivery of a biochemical screen
Jonathan Wingfield – AstraZeneca, Discovery Sciences ### 119486###Speaker - Not FundedSponsored By:11:30 AM - 12:00 PMThe Use of Backscattering Interferometry to Study Compound Binding to GPCRs
Jonathan M. Ellery – Takeda Cambridge Ltd ### 286887###Speaker - FundedSponsored By:12:00 PM - 12:30 PMHigh Throughput Screening and Label-Free Characterization of Molecular Interactions Using a 32-spot Array
Klaus Wiehler – Sierra Sensors GmbH ### 286933###Speaker - Not FundedSponsored By:
- 10:30 AM - 12:30 PMLet There Be Light: Informatics Approaches to Exploring the Dark GenomeData Analysis and Informatics
10:30 AM - 11:00 AMIlluminating the Druggable Proteome Tudor I. Oprea, MD, PhD – UNM School of Medicine ### 286930###Speaker - Not Funded
11:00 AM - 11:30 AMOpen Targets Platform: mining gene-disease evidence for improved drug target selection Denise Carvalho-Silva – Open Targets - EMBL-EBI ### 286891###Speaker - Funded
11:30 AM - 12:00 PMDr. Gene Budger: A Web Application to Predict Drugs to Modulate the Expression of a Specific Gene Avi Maayan ### 289625###Speaker - Not Funded
12:00 PM - 12:30 PMGene-network based predictive modeling to identify biomarkers for high dimensional genomic data Viswanath Devanarayan, PhD – AbbVie ### 286929###Speaker - Funded
- 10:30 AM - 12:30 PMPhenotypic and High Content Screening AssaysAssay Development and Screening
10:30 AM - 11:00 AMKinetic Imaging of Calcium and Voltage Activity in hiPSC-Derived Dopaminergic Neurons Relevant to Parkinson’s Jeffrey Price, PhD – Vala Sciences ### 298517###Presenter
11:00 AM - 11:30 AMHigh-content imaging and single cell analysis for the systematic discovery and molecular dissection of novel pathways regulating nuclear architecture Gianluca Pegoraro – High-Throughput Imaging Facility/Center for Cancer Research/NCI/NIH ### 286893###Speaker - Not Funded
11:30 AM - 12:00 PMParsing cellular homogeneity from heterogeneous stem cell cultures Daniel Hoeppner – Lieber Institute ### 286957###Speaker - Not Funded
12:00 PM - 12:30 PMLight sheet microscopy for high content 3-D imaging of 3-D tissue cultures in a 96-well plate format Vincent Maioli – Imperial College London ### 318744###Speaker - Not Funded
- 10:30 AM - 12:30 PMScreening Automation: Modular vs. Highly integrated systemsAutomation and High-Throughput Technologies
10:30 AM - 11:00 AMDevelopment of Small Modular Systems to Enable New Scientific Applications Jason Matzen – The Genomics Institute of the Novartis Research Foundation ### 185954###Speaker - Not Funded
11:00 AM - 11:30 AMConnecting Hits to Leads through Fit-for-Purpose Automation Solutions Jonathan S. Lippy – Bristol Myers Squibb ### 286927###Speaker - Not Funded
11:30 AM - 12:00 PMModular, fully integrated or collaborative automation – what happens when you want it all ? Mark Wigglesworth – AstraZeneca - Discovery Sciences ### 119521###Speaker - Not Funded
12:00 PM - 12:30 PMIterative Design of an Automated Organism Foundry Jeff Z. Lou – Ginkgo Bioworks ### 286937###Speaker - Not Funded
- 12:30 PM - 1:15 PMExhibitor TutorialExhibitor Tutorial
12:30 PM - 1:15 PMBMG LABTECH Exhibitor Tutorial: How to Perform Real-Time, Walk-Away, Cell Health Assays Carl Peters – BMG LABTECH ### 45027###Exhibitor Tutorial Organizer @@@ Andrew Niles – Promega ### 308630###Exhibitor Tutorial Presenter @@@ Carl Peters – BMG LABTECH ### 45027###Exhibitor Tutorial Presenter
12:30 PM - 1:15 PMTitian Software Exhibitor Tutorial: Bristol-Myers Squibb, Titian Software, HighRes Biosolutions: A collaboration to implement seamless workflow management. Angela Cunniff ### 188225###Exhibitor Tutorial Organizer @@@ Jefferson Chin – Bristol-Myers Squibb ### 125019###Exhibitor Tutorial Presenter @@@ Anne Vergnon – Titian Software ### 125037###Exhibitor Tutorial Presenter @@@ Ira Hoffman – HighRes Biosolutions ### 309017###Exhibitor Tutorial Presenter
12:30 PM - 1:30 PMLunch in the Exhibition Hall Sponsored Drug Target Review
Sponsored By:- 12:30 PM - 1:45 PMExhibitor TutorialExhibitor Tutorial
12:30 PM - 1:45 PMBiosero Tutorial: Applications of Green Button Go Automation Scheduling Software for Small and Large Automation Platforms Kristen Macias ### 188232###Exhibitor Tutorial Organizer @@@ John Cesarek – Zymergen, Inc. ### 317167###Exhibitor Tutorial Presenter @@@ Harry Woodcock – Vertex Pharmaceuticals ### 318117###Exhibitor Tutorial Presenter
12:30 PM - 1:45 PMLabcyte Exhibitor Tutorial: Genomic Applications using the Labcyte Echo® Series of Liquid Handlers Pamela Lo ### 193058###Exhibitor Tutorial Organizer @@@ John Lesnick – Labcyte Inc ### 125074###Exhibitor Tutorial Presenter
12:30 PM - 1:45 PMMolecular Devices Exhibitor Tutorial: High-throughput analysis of complex 3D cell models, including iPSC-derived liver cells through new, automated techniques Caryn Tyler ### 188245###Exhibitor Tutorial Organizer @@@ Cathy Olsen, Ph.D – Molecular Devices ### 43417###Exhibitor Tutorial Presenter @@@ Grischa Chandy, Ph.D – Molecular Devices ### 196827###Exhibitor Tutorial Presenter @@@ Jayne Hesley – Molecular Devices LLC ### 72870###Exhibitor Tutorial Presenter @@@ Steve Wiltgen, Ph.D – Molecular Devices ### 318529###Exhibitor Tutorial Presenter
12:30 PM - 1:45 PMThermo Fisher Scientific Exhibitor Tutorial: Synthetic Biology Automation Christa Lamps ### 188845###Exhibitor Tutorial Organizer @@@ Huimin Zhao, Ph.D – University of Illinois, Urbana-Champaign (UIUC) ### 194011###Exhibitor Tutorial Presenter @@@ Ying-Jing Yuan ### 318188###Exhibitor Tutorial Presenter @@@ Hille Tekotte – University of Edinburgh ### 318189###Exhibitor Tutorial Presenter @@@ Axel Trefzer ### 318190###Exhibitor Tutorial Presenter
12:30 PM - 2:30 PMPerkinElmer Exhibitor Tutorial: An End-To-End 3D Cell Culture Workflow: Grow, Read, Decide Pam Clemens ### 186764###Exhibitor Tutorial Organizer
1:00 PM - 1:30 PMSLAS Author Services Info Session: Meet SLAS Technology Editor-in-Chief Edward Kai-Hua Chow of the National University of Singapore
1:00 PM - 2:00 PMCareer Connections
Mentoring 101 for Scientists Part I - Finding Mentors and Being the Best Mentee You Can Be; Joanne Kamens, Ph.D., Executive Director, Addgene1:00 PM - 3:00 PMPoster Presentations (Odd Numbered Posters)
1:30 PM - 2:00 PMSLAS Author Services Info Sessions: Using Kudos to Get More People to Read and Cite Your Research Beth Berry of SAGE Publishing
2:00 PM - 2:30 PMSLAS Author Services Info Sessions: Accelerate Life Sciences Research with Atypon Literatum Beth Berry of SAGE Publishing
- 2:00 PM - 2:45 PMExhibitor TutorialExhibitor Tutorial
2:00 PM - 2:45 PMGenedata Screener for SPR: An Efficient Solution for Small and Large Molecule Screening Analysis Workflows Michaela Kraus ### 289622###Exhibitor Tutorial Organizer @@@ Spencer Carson – Genedata Inc. ### 308968###Exhibitor Tutorial Presenter
2:00 PM - 2:45 PMIntelliCyt Exhibitor Tutorial: Phenotypic Screening Realized. Breaking new ground in suspension cell screening with the IntelliCyt platform Joe Zock – IntelliCyt Corporation ### 297577###Exhibitor Tutorial Organizer @@@ Dave Gephard, MS – Pfizer ### 311369###Exhibitor Tutorial Presenter @@@ Catherine Bardelle, PhD – AztraZeneca UK ### 311370###Exhibitor Tutorial Presenter
2:00 PM - 2:45 PMLab Services B.V. Exhibitor Tutorial: Automated Platform & Method Design; Optimized by Simulation Ir. Ferry de Vugt – Lab Services ### 316792###Exhibitor Tutorial Organizer @@@ Ir. Ferry de Vugt – Lab Services bv ### 319094###Exhibitor Tutorial Presenter
2:00 PM - 2:45 PMLumigen Exhibitor Tutorial: A High Throughput Immunoassay Application: Monoclonal Antibody Screening Kristen Pauly ### 190682###Exhibitor Tutorial Organizer
2:00 PM - 2:45 PMMultispan Exhibitor Tutorial: Striking a balance between physiologically relevant GPCR Assays and suitability for screening Alex Batchelor – Multispan, Inc. ### 43293###Exhibitor Tutorial Organizer @@@ Lisa Minor, Ph.D – Multispan, Inc. ### 187995###Exhibitor Tutorial Presenter
2:00 PM - 2:45 PMParker Hannifin Exhibitor Tutorial: How automated cell analysis and selection creates standardization in the differentiation and expansion process Brian Handerhan – Parker Hannifin ### 302803###Exhibitor Tutorial Organizer @@@ George F. Muschler, MD – Cleveland Clinic, Lerner Research Institute ### 318229###Exhibitor Tutorial Presenter
2:00 PM - 2:45 PMTakara Bio, Inc. Exhibitor Tutorial: Efficient, footprint-free gene editing of iPS cells using CRISPR/Cas9 for disease modeling and drug screening applications Liz Quinn, PhD – Takara Bio USA, Inc. ### 317278###Exhibitor Tutorial Organizer
2:00 PM - 2:45 PMThermo Fisher Scientific Exhibitor Tutorial: New fully automated system for nucleic acid and protein purification Christa Lamps ### 188845###Exhibitor Tutorial Organizer @@@ Xingwang Fang, PhD – ThermoFisher Scientific ### 318191###Exhibitor Tutorial Presenter
2:00 PM - 5:00 PMCareer Connections:
Mentoring Sessions / One-on-One Career Counseling Sessions / Job Boards in the SLAS Member Center2:30 PM - 3:00 PMBeverage Break in the Exhibition Hall
- 3:00 PM - 5:00 PMBiochemical and Biophysical ScreeningAssay Development and Screening
3:00 PM - 3:30 PMUse of Biophysical Technologies to Identify and Characterize Hit Compounds for NR3A Subunit of NMDA Receptors Chen-Ting Ma – Sanford Burnham Prebys Medical Discovery Institute ### 286950###Speaker - Funded
3:30 PM - 4:00 PMAnalysis of bispecific interactions with the switchSENSE biosensor Ulrich Rant – Dynamic Biosensors GmbH ### 72743###Speaker - Not Funded
4:00 PM - 4:30 PMTargeting Structurally and Functionally Diverse Nucleic Acids with Druglike Small Molecules John S. Schneekloth, Jr. – Chemical Biology Laboratory, National Cancer Institute ### 286904###Speaker - Not Funded
4:30 PM - 5:00 PMUnlocking the RNA target space: In search for selective small molecule RNA binders Razvan Nutiu – NIBR ### 283717###Session Chair & Speaker - No Funding
- 3:00 PM - 5:00 PMDevelopment of Cellular Models for Phenotypic ScreeningCellular Technologies
3:00 PM - 3:30 PMSystematic validation of disease-specific genetic association data in cellular models Joel A. Klappenbach – Merck & Co., Inc. ### 286899###Session Chair & Speaker - No Funding
3:30 PM - 4:00 PMCalibrating human adipocyte assays for type 2 diabetes target validation Amit Majithia – Broad Institute/ Massachusetts general hospital ### 286934###Speaker - Funded
4:00 PM - 4:30 PMDeveloping assay technologies to realize the potential of iPSC technology in drug discovery Han Xu – Amgen Inc ### 286931###Speaker - Not Funded
4:30 PM - 5:00 PMToward primary drug screening using iPSC-derived human motor neurons in 1536-well plates Zhong-Wei Du, PhD – BrainXell, Inc. ### 286941###Speaker - Not Funded
- 3:00 PM - 5:00 PMHigh Content and High Throughput AutomationAutomation and High-Throughput Technologies
3:00 PM - 3:30 PMPast, present & future – AstraZeneca’s experience, learning and vision in the delivery of automated High Content Screening Paul Harper – AstraZeneca ### 286936###Speaker - Not Funded
3:30 PM - 4:00 PMMultiplexed Live Cell Phenotypic Screening: Cell level vs Multi-variant Well Level Analysis James LaRocque – AMRI ### 286907###Speaker - Not Funded
4:00 PM - 4:30 PMThe European Lead Factory: an efficient open-innovation platform with unique screening capabilities Steven van Helden – Pivot Park Screening Centre ### 78012###Speaker - Not Funded
4:30 PM - 5:00 PMApp Store and High Performance Computing for High Content Screening Seungtaek Lee – PerkinElmer ### 286953###Speaker - Not Funded
- 3:00 PM - 5:00 PMPerspectives on Commercialization of Integrated Micro and Nanofluidic DevicesMicro- and Nanotechnologies
3:00 PM - 3:30 PM2017 SLAS Innovation Award Top 10 Finalist – Optimizing Clinical Combination Therapy Using a Phenotypic Personalized Medicine Technology Platform Dean Ho, Ph.D. – UCLA Bioengineering and The Weintraub Center ### 286896###Speaker - Not Funded
3:30 PM - 4:00 PM2017 SLAS Innovation Award Top 10 Finalist – Transcriptional profiling of single cells using droplet microfluidics Tobias Wheeler – 10X Genomics ### 286894###Speaker - Not Funded
4:00 PM - 4:30 PMMicrofluidics without Borders: Commercialization Perspectives of High Throughput Applications for Acoustic Droplet Ejection Technology Sammy Datwani – Labcyte Inc. ### 43354###Session Chair & Speaker - WITH Funding
4:30 PM - 5:00 PM2017 SLAS Innovation Award Top 10 Finalist – Vortex Biosciences technology for fast and label-free isolation of circulating tumor cells from blood samples Elodie Sollier-Christen – Vortex Biosciences, Inc. ### 286889###Speaker - Funded
- 3:00 PM - 5:00 PMTargeted Biomarker AnalysisAdvances in Bioanalytics, Biomarkers and Diagnostics
3:00 PM - 3:30 PMEffect of Controlled Diet on Biomarker Measurements in the Clinic
Petia Shipkova – Bristol-Myers Squibb ### 286959###Speaker - Not FundedSponsored By:3:30 PM - 4:00 PMThe SOMAscan® assay and SOMAmer® reagents: Translatable tools from high-throughput biomarker discovery to targeted assays
Sheri K. Wilcox – SomaLogic, Inc. ### 286911###Speaker - Not FundedSponsored By:4:00 PM - 4:30 PM2017 SLAS Innovation Award Top 10 Finalist – Inkjet printing technology for facilitated at will antimicrobial susceptibility testing (FAST) in under 5 hours: addressing the needs of a so-called 'post-antibiotic era'.
James E. Kirby, MD – Beth Israel Deaconess Medical Center and Harvard Medical School ### 286912###Speaker - Not FundedSponsored By:4:30 PM - 5:00 PMEarwax: A Neglected Body Secretion or a Step Ahead in Clinical Diagnosis!
Engy Shokry. Shokry, Masters and PhD of Pharmaceutical Sciences, Postdoctoral fellow in Meyer Children Hospital (Italy) – Laboratory of Methods of Extraction and Separation, Institute of Chemistry, Federal University of Goias (LAMES-IQ-UFG) (Laboratório de Métodos de Extração e Separação, Instituto de Química, Universidade Federal de Goiás ) ### 286916###Speaker - Tony B. AwardeeSponsored By:
- 3:00 PM - 5:00 PMThe Challenges and Benefits of CollaborationData Analysis and Informatics
3:00 PM - 3:30 PMHow Can Informatics Systems Help External Collaborations Succeed?
Robert D. Brown – Dotmatics Inc ### 286888###Speaker - Not FundedSponsored By:3:30 PM - 4:00 PM'Virtual' R&D in Pharma: What are the Virtues (and Vices)?
Steven Wesolowski – Xenon Pharmaceuticals ### 286965###Speaker - FundedSponsored By4:00 PM - 4:30 PMHow to solve the logistical challenges of collaborating to enable efficient access to innovation and expertise.
Elizabeth Iorns, PhD – Science Exchange ### 119548###Speaker - Not FundedSponsored By4:30 PM - 5:00 PMUtilizing Cloud Technology to Solve Challenges in Modern Laboratories
Marc A. Daxer – Fraunhofer Institute for Manufacturing Engineering and Automation IPA ### 286923###Speaker - Tony B. AwardeeSponsored By
5:00 PM - 5:15 PMStudent Poster Award Winner Announcement
5:00 PM - 6:00 PMReception in Exhibition Hall Celebrating the 2016 SLAS Journal Achievement Award Honorees
5:00 PM - 6:00 PMStudent and Early Career Professionals Mixer
5:00 PM - 6:00 PMThe Lab Man Podcast - The Lab Man Interviews the Student Poster Winners
- 6:00 PM - 8:00 PMLate Night with LRIG - Rapid-Fire Innovation SessionLate Night with LRIG
6:00 PM - 6:40 PMinfinitesimal's New Single Cell Transfection System Jonathon J. Prinz – infinitesimal LLC ### 323055###Exhibitor Tutorial Speaker
6:00 PM - 6:40 PMLabel-Free Ultra-High Throughput Screening by MALDI Mass Spectrometry: One Million Samples per Week Jens Fuchser – Bruker Daltonics ### 315725###Exhibitor Tutorial Speaker
6:00 PM - 6:40 PMLionheart FX Automated Live Cell Imager Caleb Foster – BioTek Instruments, Inc. ### 316927###Exhibitor Tutorial Speaker
6:00 PM - 6:40 PMMicro Dispense – New Precision in Liquid Handling Thomas P. Weisener, Dr. – HNP Mikrosysteme GmbH ### 314733###Exhibitor Tutorial Speaker
6:00 PM - 6:40 PMNanotech Biomachines, Inc. (Nanotech Bio): The Rise of Bioelectronic Lead Discovery Will Martinez – Nanotech Biomachines, Inc. ### 316243###Exhibitor Tutorial Speaker
6:00 PM - 6:40 PMNot All Cell Lines Are Created Equal - Impact of Surface Expression on GPCR Assays Alex Batchelor – Multispan, Inc. ### 43293###Exhibitor Tutorial Speaker
6:40 PM - 7:20 PMAcouTrap: Trapping and enriching cells, bacteria and extracellular vesicles using ultrasound Torsten Freltoft, MSc, PhD – AcouSort AB ### 315726###Exhibitor Tutorial Speaker
6:40 PM - 7:20 PMAssay Development into HTS: Redefining Reagent Dispensing Joby Jenkins – TTP Labtech ### 43277###Exhibitor Tutorial Speaker
6:40 PM - 7:20 PMCreoptix WAVE - Kinetics at High Sensitivity and with Crude Samples Matyas Vegh – Creoptix ### 315724###Exhibitor Tutorial Speaker
6:40 PM - 7:20 PMQuantitative Immunoassays in 10 minutes Claudio Rhyner – Davos Diagnostics AG ### 315727###Exhibitor Tutorial Speaker
6:40 PM - 7:20 PMIntroducing the latest advance for iQue Screener PLUS: Fast is now even more “EXCITING”! Joseph Zock – IntelliCyt Corporation ### 316926###Exhibitor Tutorial Speaker
6:40 PM - 7:20 PMBioDep - An Entirely New Bio-Coating Technology Liam O'Neill, PhD – Theradep Technologies ### 316245###Exhibitor Tutorial Speaker
7:25 PM - 8:00 PMA New Device for Rapid Ultrasensitive Drug Binding Measurements Brett Goldsmith – Nanomedical Diagnostics ### 315723###Exhibitor Tutorial Speaker
7:25 PM - 8:00 PMDirect Mark ID Technology Jeff Denton – Computype ### 314734###Exhibitor Tutorial Speaker
7:25 PM - 8:00 PMIntroduction to MIP Diagnostics Ltd. - "Plastic antibodies" Francesco Canfarotta – MIP Diagnostics Limited ### 316242###Exhibitor Tutorial Speaker
7:25 PM - 8:00 PMRevolutionary Compound Distribution Workstation - Flex Swile Ed Halpin – Chemspeed Technologies Inc. ### 298543###Exhibitor Tutorial Speaker
7:25 PM - 8:00 PMUpcyte - Expanded Primary Cells Astrid Nörenberg, PhD – upcyte technologies GmbH ### 188032###Exhibitor Tutorial Speaker
6:30 PM - 8:30 PMSLAS Student and Early Career Professionals Event at Lucky Strike
7:15 AM - 9:00 AMAnalytical, Life Science and Diagnostic Association Special Session (ALDA) (Invitation Only)
7:30 AM - 8:30 AMCareer Connections
Grants Process and Funding Opportunities from the National Institutes of Health (NIH); Daniel Gossett, Ph.D., Program Director, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)7:30 AM - 6:00 PMRegistration Open
7:45 AM - 8:00 AMMorning Beverage Break
- 8:00 AM - 9:15 AMSpecial Interest Group (SIG)Special Interest Group (SIG)
8:00 AM - 9:15 AMHCS/HCA Data and Informatics Special Interest Group (SIG)
Paul A. Johnston – Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh ### 62456###SIG Chair @@@ Joe Trask – PerkinElmer ### 308266###SIG Speaker - Not Funded @@@ Carrie Lovitt, PhD – Griffith University (Nathan Campus), Queensland, Australia. ### 308267###SIG Speaker - Not Funded @@@ Dan LaBarbera, PhD – University of Colorado, AMC. ### 308268###SIG Speaker - FundedSponsored By:8:00 AM - 9:15 AMSample Management Special Interest Group (SIG) Sue Holland-Crimmin ### 263598###SIG Chair @@@ Rosalia Gonzales ### 319122###SIG Speaker - Not Funded @@@ Mary Beth Burton ### 319123###SIG Speaker - Not Funded
8:00 AM - 9:15 AMScreen Design and Assay Technology Special Interest Group (SIG) Kenda Evans ### 302253###SIG Chair @@@ James R. Beasley, PhD – Venenum Biodesign ### 43329###SIG Chair @@@ Mary Jo Wildey – Merck Research Labs ### 199109###SIG Speaker - Not Funded @@@ Adam Weinglass ### 319547###SIG Speaker - Not Funded
8:00 AM - 9:15 AMStem Cells and 3D Microtissues Special Interest Group (SIG)
Marcie Glicksman, PhD – Orig3n, Inc Boston, MA, USA ### 62448###SIG Chair @@@ G. Sitta Sittampalam, PhD – NIH/NCATS ### 119623###SIG Chair @@@ Lucie Low, PhD – NCATS/NIH ### 333157###SIG Speaker - Not Funded @@@ Michael J. Werner, DC – Executive Director/Co-Founder, Alliance for Regenerative Medicine ### 333598###SIG Speaker - FundedSponsored By:8:00 AM - 9:15 AMTechnology Transfer and CRO/CMO Project Management Special Interest Group (SIG) Raymond Price, PhD – DiscoverX ### 140376###SIG Chair and Speaker - Funded
8:00 AM - 5:00 PMSpeaker Ready Room
8:00 AM - 6:15 PMCoat & Luggage Check
- 9:30 AM - 10:15 AMExhibitor TutorialExhibitor Tutorial
9:30 AM - 10:15 AMBMG LABTECH Exhibitor Tutorial: High-throughput solutions for screening cellular metabolic activity and mitochondrial toxicity Carl Peters – BMG LABTECH ### 45027###Exhibitor Tutorial Organizer @@@ Catherine Wark – BMG LABTECH ### 199127###Exhibitor Tutorial Presenter @@@ Dave Hoffman – Cayman Chemical ### 309203###Exhibitor Tutorial Presenter
9:30 AM - 10:15 AMCorning Life Sciences Exhibitor Tutorial: 3-Dimensional Cell Culture Systems, Novel Technologies, and Their Use at the Laboratory Bench Nicole Athanas ### 299608###Exhibitor Tutorial Organizer @@@ Mark Rothenberg, PhD – Corning Inc. ### 43426###Exhibitor Tutorial Presenter @@@ Tim Spicer, Co-Chair 2018 – The Scripps Reseacrh Institute, Scripps Florida ### 119624###Exhibitor Tutorial Presenter
9:30 AM - 10:15 AMGenedata Exhibitor Tutorial: Effortlessly scale up automated patch clamp research with Genedata Screener Michaela Kraus ### 289622###Exhibitor Tutorial Organizer @@@ Stephan Steigele – Genedata AG ### 196528###Exhibitor Tutorial Presenter
9:30 AM - 10:15 AMBruker Daltonics Exhibitor Tutorial: Accelerating High Throughput Screening with Bruker MALDI Mass Spec Nancy Salt ### 300994###Exhibitor Tutorial Organizer @@@ Swen Tyrasa – Analytik Jena ### 311217###Exhibitor Tutorial Presenter @@@ Melanie Leveridge – GlaxoSmithKline, Stevenage UK ### 184211###Exhibitor Tutorial Presenter
9:30 AM - 10:15 AMLumigen Exhibitor Tutorial: Making Immunoassay Development, Validations and Sample Analysis Fast, Easy and Cost-Effective Presented by Beckman Coulter Lumigen and Thermo Fisher Scientificâ„¢ Kristen Pauly ### 190682###Exhibitor Tutorial Organizer @@@ Mark J. Cameron – Beckman Coulter ### 125027###Exhibitor Tutorial Presenter @@@ Adyary Fallarero, PhD – Thermo Fisher Scientific, Finland ### 308356###Exhibitor Tutorial Presenter
9:30 AM - 10:15 AMPerkinElmer Exhibitor Tutorial: The benefits of Alpha SureFire Ultra assay sensitivity and modularity: Singleplex and Multiplex protein phosphorylation quantification in relevant cellular models and functional activity measurement in antibodies Pam Clemens ### 186764###Exhibitor Tutorial Organizer
9:30 AM - 10:15 AMAutomation powered by Genera, true dynamic scheduler and integration framework applied to different lifesciense applications. Elizabeth Rodziewicz – Retisoft, Inc. ### 317409###Exhibitor Tutorial Organizer @@@ Lauren Alcoser – BASF ### 333594###Exhibitor Tutorial Presenter @@@ Marcin Paduch – Recombinant Antibody Network, The University of Chicago ### 61303###Exhibitor Tutorial Presenter
9:30 AM - 12:30 PMCareer Connections:
Mentoring Sessions / One-on-One Career Counseling Sessions / Job Boards in the SLAS Member Center9:30 AM - 6:00 PMExhibition Open
9:30 AM - 6:00 PMPoster Viewing in Exhibition Hall
10:00 AM - 10:30 AMBeverage Break in the Exhibition Hall
10:00 AM - 11:00 AMThe Lab Man Podcast - The Lab Man Interviews SLAS Discovery Editor-in-Chief Robert M. Campbell, PhD (Eli Lilly & Co.) and SLAS Technology Editor-in-Chief Edward Kai-Hua Chow, PhD (National University of Singapore)
- 10:30 AM - 12:30 PMAssay Platforms for BiologicsAssay Development and Screening
10:30 AM - 11:00 AMDiscovering Antibodies to a Moving Target Caroline S. Colley – MedImmune ### 119571###Speaker - Not Funded
11:00 AM - 11:30 AMDeveloping an Assay Platform for Screening and Characterisation of Antibody Drug Conjugates Rachel A E Forfar, PhD – MRC Technology ### 294693###Speaker - Not Funded
11:30 AM - 12:00 PM2017 SLAS Innovation Award Top 10 Finalist – Automated 3D Cell Culture Platform for Investigating Chemoresistance and Efficacy of Antibody-based Therapeutics Christopher Millan – CellSpring AG ### 286897###Speaker - Not Funded
12:00 PM - 12:30 PMEvaluation of protein adsorption from peptides to antibodies to laboratory consumables Peter Rezk – Wheaton Industries ### 286939###Speaker - Not Funded
- 10:30 AM - 12:30 PMAutomating Phenotypic and Target Based Discovery using Parallel Automated ApproachesAutomation and High-Throughput Technologies
10:30 AM - 11:00 AMMultiplexed Human Cell Based Assays for Medium Throughput Screening Robin A. Felder, PhD – The University of Virginia ### 184282###Session Chair & Speaker - WITH Funding
11:00 AM - 11:30 AM3D Shaped Cell Microcarriers for Cell Culture, Manipulation, High-throughput Analysis, and Sorting of Adherent Cells Chueh-Yu Wu – University of California, Los Angeles ### 286900###Speaker - Tony B. Awardee
11:30 AM - 12:00 PMPhenotypic Screening to identify modulators of immune cell effector functions Renate H. Schnitzer – Boehringer Ingelheim RCV ### 286903###Speaker - Not Funded
12:00 PM - 12:30 PM2017 SLAS Innovation Award Top 10 Finalist – Spheroid microarrays to rapidly screen spheroid morphology and protein expression for regenerative medicine, toxicology and cancer research Delyan P. Ivanov – University of Nottingham ### 286919###Speaker - Not Funded
- 10:30 AM - 12:30 PMEnhancing Scientific Reproducibility and Reuse Through Better Workflow and Data TechnologiesData Analysis and Informatics
10:30 AM - 11:00 AMStanding up for the quality of our data: A voluntary commitment to research quality assurance. Rebecca L. Davies, PhD – University of Minnesota College of Veterinary Medicine ### 286951###Speaker - Funded
11:00 AM - 11:30 AMCloud-based design and data analytics for reproducible, reusable science Timothy S. Gardner – Riffyn ### 286920###Session Chair & Speaker - WITH Funding
11:30 AM - 12:00 PMDigitizing Discovery Lab Workflow Viral Vyas – Bristol Myers Squibb ### 286879###Speaker - Not Funded
12:00 PM - 12:30 PMToward quality management in cancer proteomics Christopher R. Kinsinger – National Cancer Institute ### 286958###Speaker - Not Funded
- 10:30 AM - 12:30 PMGenetic Screens for Target Discovery and ValidationCellular Technologies
10:30 AM - 11:00 AMTherapy of Lymphoma Inspired by Functional and Structural Genomics Louis Staudt – National Cancer Institute ### 286949###Session Chair & Speaker - No Funding
11:00 AM - 11:30 AMPooled genome-wide screens as a powerful tool for discovering drug resistance genes in cancer Federica Piccioni – Broad Institute of MIT and Harvard ### 286913###Speaker - Not Funded
11:30 AM - 12:00 PMTarget Devalidation by CRISPR/Cas9 Technology Lorenz M. Mayr – AstraZeneca ### 61296###Speaker - Not Funded
12:00 PM - 12:30 PMHigh resolution CRISPR screens for mapping the human essentialome Jason Moffat ### 284610###Speaker - Funded
- 10:30 AM - 12:30 PMSingle Cell AnalysesMicro- and Nanotechnologies
10:30 AM - 11:00 AMPrecision Immunology Through Deeper, Single Cell Profiling Pratip K. Chattopadhyay, PhD – Precision Medicine Incubator, Vaccine Research Center, NIH ### 286971###Speaker - Not Funded
11:00 AM - 11:30 AM2017 SLAS Innovation Award Top 10 Finalist – A High Throughput Technology for the Isolation of Single Cells Using a Nanoliter Dispenser Michael Klinger – Fraunhofer Institute for Manufacturing Engineering and Automation IPA, Stuttgart, Germany ### 286922###Speaker - Tony B. Awardee
11:30 AM - 12:00 PMOpen the Doors of Perception: Reproducible data reduction and deep learning bring diagnostic intra-sample comparison to n-dimensional single cell data from cytometry and single cell sequencing. Michael D. Stadnisky, Ph.D. – FlowJo, LLC ### 119491###Speaker - Not Funded
12:00 PM - 12:30 PMNovel method to dissociate solid tumors into viable single cells using Bulk Lateral Ultrasonic energy Daniel C. Holley, PhD – Microsonic Systems Inc. ### 286928###Speaker - Not Funded
- 10:30 AM - 12:30 PMTarget Identification After Phenotypic ScreeningAdvances in Bioanalytics, Biomarkers and Diagnostics
10:30 AM - 11:00 AMStrategies and technologies to identify targets from phenotypic screens by quantitative proteomics
Dirk Ullmann – Evotec AG ### 61325###Speaker - Not FundedSponsored By:11:00 AM - 11:30 AMDeconvolution of Targets for Small Molecules Using a Palladium-Cleavable Capture Tag
Rachel Friedman Ohana – Promega corporation ### 286910###Speaker - Not FundedSponsored By:11:30 AM - 12:00 PMUnravelling the target and novel MOA of a tuberculosis phenotypic hit
Chun-Wa Chung – GSK, Hertfordshire, UK ### 185939###Speaker - Not FundedSponsored By:12:00 PM - 12:30 PMDiscovery of the NLRP3 inflammasome inhibitor CP-456,773 (CRID3) through phenotypic screening
Fabien Vincent – Pfizer ### 119517###Session Chair & Speaker - No FundingSponsored By:
- 12:30 PM - 1:15 PMExhibitor TutorialExhibitor Tutorial
12:30 PM - 1:15 PMAgilent Exhibitor Tutorial: An Automation Solution for NGS Library Prep in a Growing Molecular Genetics Lab David Hatfield ### 286639###Exhibitor Tutorial Organizer
12:30 PM - 1:15 PMArtel Exhibitor Tutorial: Best Practices for Equipment Calibration and Analytical Controls in the Diagnostics Laboratory Kerry Fairlie – Artel ### 193536###Exhibitor Tutorial Organizer @@@ George W. Rodrigues, PhD – Artel ### 134481###Exhibitor Tutorial Presenter @@@ Rebecca Butler – CareDx, Inc. ### 309001###Exhibitor Tutorial Presenter
12:30 PM - 1:15 PMBeckman Coulter Exhibitor Tutorial: Advances in Cellular Automation Donna Gorman ### 184709###Exhibitor Tutorial Organizer @@@ Michael Kowalski, PhD – Beckman Coulter Life Sciences ### 308330###Exhibitor Tutorial Presenter
12:30 PM - 1:15 PMBiodesy Exhibitor Tutorial: Biodesy Delta: Screening with Structural Insight Heather Meeks ### 284939###Exhibitor Tutorial Organizer @@@ John Quinn – Genentech ### 318620###Exhibitor Tutorial Presenter @@@ Pascal Fortin – Relay Therapeutics ### 318621###Exhibitor Tutorial Presenter
12:30 PM - 1:15 PMBMG LABTECH Exhibitor Tutorial: Real Time Detection of G-protein Coupled Receptors in Living Cells Carl Peters – BMG LABTECH ### 45027###Exhibitor Tutorial Organizer @@@ Shane E. Tillo, PhD – Montana Molecular ### 188037###Exhibitor Tutorial Presenter @@@ EJ Dell – BMG LABTECH ### 45024###Exhibitor Tutorial Presenter
12:30 PM - 1:15 PMFesto Exhibitor Tutorial: Make vs. buy - Choosing automated pipetting options Andrea Leuschner ### 293272###Exhibitor Tutorial Organizer @@@ Sam Stoney – Festo Corporation ### 309022###Exhibitor Tutorial Presenter
12:30 PM - 1:15 PMTranscriptic Exhibitor Tutorial: AbbVie's creation of the virtual pharma through Transcriptic's robotic cloud lab platform Taylor Murphy ### 194970###Exhibitor Tutorial Organizer @@@ Lisa Hazelwood – AbbVie ### 308804###Exhibitor Tutorial Presenter
12:30 PM - 1:30 PMLunch in the Exhibition Hall Sponsored by SelectScience
Sponsored By: SelectScience- 12:30 PM - 1:45 PMExhibitor TutorialExhibitor Tutorial
12:30 PM - 1:45 PMIntelliCyt Exhibitor Tutorial: Rethink Possible: Phenotypic and Functional Screening in Immunology and Beyond with the IntelliCyt platform Joe Zock – IntelliCyt Corporation ### 297577###Exhibitor Tutorial Organizer @@@ Stefan Frisbutter, PhD – DGFZ ### 308992###Exhibitor Tutorial Presenter @@@ Aaron Wilson, PhD – Novartis Institutes for Biomedical Research ### 308994###Exhibitor Tutorial Presenter @@@ Lishu Duan, PhD – Abbvie ### 308995###Exhibitor Tutorial Presenter @@@ Rachel Forfar, PhD – MRC Technology ### 311653###Exhibitor Tutorial Presenter
12:30 PM - 1:45 PMLabcyte Exhibitor Tutorial: AstraZeneca, Labcyte, Brooks Life Science Systems and Titian Software: A collaboration to revolutionize sample management with acoustic tube-based storage and dispensing technologies. Pamela Lo ### 193058###Exhibitor Tutorial Organizer @@@ Clive Green – AstraZeneca ### 184212###Exhibitor Tutorial Presenter @@@ Brad Nelson – Labcyte ### 308678###Exhibitor Tutorial Presenter @@@ Robin Grimwood – Brooks Life Science Systems ### 308679###Exhibitor Tutorial Presenter @@@ Toby Winchester – Titian Software ### 308680###Exhibitor Tutorial Presenter
12:30 PM - 2:30 PMPerkinElmer Exhibitor Tutorial: Automated and Integrated Workflows for Genomic and Phenotypic Analysis in rapid drug discovery Pam Clemens ### 186764###Exhibitor Tutorial Organizer
1:00 PM - 1:30 PMSLAS Author Services Info Session: Meet SLAS Discovery Editor-in-Chief Robert Campbell of Eli Lilly and Company
1:00 PM - 2:00 PMCareer Connections
Mentoring 101 for Scientists Part II - Best Practices for the Mentor (And Anyone Can Be One!); Joanne Kamens, Ph.D. Executive Director, Addgene1:00 PM - 3:00 PMPoster Presentations (Even Numbered Posters)
1:30 PM - 2:00 PMSLAS Author Services Info Session: Distinguish Yourself in the Literature with ORCID
1:30 PM - 2:15 PMBeckman Coulter Exhibitor Tutorial: Accelerate Biomarker Discovery and Improve Results Using Automation Donna Gorman ### 184709###Exhibitor Tutorial Organizer @@@ Zach Smith, M.S. – Beckman Coulter Life Sciences ### 142428###Exhibitor Tutorial Presenter
2:00 PM - 2:30 PMSLAS Author Services Info Sessions: Social Media Strategies for Journal Authors Lynn Valastyan of SLAS and Beth Berry of SAGE Publishing
- 2:00 PM - 2:45 PMExhibitor TutorialExhibitor Tutorial
2:00 PM - 2:45 PMBiosero, Inc. Exhibitor Tutorial: Inaugural Green Button Go Automation and Scheduling Software User Group Meeting Kristen Macias ### 188232###Exhibitor Tutorial Organizer @@@ Prabhakar Henry – Biosero, Inc. ### 318115###Exhibitor Tutorial Presenter @@@ David Dambman – Biosero, Inc ### 119589###Exhibitor Tutorial Presenter
2:00 PM - 2:45 PMCellular Dynamics & Hamamatsu Exhibitor Tutorial: Calcium Handling Assays with Human iPSC-derived Cell Types Marissa Stafford ### 191357###Exhibitor Tutorial Organizer @@@ Coby B. Carlson, PhD – Cellular Dynamics International ### 44636###Exhibitor Tutorial Presenter
2:00 PM - 2:45 PMTTP Labtech Exhibitor Tutorial: Assay development into HTS: redefining reagent dispensing Joby Jenkins – TTP Labtech ### 43277###Exhibitor Tutorial Organizer @@@ Melanie Leveridge – GlaxoSmithKline, Stevenage UK ### 184211###Exhibitor Tutorial Presenter @@@ Joby Jenkins – TTP Labtech ### 43277###Exhibitor Tutorial Presenter
2:00 PM - 5:00 PMCareer Connections:
Mentoring Sessions / One-on-One Career Counseling Sessions / Job Boards in the SLAS Member Center2:30 PM - 3:00 PMBeverage Break in the Exhibition Hall
- 3:00 PM - 5:00 PMHard Targets - Success Through CollaborationsDrug Target Strategies
3:00 PM - 3:30 PMCase-study in consortium-based drug discovery: allosteric inhibition of the AAA ATPase p97 Michelle Arkin – University of California, San Francisco ### 61294###Speaker - Funded
3:30 PM - 4:00 PMDiscovery of Kynurenine Monooxygenase inhibitors for the prevention of multiple organ failure in Severe Acute Pancreatitis – an Industrial-Academic partnership Jon Hutchinson, BSc., PhD – GlaxoSmithKline ### 286969###Speaker - Not Funded
4:00 PM - 4:30 PMThe Dementia Consortium: building partnerships to address early stage neurodegeneration drug discovery Catherine A. Kettleborough – MRC Technology ### 193952###Speaker - Not Funded
4:30 PM - 5:00 PMCollaborative development of advanced bioluminescence resonance energy transfer approaches Kevin Pfleger, MA PhD – Harry Perkins Institute of Medical Research and The University of Western Australia ### 193538###Speaker - Not Funded
- 3:00 PM - 5:00 PMMaking Micro-Volume Biology Work: Tools, Techniques & SecretsMicro- and Nanotechnologies
3:00 PM - 3:30 PMOptically Actuated Micro-fluidics: Applications in BioMedical R&D Kevin T. Chapman – Berkeley Lights, Inc. ### 286947###Speaker - Not Funded
3:30 PM - 4:00 PM2017 SLAS Innovation Award Top 10 Finalist – Dynamic Profiling of Anti-tumor Immune Response at the Single-Cell Resolution by Microfluidic Cell Pairing Tania Konry – Northeastern University/HMS ### 286895###Speaker - Not Funded
4:00 PM - 4:30 PMMonoclonal Cell Line Generation and CRISPR/Cas9 Gene Knockout using Automated Single-Cell Electroporation Vincent Lemaitre ### 301014###Speaker - Not Funded
4:30 PM - 5:00 PMArrayed force-phenotyping of single-cells for high-throughput screening in drug discovery Ivan Pushkarsky – University of California, Los Angeles ### 184275###Speaker - Tony B. Awardee
- 3:00 PM - 5:00 PMMaking Scientific Data 100x Easier to UseData Analysis and Informatics
3:00 PM - 3:30 PMA comprehensive Information Management Strategy for the improvement of data and information quality across research Amy Kallmerten – Merck Research Labs ### 316214###Session Chair & Speaker - WITH Funding
3:30 PM - 4:00 PMManaging data-driven automation: Data workflows of an image-based automated cancer screen for cell viability and chemosensitivity Timothy Sherrill – Beckman Coulter ### 286940###Speaker - Not Funded
4:00 PM - 4:30 PMAnIML 1.0: Releasing a universal data format for analytical and biological data Burkhard Schaefer – BSSN Software GmbH ### 62433###Speaker - Not Funded
4:30 PM - 5:00 PMFrom patient to drug: Developing new drug strategies for patient profiles with text analytics and literature mining Brendon Kellner – PerkinElmer ### 119502###Speaker - Not Funded
- 3:00 PM - 5:00 PMRational Screen DesignAssay Development and Screening
3:00 PM - 3:30 PMPhenotypic personalized medicine as a powerful discovery platform for the optimization of multidrug treatments for cancer Patrycja Nowak-Sliwinska – University of Geneva ### 286924###Speaker - Tony B. Awardee
3:30 PM - 4:00 PMDesigning workflows and compound sets for combination screens Frederick J. King – The Genomics Institute of the Novartis Research Foundation ### 184291###Speaker - Not Funded
4:00 PM - 4:30 PMFragment-Based Assisted HTS: a Novel Approach to Traditional Drug Discovery Louis Scampavia – Scripps Florida; Department of Molecular Therapeutics ### 61255###Speaker - Funded
4:30 PM - 5:00 PMUsing Data to Decide Which Compounds to Screen: Considering Cytotoxicity in Compound Selection, and Utilizing ‘Informer Compound Sets’ and Iterative Screening to Decrease Experimental Effort and Cost Andreas Bender – University of Cambridge ### 61353###Speaker - Funded
- 3:00 PM - 5:00 PMUsing Physiologically-relevant Models for Automated ScreensAutomation and High-Throughput Technologies
3:00 PM - 3:30 PMReconciling Throughput and Physiological Relevance in High Throughput Screening Robert Damoiseaux, PhD – UCLA ### 185940###Speaker - Not Funded
3:30 PM - 4:00 PMHTS Tumor:Stroma Co-Culture Spheroid Platform Reveals CAF-Specific Chemotherapeutic Targets Shane Horman – GNF (Novartis) ### 72724###Session Chair & Speaker - WITH Funding
4:00 PM - 4:30 PMA novel high-throughput multi-parametric drug screening method for 3D tumor spheroids using Celigo image cytometer Steven Titus – NCATS/NIH ### 318742###Speaker - Not Funded
4:30 PM - 5:00 PMmicroHeart: A screening-ready, physiologically relevant human induced pluripotent stem cell-derived cardiomyocyte platform Fabian Zanella – StemoniX, Inc. ### 286942###Speaker - Not Funded
3:00 PM - 5:00 PMSpecial Session Panel Discussion: Whose Responsibility is Research Reproducibility? Cathy Tralau-Stewart – Catalyst & Associate Professor Therapeutics (AJ) , University of California San Francisco ### 185961###Session Chair & Speaker - WITH Funding @@@ Ivan Oransky – Retraction Watch ### 286884###Speaker - Funded @@@ Veronique Kiermer – PLOS ### 286885###Speaker - Not Funded @@@ Elizabeth Iorns, PhD – Science Exchange ### 119548###Speaker - Not Funded @@@ Tara A. Schwetz – National Institutes of Health ### 286966###Speaker - Not Funded @@@ Richard Neve – Gilead ### 318743###Speaker - Funded @@@ Richard Harris – NPR ### 318745###Moderator
3:00 PM - 6:00 PMPoster Dismantle
5:00 PM - 5:30 PMThe Lab Man Podcast -- How to Get More People to Read and Cite Your Research with Kudos and ORCID
5:00 PM - 6:00 PMReception in Exhibition Hall
6:30 PM - 9:30 PMTuesday Night Celebration – Newseum Sponsored by Hamilton
Sponsored By:6:30 AM - 7:30 AMSLAS FUNd Run 2017 ( NEW DATE! Wednesday)
Sponsored By:7:30 AM - 8:30 AMCANCELED: Surviving a Non-Academic Interview: What to Say, and When, Colin White, Ph.D., CEO and Founder, White Consulting
7:45 AM - 8:00 AMMorning Beverage Break
8:00 AM - 9:15 AMCareeer Connections:
SLAS Author Workshop: How to Prepare a Manuscript for Publication, SLAS Discovery Editor-in-Chief Robert M. Campbell, PhD (Eli Lilly & Co.) and SLAS Technology Editor-in-Chief Edward Kai-Hua Chow, PhD (National University of Singapore). Ed Chow ### 119608###Speaker @@@ Robert M. Campbell ### 319164###Speaker8:00 AM - 9:15 AMMarket Data & Trends in Life Sciences Research (Exhibitors Only) Mike Tice ### 308794###Speaker
- 8:00 AM - 9:15 AMSpecial Interest Group (SIG)Special Interest Group (SIG)
8:00 AM - 9:15 AMCompound Combination Special Interest Group (SIG) Oliver Leven – Genedata AG, Switzerland ### 184250###SIG Chair @@@ Rajarshi Guha – NCATS ### 61253###SIG Chair @@@ Eric Tang, PhD – Phoenix Biomedical Ltd. ### 316135###SIG Speaker - Funded @@@ Bill Markland ### 316136###SIG Speaker - Not Funded @@@ Lily Xiaoyan Shi ### 316172###SIG Speaker - Not Funded
8:00 AM - 9:15 AMLabware Leachables Special Interest Group (SIG) Lynn Rasmussen, MS – Southern Research Institute ### 43423###SIG Chair and Speaker - Funded @@@ David Weil, Ph.D – Agilent Technologies Inc. ### 316258###SIG Speaker - Not Funded
8:00 AM - 9:15 AMPhenotypic Drug Discovery Special Interest Group (SIG) Jonathan Lee – Eli Lilly ### 185951###SIG Chair @@@ Ellen L. Berg, PhD – DiscoverX ### 43332###SIG Speaker - Not Funded
8:00 AM - 9:15 AMuHTS Special Interest Group (SIG) Timothy Dawes ### 302258###SIG Chair @@@ Elliot E. Hui, PhD – University of California, Irvine ### 62454###SIG Speaker - Not Funded
8:00 AM - 9:15 AMWomen Professionals in Science and Technology Special Interest Group (SIG) Robyn Rourick – Genentech, Inc. ### 302257###SIG Chair @@@ Michelle Arkin – University of California, San Francisco ### 61294###SIG Chair
8:00 AM - 12:00 PMSpeaker Ready Room
8:00 AM - 1:30 PMRegistration Open
8:00 AM - 5:30 PMCoat & Luggage Check
9:00 AM - 9:30 AMMorning Beverage Break
9:00 AM - 1:00 PMExhibition Open
9:00 AM - 1:00 PMPoster Dismantle
9:15 AM - 9:30 AMNew Product Award Announcement
- 9:30 AM - 11:30 AMAutomating Novel Analytical Tools for PKA, Drug-Drug Combination and Synergy Assays, Drug RepurposingAutomation and High-Throughput Technologies
9:30 AM - 10:00 AMUnbiased high throughput drug combination screening identifies synergistic drug combinations effective in patient derived melanoma cell lines Paul A. Johnston – Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh ### 62456###Speaker - Not Funded
10:00 AM - 10:30 AMDrug repurposing identifies drug combinations to combat emerging infectious diseases Wei Sun – National Center for Advancing Translational Sciences ### 61267###Speaker - Not Funded
10:30 AM - 11:00 AMIdentification of KRAS Mutant Selective Inhibitors of Pancreatic Cancer Cell Growth Via Parallel Phenotypic High-throughput Screening of Approved Drugs Shurong Hou – The Scripps Research Institute Molecular Screening Center, The Scripps Research Institute - FL ### 286877###Speaker - Tony B. Awardee
11:00 AM - 11:30 AMRetrospective Analysis of 18 Activity Based Protein Profiling HTS Assays for the Identification of Selective Inhibitors of Disease Relevant Enzymes Virneliz Fernández Vega – Scripps Florida ### 286926###Speaker - Not Funded
- 9:30 AM - 11:30 AMBioprinting: Multidimensional Microscale Cellular/Tissue EngineeringMicro- and Nanotechnologies
9:30 AM - 10:00 AM3D Bioprinted tissue models for substance testing Markus Rimann – Zurich University of Applied Sciences ### 43424###Session Chair & Speaker - WITH Funding
10:00 AM - 10:30 AM2017 SLAS Innovation Award Top 10 Finalist – Rapid Multi-Material Extrusion Bioprinting Y. Shrike Zhang – Brigham and Women's Hospital, Harvard Medical School, Harvard-MIT Health Sciences and Technology ### 286964###Speaker - Not Funded
10:30 AM - 11:00 AMOvercoming chemoresistance from heterotypic cellular communication and physical stress in bioprinted and microfluidic 3D cancer models Imran Rizvi – Department of Dermatology, Massachusetts General Hospital, Harvard Medical School ### 184251###Speaker - Not Funded
11:00 AM - 11:30 AMPrecisely Engineered Cellular Arrayed Microenvironments for Highly Selective Cellular Activation and Screening Michael Floren, Ph.D. – University of Colorado Anschutz Medical Campus ### 286954###Speaker - Tony B. Awardee
- 9:30 AM - 11:30 AMInformatics of Drug Design and Compound Life Cycle ManagementData Analysis and Informatics
9:30 AM - 10:00 AMHarnessing and Sharing Science, Data and Knowledge Within an Organization Dmitry Lupyan – Schrodinger ### 283716###Session Chair & Speaker - No Funding
10:00 AM - 10:30 AMIn silico intervention to improve the quality of decisions in the Design-Make-Test cycle for small molecule drug discovery Farida Kopti – Merck & Co ### 283714###Speaker - Not Funded
10:30 AM - 11:00 AMThe Application of Project Management Tools and Practices to Lead Discovery in an Academic Environment Julianne Bryan, PMP – St. Jude Children's Research Hospital ### 286944###Speaker - Not Funded
11:00 AM - 11:30 AMMultiple Research Platforms: One Single Data Sharing Portal Farid Said – CSols, Inc. ### 286905###Speaker - Not Funded
- 9:30 AM - 11:30 AMRegenerative Medicine: Next Generation TreatmentsSpecial Session
9:30 AM - 10:00 AMProgress and Challenges in Translational iPS Cell Research Ilyas Singec – NIH/NCATS ### 286915###Speaker - Not Funded
10:00 AM - 10:30 AMAngiopellosis as an alternative mechanism of cell extravasation Ke Cheng – NC State University/UNC-Chapel Hill ### 286886###Speaker - Funded
10:30 AM - 11:00 AMModeling developmental brain disorders using patient-derived induced pluripotent stem cells Hongjun Song – Johns Hopkins University School of Medicine ### 286962###Speaker - Not Funded
11:00 AM - 11:30 AMStandardized generation of patient-specific and gene-corrected induced pluripotent stem cell lines for disease modeling and drug screening Lise Munsie – CCRM ### 286908###Speaker - Funded
- 9:30 AM - 11:30 AMScreening the UndruggableAssay Development and Screening
9:30 AM - 10:00 AMInterrogating Protein-Protein Interactions in Cancer Haian Fu – Emory Chemical Biology Discovery Center, Emory University School of Medicine ### 286945###Speaker - Funded
10:00 AM - 10:30 AMHot spotting with thermal scanning: a ligand- and structure-independent assessment of target drugability/ligandability Stefan Geschwindner – Discovery Sciences, AstraZeneca R&D Gothenburg ### 185943###Speaker - Funded
10:30 AM - 11:00 AMIdentifying Allosteric Modifiers of K-Ras using Second Harmonic Generation Frank McCormick – University California San Francisco ### 286932###Speaker - Not Funded
11:00 AM - 11:30 AMDrugging Protein Phosphatases for the Treatment of Cancers John S. Lazo, PhD – University of Virginia ### 283715###Session Chair & Speaker - WITH Funding
- 9:30 AM - 11:30 AMUniting Phenotypic and Target-Based Drug DiscoveryDrug Target Strategies
9:30 AM - 10:00 AMDifferences in the Therapeutic Hypotheses associated with Phenotypic and Target-Based screening. David C. Swinney, PhD – Institute for Rare and Neglected Diseases Drug Discovery ### 61363###Speaker - Funded
10:00 AM - 10:30 AMCombining of Phenotypic and Target-based Approaches Helped Identification and Characterization of Antiviral Activity of GS-5734. Veronica Soloveva, Ph.D – USAMRIID/HJF ### 286918###Speaker - Funded
10:30 AM - 11:00 AMCombining Target-Based and Phenotypic Discovery Assays for Drug Repurposing Sharlene Velichko – DiscoverX, BioSeek Division ### 286948###Speaker - Not Funded
11:00 AM - 11:30 AMPhenotypic screening identifies a small molecule that inhibits PCSK9 protein translation and directly binds to the human 80S ribosome Paula M. Loria – Pfizer ### 286961###Speaker - Not Funded
10:00 AM - 11:00 AMThe Lab Man Podcast - The Lab Man Interviews New Product Award winners
11:30 AM - 12:00 PMLunch in the Exhibition Hall
11:45 AM - 12:00 PMPassport to Prizes Award Announcements
12:00 PM - 12:45 PMHamilton Exhibitor Tutorial: Using high-throughput automation to democratize access to genetic information Claire Rhodes ### 306943###Exhibitor Tutorial Organizer @@@ Justin Lock – Color Genomics ### 298525###Exhibitor Tutorial Presenter
- 12:00 PM - 1:15 PMSpecial Interest Group (SIG)Special Interest Group (SIG)
12:00 PM - 1:15 PMAcademic Drug Discovery Special Interest Group (SIG) Andrew D. Napper, PhD ### 119506###SIG Chair and Speaker - Funded @@@ James Inglese, PhD – NIH/NCATS ### 62455###SIG Speaker - Not Funded @@@ J. Todd Abrams, Ph.D – Temple University ### 316247###SIG Speaker - Not Funded @@@ Marlene Jacobson – Moulder Center for Drug Discover Research, Temple University School Of Pharmacy ### 72879###SIG Chair
12:00 PM - 1:15 PMADMET Special Interest Group (SIG) Ritu Singh ### 302259###SIG Chair @@@ Amy Siu, MS – Eisai Inc. ### 302260###SIG Speaker - Funded
12:00 PM - 1:15 PMAutomation Quality Control Special Interest Group (SIG) John T. Bradshaw, PhD – Artel ### 184708###SIG Chair and Speaker - Funded
12:00 PM - 1:15 PMStandards Initiatives Special Interest Group (SIG) Burkhard Schaefer – BSSN Software GmbH ### 62433###SIG Chair @@@ Dana Vanderwall – Bristol-Myers Squibb ### 62466###SIG Chair
- 1:30 PM - 3:30 PMCellular Manipulation and Genome Editing in Screening Assay DesignAssay Development and Screening
1:30 PM - 2:00 PMDeveloping CRISPR/Cas9 tools to functionalize the coding and noncoding genome. Joana A. Vidigal – Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center ### 286968###Speaker - Funded
2:00 PM - 2:30 PMDroplet microfluidic- based 3D tumor models for cancer therapeutic screening Pooja Sabhachandani – Northeastern University ### 286914###Speaker - Not Funded
2:30 PM - 3:00 PMGenome-wide siRNA high-content screen identifies novel muscle differentiation regulators as therapeutic targets for rhabdomyosarcoma Yueming Wang, PhD – High-Throughput Bioscience Center, Chemical Biology and Therapeutics, St. Jude Children's Research Hospital ### 184260###Speaker - Not Funded
3:00 PM - 3:30 PMA Genome-wide pooled CRISPR knockout screen identifies necrosome regulatory mechanisms. Marinella G. Callow, BSc – Genentech inc. ### 286963###Speaker - Not Funded
- 1:30 PM - 3:30 PMIn-house Automation: Devices and Software Developed InternallyAutomation and High-Throughput Technologies
1:30 PM - 2:00 PMGlobal Innovations and Technologies Team (GLINT): Building (in-house) Advancements for Science and Technology Matthew Boeckeler – AstraZeneca PLC ### 286890###Speaker - Not Funded
2:00 PM - 2:30 PMAutomated Magnetic Bead Protein Purification Justin Provchy – Amgen ### 286967###Speaker - Not Funded
2:30 PM - 3:00 PMLab-Made Technology for NGS Library Construction at the BC Cancer Agency Robin JN. Coope, PhD, PEng – BC Cancer Agency Genome Sciences Centre ### 286946###Speaker - Not Funded
3:00 PM - 3:30 PMThe PetriJet laboratory automation platform- one device to rule them all Christoph Otto – University of Technology Dresden ### 199112###Speaker - Not Funded
- 1:30 PM - 3:30 PMMicrophysiological SystemsMicro- and Nanotechnologies
1:30 PM - 2:00 PMOrgans-on-Chips: Micro-engineered environments for studying human tissues functions Ville Kujala ### 333531###Presenter
2:00 PM - 2:30 PMA Microfluidic Model of Kidney and Other Transport Tissues for 96-Well Format Screening of Therapeutics Joseph L. Charest – Draper ### 286960###Speaker - Not Funded
2:30 PM - 3:00 PMMechanically actuatable airway disease-on-a-chip: a novel platform to study biomechanical basis of human lung disease Jungwook Paek – Department of Bioengineering, University of Pennsylvania ### 286956###Speaker - Not Funded
3:00 PM - 3:30 PMPerfused intestinal Caco-2 tubules suitable for high throughput screening Remko van Vught – MIMETAS B.V. ### 184228###Speaker - Not Funded
- 1:30 PM - 3:30 PMNon-Traditional Modalities as TherapeuticsDrug Target Strategies
1:30 PM - 2:00 PMDesign Considerations for Synthetic Macrocycles as Drugs Adrian Whitty, PhD – Boston University ### 286880###Speaker - Funded
2:00 PM - 2:30 PMDevelopment of an ELT Selection Method for Irreversible Inhibitors Zhengrong Zhu – GlaxoSmithKline ### 286882###Speaker - Not Funded
2:30 PM - 3:00 PMSmall Libraries, Big Impact: Leveraging focused screens for rapid identification of target space/vulnerabilities. Robert L. Hills – Wistar Institute ### 286935###Speaker - Not Funded
3:00 PM - 3:30 PMMessenger RNA as a novel therapeutic platform Tej Pavoor – Moderna Therapeutics ### 286901###Speaker - Not Funded
- 1:30 PM - 3:30 PMThe Digital Dark Hole: Handling Large-Scale Data for Use, Reuse, and SharingData Analysis and Informatics
1:30 PM - 2:00 PMA Reproducible Science Platform for Translational Bioinformatics Andrew Smith – Bristol-Myers Squibb ### 316084###Speaker - Not Funded
2:00 PM - 2:30 PMPubChem BioAssay: a continuous effort towards open HTS data sharing Yanli Wang – National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health ### 184204###Speaker - Not Funded
2:30 PM - 3:00 PMThe Visual Assay™ Platform: Using Mobile Devices and Workflow Technology In the Lab to Capture & Share Assay Data For Improved Data Integrity and Reproducibility Mannix Aklian – Label Independent, Inc ### 184226###Speaker - Not Funded
3:00 PM - 3:30 PMPublishing Data: Credit Where Credit is Due Laurie Goodman – GigaScience ### 283709###Session Chair & Speaker - No Funding
3:30 PM - 3:45 PMBeverage Break
3:45 PM - 5:00 PMKeynote Session and Innovation Award Announcement: Rachel Swaby, Author of Headstrong: 52 Women Who Changed Science—and the World Rachel Swaby ### 309322###Keynote Speaker
- 5:00 PM - 5:30 PMRachel Swaby Book Signing