Presentations on
Monday, February 6, 2017
7:30 AM - 6:00 PMRegistration Open
8:00 AM - 8:30 AMMorning Beverage Break
8:00 AM - 5:00 PMSpeaker Ready Room
8:00 AM - 6:15 PMCoat & Luggage Check
8:30 AM - 9:00 AMKeynote Session: Welcome and Opening Remarks
9:00 AM - 10:00 AMKeynote: Jennifer Lippincott-Schwartz; Group Leader, Howard Hughes Medical Institute’s Janelia Research Jennifer Lippincott-Schwartz – Howard Hughes Medical Institute's Janelia Research Campus ### 309320###Keynote Speaker
10:00 AM - 10:30 AMBeverage Break in the Exhibition Hall
10:00 AM - 12:00 PMPoster Setup
10:00 AM - 1:00 PMCareer Connections:
Mentoring Sessions / One-on-One Career Counseling Sessions / Job Boards in the SLAS Member Center10:00 AM - 6:00 PMExhibition Open
10:00 AM - 6:00 PMPoster Viewing in Exhibition Hall
- 10:30 AM - 12:30 PMAdvances in Genome Editing TechnologiesCellular Technologies
10:30 AM - 11:00 AMComparison of Cas9 activators in multiple species. Alejandro Chavez, MD/PhD – Wyss Institute at Harvard ### 286878###Speaker - Tony B. Awardee
11:00 AM - 11:30 AMGenome engineering with targeted recombinases Thomas Gaj – University of California, Berkeley ### 286917###Speaker - Funded
11:30 AM - 12:00 PMUsing engineered model organisms and high throughput screening tools to automate and scale the drug discovery process for rare genetic diseases Tom Hartl, PhD – Perlara, PBC ### 298514###Speaker - Not Funded
12:00 PM - 12:30 PMGenome ad Epigenome Editing with ZFNS and CRISPR Gregory Davis – MIlliporeSigma ### 283706###Session Chair & Speaker - No Funding
- 10:30 AM - 12:30 PMDigital and Droplet MicrofluidicsMicro- and Nanotechnologies
10:30 AM - 11:00 AMDrop Based Microfluidics and the Quantitative Biology Revolution Assaf Rotem – Harvard University ### 286955###Speaker - Funded
11:00 AM - 11:30 AMDroplet based functional assay for detecting protease secretion from circulating tumor cells Manjima Dhar – UCLA ### 286898###Speaker - Tony B. Awardee
11:30 AM - 12:00 PMRapid access to libraries of non-rule-of-five chemotypes via DNA-encoded solid-phase combinatorial synthesis Marie L. Malone – The Scripps Research Institute ### 286943###Speaker - Tony B. Awardee
12:00 PM - 12:30 PMStability of water-in-oil droplets as micro-reactors for ultrahigh-throughput droplet microfluidics applications Sindy KY. Tang – Stanford University ### 184225###Speaker - Funded
- 10:30 AM - 12:30 PMLabel Free Bioanalytical Techniques for Hit Identification and OptimisationAdvances in Bioanalytics, Biomarkers and Diagnostics
10:30 AM - 11:00 AMHigh-throughput MALDI TOF mass spectrometry for drug discovery in the ubiquitin system
Matthias Trost – MRC PPU, University of Dundee ### 286921###Speaker - FundedSponsored By:
11:00 AM - 11:30 AMHigh throughput acoustic mass spectrometry: Development and delivery of a biochemical screen
Jonathan Wingfield – AstraZeneca, Discovery Sciences ### 119486###Speaker - Not FundedSponsored By:11:30 AM - 12:00 PMThe Use of Backscattering Interferometry to Study Compound Binding to GPCRs
Jonathan M. Ellery – Takeda Cambridge Ltd ### 286887###Speaker - FundedSponsored By:12:00 PM - 12:30 PMHigh Throughput Screening and Label-Free Characterization of Molecular Interactions Using a 32-spot Array
Klaus Wiehler – Sierra Sensors GmbH ### 286933###Speaker - Not FundedSponsored By:
- 10:30 AM - 12:30 PMLet There Be Light: Informatics Approaches to Exploring the Dark GenomeData Analysis and Informatics
10:30 AM - 11:00 AMIlluminating the Druggable Proteome Tudor I. Oprea, MD, PhD – UNM School of Medicine ### 286930###Speaker - Not Funded
11:00 AM - 11:30 AMOpen Targets Platform: mining gene-disease evidence for improved drug target selection Denise Carvalho-Silva – Open Targets - EMBL-EBI ### 286891###Speaker - Funded
11:30 AM - 12:00 PMDr. Gene Budger: A Web Application to Predict Drugs to Modulate the Expression of a Specific Gene Avi Maayan ### 289625###Speaker - Not Funded
12:00 PM - 12:30 PMGene-network based predictive modeling to identify biomarkers for high dimensional genomic data Viswanath Devanarayan, PhD – AbbVie ### 286929###Speaker - Funded
- 10:30 AM - 12:30 PMPhenotypic and High Content Screening AssaysAssay Development and Screening
10:30 AM - 11:00 AMKinetic Imaging of Calcium and Voltage Activity in hiPSC-Derived Dopaminergic Neurons Relevant to Parkinson’s Jeffrey Price, PhD – Vala Sciences ### 298517###Presenter
11:00 AM - 11:30 AMHigh-content imaging and single cell analysis for the systematic discovery and molecular dissection of novel pathways regulating nuclear architecture Gianluca Pegoraro – High-Throughput Imaging Facility/Center for Cancer Research/NCI/NIH ### 286893###Speaker - Not Funded
11:30 AM - 12:00 PMParsing cellular homogeneity from heterogeneous stem cell cultures Daniel Hoeppner – Lieber Institute ### 286957###Speaker - Not Funded
12:00 PM - 12:30 PMLight sheet microscopy for high content 3-D imaging of 3-D tissue cultures in a 96-well plate format Vincent Maioli – Imperial College London ### 318744###Speaker - Not Funded
- 10:30 AM - 12:30 PMScreening Automation: Modular vs. Highly integrated systemsAutomation and High-Throughput Technologies
10:30 AM - 11:00 AMDevelopment of Small Modular Systems to Enable New Scientific Applications Jason Matzen – The Genomics Institute of the Novartis Research Foundation ### 185954###Speaker - Not Funded
11:00 AM - 11:30 AMConnecting Hits to Leads through Fit-for-Purpose Automation Solutions Jonathan S. Lippy – Bristol Myers Squibb ### 286927###Speaker - Not Funded
11:30 AM - 12:00 PMModular, fully integrated or collaborative automation – what happens when you want it all ? Mark Wigglesworth – AstraZeneca - Discovery Sciences ### 119521###Speaker - Not Funded
12:00 PM - 12:30 PMIterative Design of an Automated Organism Foundry Jeff Z. Lou – Ginkgo Bioworks ### 286937###Speaker - Not Funded
- 12:30 PM - 1:15 PMExhibitor TutorialExhibitor Tutorial
12:30 PM - 1:15 PMBMG LABTECH Exhibitor Tutorial: How to Perform Real-Time, Walk-Away, Cell Health Assays Carl Peters – BMG LABTECH ### 45027###Exhibitor Tutorial Organizer @@@ Andrew Niles – Promega ### 308630###Exhibitor Tutorial Presenter @@@ Carl Peters – BMG LABTECH ### 45027###Exhibitor Tutorial Presenter
12:30 PM - 1:15 PMTitian Software Exhibitor Tutorial: Bristol-Myers Squibb, Titian Software, HighRes Biosolutions: A collaboration to implement seamless workflow management. Angela Cunniff ### 188225###Exhibitor Tutorial Organizer @@@ Jefferson Chin – Bristol-Myers Squibb ### 125019###Exhibitor Tutorial Presenter @@@ Anne Vergnon – Titian Software ### 125037###Exhibitor Tutorial Presenter @@@ Ira Hoffman – HighRes Biosolutions ### 309017###Exhibitor Tutorial Presenter
12:30 PM - 1:30 PMLunch in the Exhibition Hall Sponsored Drug Target Review
Sponsored By:
- 12:30 PM - 1:45 PMExhibitor TutorialExhibitor Tutorial
12:30 PM - 1:45 PMBiosero Tutorial: Applications of Green Button Go Automation Scheduling Software for Small and Large Automation Platforms Kristen Macias ### 188232###Exhibitor Tutorial Organizer @@@ John Cesarek – Zymergen, Inc. ### 317167###Exhibitor Tutorial Presenter @@@ Harry Woodcock – Vertex Pharmaceuticals ### 318117###Exhibitor Tutorial Presenter
12:30 PM - 1:45 PMLabcyte Exhibitor Tutorial: Genomic Applications using the Labcyte Echo® Series of Liquid Handlers Pamela Lo ### 193058###Exhibitor Tutorial Organizer @@@ John Lesnick – Labcyte Inc ### 125074###Exhibitor Tutorial Presenter
12:30 PM - 1:45 PMMolecular Devices Exhibitor Tutorial: High-throughput analysis of complex 3D cell models, including iPSC-derived liver cells through new, automated techniques Caryn Tyler ### 188245###Exhibitor Tutorial Organizer @@@ Cathy Olsen, Ph.D – Molecular Devices ### 43417###Exhibitor Tutorial Presenter @@@ Grischa Chandy, Ph.D – Molecular Devices ### 196827###Exhibitor Tutorial Presenter @@@ Jayne Hesley – Molecular Devices LLC ### 72870###Exhibitor Tutorial Presenter @@@ Steve Wiltgen, Ph.D – Molecular Devices ### 318529###Exhibitor Tutorial Presenter
12:30 PM - 1:45 PMThermo Fisher Scientific Exhibitor Tutorial: Synthetic Biology Automation Christa Lamps ### 188845###Exhibitor Tutorial Organizer @@@ Huimin Zhao, Ph.D – University of Illinois, Urbana-Champaign (UIUC) ### 194011###Exhibitor Tutorial Presenter @@@ Ying-Jing Yuan ### 318188###Exhibitor Tutorial Presenter @@@ Hille Tekotte – University of Edinburgh ### 318189###Exhibitor Tutorial Presenter @@@ Axel Trefzer ### 318190###Exhibitor Tutorial Presenter
12:30 PM - 2:30 PMPerkinElmer Exhibitor Tutorial: An End-To-End 3D Cell Culture Workflow: Grow, Read, Decide Pam Clemens ### 186764###Exhibitor Tutorial Organizer
1:00 PM - 1:30 PMSLAS Author Services Info Session: Meet SLAS Technology Editor-in-Chief Edward Kai-Hua Chow of the National University of Singapore
1:00 PM - 2:00 PMCareer Connections
Mentoring 101 for Scientists Part I - Finding Mentors and Being the Best Mentee You Can Be; Joanne Kamens, Ph.D., Executive Director, Addgene1:00 PM - 3:00 PMPoster Presentations (Odd Numbered Posters)
1:30 PM - 2:00 PMSLAS Author Services Info Sessions: Using Kudos to Get More People to Read and Cite Your Research Beth Berry of SAGE Publishing
2:00 PM - 2:30 PMSLAS Author Services Info Sessions: Accelerate Life Sciences Research with Atypon Literatum Beth Berry of SAGE Publishing
- 2:00 PM - 2:45 PMExhibitor TutorialExhibitor Tutorial
2:00 PM - 2:45 PMGenedata Screener for SPR: An Efficient Solution for Small and Large Molecule Screening Analysis Workflows Michaela Kraus ### 289622###Exhibitor Tutorial Organizer @@@ Spencer Carson – Genedata Inc. ### 308968###Exhibitor Tutorial Presenter
2:00 PM - 2:45 PMIntelliCyt Exhibitor Tutorial: Phenotypic Screening Realized. Breaking new ground in suspension cell screening with the IntelliCyt platform Joe Zock – IntelliCyt Corporation ### 297577###Exhibitor Tutorial Organizer @@@ Dave Gephard, MS – Pfizer ### 311369###Exhibitor Tutorial Presenter @@@ Catherine Bardelle, PhD – AztraZeneca UK ### 311370###Exhibitor Tutorial Presenter
2:00 PM - 2:45 PMLab Services B.V. Exhibitor Tutorial: Automated Platform & Method Design; Optimized by Simulation Ir. Ferry de Vugt – Lab Services ### 316792###Exhibitor Tutorial Organizer @@@ Ir. Ferry de Vugt – Lab Services bv ### 319094###Exhibitor Tutorial Presenter
2:00 PM - 2:45 PMLumigen Exhibitor Tutorial: A High Throughput Immunoassay Application: Monoclonal Antibody Screening Kristen Pauly ### 190682###Exhibitor Tutorial Organizer
2:00 PM - 2:45 PMMultispan Exhibitor Tutorial: Striking a balance between physiologically relevant GPCR Assays and suitability for screening Alex Batchelor – Multispan, Inc. ### 43293###Exhibitor Tutorial Organizer @@@ Lisa Minor, Ph.D – Multispan, Inc. ### 187995###Exhibitor Tutorial Presenter
2:00 PM - 2:45 PMParker Hannifin Exhibitor Tutorial: How automated cell analysis and selection creates standardization in the differentiation and expansion process Brian Handerhan – Parker Hannifin ### 302803###Exhibitor Tutorial Organizer @@@ George F. Muschler, MD – Cleveland Clinic, Lerner Research Institute ### 318229###Exhibitor Tutorial Presenter
2:00 PM - 2:45 PMTakara Bio, Inc. Exhibitor Tutorial: Efficient, footprint-free gene editing of iPS cells using CRISPR/Cas9 for disease modeling and drug screening applications Liz Quinn, PhD – Takara Bio USA, Inc. ### 317278###Exhibitor Tutorial Organizer
2:00 PM - 2:45 PMThermo Fisher Scientific Exhibitor Tutorial: New fully automated system for nucleic acid and protein purification Christa Lamps ### 188845###Exhibitor Tutorial Organizer @@@ Xingwang Fang, PhD – ThermoFisher Scientific ### 318191###Exhibitor Tutorial Presenter
2:00 PM - 5:00 PMCareer Connections:
Mentoring Sessions / One-on-One Career Counseling Sessions / Job Boards in the SLAS Member Center2:30 PM - 3:00 PMBeverage Break in the Exhibition Hall
- 3:00 PM - 5:00 PMBiochemical and Biophysical ScreeningAssay Development and Screening
3:00 PM - 3:30 PMUse of Biophysical Technologies to Identify and Characterize Hit Compounds for NR3A Subunit of NMDA Receptors Chen-Ting Ma – Sanford Burnham Prebys Medical Discovery Institute ### 286950###Speaker - Funded
3:30 PM - 4:00 PMAnalysis of bispecific interactions with the switchSENSE biosensor Ulrich Rant – Dynamic Biosensors GmbH ### 72743###Speaker - Not Funded
4:00 PM - 4:30 PMTargeting Structurally and Functionally Diverse Nucleic Acids with Druglike Small Molecules John S. Schneekloth, Jr. – Chemical Biology Laboratory, National Cancer Institute ### 286904###Speaker - Not Funded
4:30 PM - 5:00 PMUnlocking the RNA target space: In search for selective small molecule RNA binders Razvan Nutiu – NIBR ### 283717###Session Chair & Speaker - No Funding
- 3:00 PM - 5:00 PMDevelopment of Cellular Models for Phenotypic ScreeningCellular Technologies
3:00 PM - 3:30 PMSystematic validation of disease-specific genetic association data in cellular models Joel A. Klappenbach – Merck & Co., Inc. ### 286899###Session Chair & Speaker - No Funding
3:30 PM - 4:00 PMCalibrating human adipocyte assays for type 2 diabetes target validation Amit Majithia – Broad Institute/ Massachusetts general hospital ### 286934###Speaker - Funded
4:00 PM - 4:30 PMDeveloping assay technologies to realize the potential of iPSC technology in drug discovery Han Xu – Amgen Inc ### 286931###Speaker - Not Funded
4:30 PM - 5:00 PMToward primary drug screening using iPSC-derived human motor neurons in 1536-well plates Zhong-Wei Du, PhD – BrainXell, Inc. ### 286941###Speaker - Not Funded
- 3:00 PM - 5:00 PMHigh Content and High Throughput AutomationAutomation and High-Throughput Technologies
3:00 PM - 3:30 PMPast, present & future – AstraZeneca’s experience, learning and vision in the delivery of automated High Content Screening Paul Harper – AstraZeneca ### 286936###Speaker - Not Funded
3:30 PM - 4:00 PMMultiplexed Live Cell Phenotypic Screening: Cell level vs Multi-variant Well Level Analysis James LaRocque – AMRI ### 286907###Speaker - Not Funded
4:00 PM - 4:30 PMThe European Lead Factory: an efficient open-innovation platform with unique screening capabilities Steven van Helden – Pivot Park Screening Centre ### 78012###Speaker - Not Funded
4:30 PM - 5:00 PMApp Store and High Performance Computing for High Content Screening Seungtaek Lee – PerkinElmer ### 286953###Speaker - Not Funded
- 3:00 PM - 5:00 PMPerspectives on Commercialization of Integrated Micro and Nanofluidic DevicesMicro- and Nanotechnologies
3:00 PM - 3:30 PM2017 SLAS Innovation Award Top 10 Finalist – Optimizing Clinical Combination Therapy Using a Phenotypic Personalized Medicine Technology Platform Dean Ho, Ph.D. – UCLA Bioengineering and The Weintraub Center ### 286896###Speaker - Not Funded
3:30 PM - 4:00 PM2017 SLAS Innovation Award Top 10 Finalist – Transcriptional profiling of single cells using droplet microfluidics Tobias Wheeler – 10X Genomics ### 286894###Speaker - Not Funded
4:00 PM - 4:30 PMMicrofluidics without Borders: Commercialization Perspectives of High Throughput Applications for Acoustic Droplet Ejection Technology Sammy Datwani – Labcyte Inc. ### 43354###Session Chair & Speaker - WITH Funding
4:30 PM - 5:00 PM2017 SLAS Innovation Award Top 10 Finalist – Vortex Biosciences technology for fast and label-free isolation of circulating tumor cells from blood samples Elodie Sollier-Christen – Vortex Biosciences, Inc. ### 286889###Speaker - Funded
- 3:00 PM - 5:00 PMTargeted Biomarker AnalysisAdvances in Bioanalytics, Biomarkers and Diagnostics
3:00 PM - 3:30 PMEffect of Controlled Diet on Biomarker Measurements in the Clinic
Petia Shipkova – Bristol-Myers Squibb ### 286959###Speaker - Not FundedSponsored By:3:30 PM - 4:00 PMThe SOMAscan® assay and SOMAmer® reagents: Translatable tools from high-throughput biomarker discovery to targeted assays
Sheri K. Wilcox – SomaLogic, Inc. ### 286911###Speaker - Not FundedSponsored By:4:00 PM - 4:30 PM2017 SLAS Innovation Award Top 10 Finalist – Inkjet printing technology for facilitated at will antimicrobial susceptibility testing (FAST) in under 5 hours: addressing the needs of a so-called 'post-antibiotic era'.
James E. Kirby, MD – Beth Israel Deaconess Medical Center and Harvard Medical School ### 286912###Speaker - Not FundedSponsored By:4:30 PM - 5:00 PMEarwax: A Neglected Body Secretion or a Step Ahead in Clinical Diagnosis!
Engy Shokry. Shokry, Masters and PhD of Pharmaceutical Sciences, Postdoctoral fellow in Meyer Children Hospital (Italy) – Laboratory of Methods of Extraction and Separation, Institute of Chemistry, Federal University of Goias (LAMES-IQ-UFG) (Laboratório de Métodos de Extração e Separação, Instituto de Química, Universidade Federal de Goiás ) ### 286916###Speaker - Tony B. AwardeeSponsored By:
- 3:00 PM - 5:00 PMThe Challenges and Benefits of CollaborationData Analysis and Informatics
3:00 PM - 3:30 PMHow Can Informatics Systems Help External Collaborations Succeed?
Robert D. Brown – Dotmatics Inc ### 286888###Speaker - Not FundedSponsored By:
3:30 PM - 4:00 PM'Virtual' R&D in Pharma: What are the Virtues (and Vices)?
Steven Wesolowski – Xenon Pharmaceuticals ### 286965###Speaker - FundedSponsored By4:00 PM - 4:30 PMHow to solve the logistical challenges of collaborating to enable efficient access to innovation and expertise.
Elizabeth Iorns, PhD – Science Exchange ### 119548###Speaker - Not FundedSponsored By4:30 PM - 5:00 PMUtilizing Cloud Technology to Solve Challenges in Modern Laboratories
Marc A. Daxer – Fraunhofer Institute for Manufacturing Engineering and Automation IPA ### 286923###Speaker - Tony B. AwardeeSponsored By
5:00 PM - 5:15 PMStudent Poster Award Winner Announcement
5:00 PM - 6:00 PMReception in Exhibition Hall Celebrating the 2016 SLAS Journal Achievement Award Honorees
5:00 PM - 6:00 PMStudent and Early Career Professionals Mixer
5:00 PM - 6:00 PMThe Lab Man Podcast - The Lab Man Interviews the Student Poster Winners
- 6:00 PM - 8:00 PMLate Night with LRIG - Rapid-Fire Innovation SessionLate Night with LRIG
6:00 PM - 6:40 PMinfinitesimal's New Single Cell Transfection System Jonathon J. Prinz – infinitesimal LLC ### 323055###Exhibitor Tutorial Speaker
6:00 PM - 6:40 PMLabel-Free Ultra-High Throughput Screening by MALDI Mass Spectrometry: One Million Samples per Week Jens Fuchser – Bruker Daltonics ### 315725###Exhibitor Tutorial Speaker
6:00 PM - 6:40 PMLionheart FX Automated Live Cell Imager Caleb Foster – BioTek Instruments, Inc. ### 316927###Exhibitor Tutorial Speaker
6:00 PM - 6:40 PMMicro Dispense – New Precision in Liquid Handling Thomas P. Weisener, Dr. – HNP Mikrosysteme GmbH ### 314733###Exhibitor Tutorial Speaker
6:00 PM - 6:40 PMNanotech Biomachines, Inc. (Nanotech Bio): The Rise of Bioelectronic Lead Discovery Will Martinez – Nanotech Biomachines, Inc. ### 316243###Exhibitor Tutorial Speaker
6:00 PM - 6:40 PMNot All Cell Lines Are Created Equal - Impact of Surface Expression on GPCR Assays Alex Batchelor – Multispan, Inc. ### 43293###Exhibitor Tutorial Speaker
6:40 PM - 7:20 PMAcouTrap: Trapping and enriching cells, bacteria and extracellular vesicles using ultrasound Torsten Freltoft, MSc, PhD – AcouSort AB ### 315726###Exhibitor Tutorial Speaker
6:40 PM - 7:20 PMAssay Development into HTS: Redefining Reagent Dispensing Joby Jenkins – TTP Labtech ### 43277###Exhibitor Tutorial Speaker
6:40 PM - 7:20 PMCreoptix WAVE - Kinetics at High Sensitivity and with Crude Samples Matyas Vegh – Creoptix ### 315724###Exhibitor Tutorial Speaker
6:40 PM - 7:20 PMQuantitative Immunoassays in 10 minutes Claudio Rhyner – Davos Diagnostics AG ### 315727###Exhibitor Tutorial Speaker
6:40 PM - 7:20 PMIntroducing the latest advance for iQue Screener PLUS: Fast is now even more “EXCITING”! Joseph Zock – IntelliCyt Corporation ### 316926###Exhibitor Tutorial Speaker
6:40 PM - 7:20 PMBioDep - An Entirely New Bio-Coating Technology Liam O'Neill, PhD – Theradep Technologies ### 316245###Exhibitor Tutorial Speaker
7:25 PM - 8:00 PMA New Device for Rapid Ultrasensitive Drug Binding Measurements Brett Goldsmith – Nanomedical Diagnostics ### 315723###Exhibitor Tutorial Speaker
7:25 PM - 8:00 PMDirect Mark ID Technology Jeff Denton – Computype ### 314734###Exhibitor Tutorial Speaker
7:25 PM - 8:00 PMIntroduction to MIP Diagnostics Ltd. - "Plastic antibodies" Francesco Canfarotta – MIP Diagnostics Limited ### 316242###Exhibitor Tutorial Speaker
7:25 PM - 8:00 PMRevolutionary Compound Distribution Workstation - Flex Swile Ed Halpin – Chemspeed Technologies Inc. ### 298543###Exhibitor Tutorial Speaker
7:25 PM - 8:00 PMUpcyte - Expanded Primary Cells Astrid Nörenberg, PhD – upcyte technologies GmbH ### 188032###Exhibitor Tutorial Speaker
- 6:30 PM - 8:30 PMSLAS Student and Early Career Professionals Event at Lucky Strike
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