Autoimmune neurologic diseases

Oral

Dysregulation of B Cells in Myalgic Encephalomyelitis/chronic Fatigue Syndrome

Thursday, June 15
5:45 PM - 7:00 PM

[Objective] Myalgic encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a severely debilitating disease of unknown etiology. The core symptoms of ME/CFS are profound fatigue, post-exertional malaise, cognitive impairment, sleep abnormalities and orthostatic intolerance. Various immune impairments have been described and remarkably, about two thirds of ME/CFS patients receiving B cell depletion therapy by rituximab had a clinical response. However, the underlying mechanism of the therapeutic effect of rituximab on ME/CFS patients is still unclear. The aim of this study is to evaluate immune abnormalities in ME/CFS patients.

Hirohiko Ono

Department of Immunology, National Institute of Neuroscience, NCNP, Japan

Presentation(s):

    Send Email for Hirohiko Ono

    Wakiro Sato

    Department of Immunology, National Institute of Neuroscience, NCNP, Japan

    Presentation(s):

      Send Email for Wakiro Sato

      Takashi Yamamura

      Department of Immunology, National Institute of Neuroscience, NCNP, Japan

      Presentation(s):

        Send Email for Takashi Yamamura


        Assets

        Dysregulation of B Cells in Myalgic Encephalomyelitis/chronic Fatigue Syndrome



        Attendees who have favorited this

        Send Email for Dysregulation of B Cells in Myalgic Encephalomyelitis/chronic Fatigue Syndrome