Thematic

Microbiome/Immune Interactions

Thursday, June 15
1:00 PM - 2:45 PM

Alexander Chervonsky

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Laurence Zitvogel

Prof
Institut Gustave Roussy

Pr L. Zitvogel, MD (clinical oncology), PhD (tumor immunology), PU-PH Faculty Paris Sud, University Paris XI (Clinical Biology), graduated in Medical Oncology from the School of Medicine of the University of Paris in 1992. She started her scientific career when she was at the University of Pittsburgh in the USA in Michael Lotze’s laboratory. She became Research Director at Institut National de la Santé et Recherche Médicale U1015, and Scientific Director of the Immuno-Oncology programmm at Gustave Roussy, the largest cancer Center in Europe. She has been actively contributing to the field of cancer immunology and immunotherapy, and she brought together basic and translational research, including the design of cancer therapies through combined animal studies and Phase I patient trials. Her expertise is mainly dendritic cell and innate effector biology and relevance during tumour development as well as exosome-based vaccine designs. She pioneered the concept of immunogenic cell death and showed that chemotherapy, radiotherapy and inhibitors of tyrosine kinase mediate their tumoricidal activity, at least partly through the immune system. Her team discovered the critical role and impact of gut microbiota in cancer immunosurveillance and therapies. He was the recipient of many awards including the National Academy of Medicine, the Translation Research INSERM Prize, the ASCO-SITC award 2017 and the Brupbacher Award.

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Thaddeus Stappenbeck

professor
Washington University School of Medicine, St. Louis

Thaddeus S. Stappenbeck M.D., Ph.D.
Professor
Department of Pathology and Immunology
Washington University School of Medicine
Saint Louis, Missouri 63110

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Cathryn Nagler

Professor
University of Chicago

Cathryn R. Nagler is the Bunning Food Allergy Professor and Professor of Pathology, Medicine, Pediatrics and The College at The University of Chicago. She graduated with honors from Barnard College, Columbia University, obtained her Ph.D. from the Sackler Institute of Biomedical Science at N.Y.U. School of Medicine and did a postdoctoral fellowship at the Massachusetts Institute of Technology. She was Associate Professor of Pediatrics (Immunology) at Harvard Medical School prior to joining the University of Chicago in 2009. Dr. Nagler has participated in numerous review panels for the Crohn’s and Colitis Foundation of America, NIDDK and NIAID, including the Food Allergy Expert Panel. She has served the American Association of Immunologists as Section Editor for the Journal of Immunology, Instructor (Mucosal Immunology) for the Introduction to Immunology course and as member of the Program, Clinical Immunology, Publications and Awards Committees. Dr. Nagler has a long-standing interest in the mechanisms governing tolerance to dietary antigens and the potential immunomodulatory features of this route of antigen administration. Her most recent work examines how intestinal bacteria regulate susceptibility to allergic responses to food. In 2016 Dr. Nagler co-founded ClostraBio, a new company dedicated to developing novel microbiome-modulating therapeutic interventions for the prevention and treatment of food allergy.

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Microbiome/Immune Interactions



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