Plenary

T Cell Subsets and Their Responses to Pathogens and Autoantigens

Thursday, June 15
8:00 AM - 9:30 AM

Sponsored By: 

Elaine F. Reed

University of California Los Angeles

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Daniel L. Mueller

Professor and Director Rheumatic and Autoimmune Diseases
University of Minnesota Medical School

Professor and Director of Rheumatic and Autoimmune Diseases
University of Minnesota Medical School
Dates Employed 1992 – Present Employment Duration 25 yrs

Autoimmune Diseases Research Principal Investigator
Professor in PhD-Level Immunology Instruction
Rheumatology Clinical Care and Training

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Vijay K. Kuchroo

Samuel Wasserstrom Professor of Neurology
Harvard Medical School, Brigham & Women's Hospital

Dr. Vijay Kuchroo is the Samuel L. Wasserstrom Professor of Neurology at Harvard Medical School. Vijay Kuchroo is also an associate member of the Broad Institute and a participant in a Klarman Cell Observatory project that focuses on T cell differentiation. He was just named the Director of the newly formed Evergrande Center for Immunologic Diseases at Harvard Medical School and Brigham and Women’s Hospital. His major research interests include autoimmune diseases and cancer. Dr. Kuchroo first described the inhibitory receptor TIM-3, which is being exploited as a target for cancer immunotherapy. He was aslo first to describe the development of highly pathogenic Th17 cells. He has published over 325 original research papers in the filed of Immunology and a paper describing development of Th17 authored by Dr. Kuchroo has been one of the highest cited papers in Immunology.

He obtained his degree in Veterinary Medicine from India and subsequently he specialized in pathology at the University of Queensland, Brisbane (Australia) where he obtained a Ph.D. in 1985. He received the Fred Z. Eager Research prize and medal for his Ph.D. research work at the University of Queensland. Based on his contributions, he was awarded the Javits Neuroscience Award by the National Institutes of Health in 2002 and the Ranbaxy prize in Medical Research from the Ranbaxy Science Foundation in 2011. He was named Distinguished Eberly lecturer in 2014 and obtained Nobel Laureate Peter Doherty lecture/prize in 2014.

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Federica Sallusto

Director Center of Medical Immunology
Institute for Research in Biomedicine, Università della Svizzera italiana

Federica Sallusto is Head of the Cellular Immunology Laboratory and Director of the Center of Medical Immunology at the Institute for Research in Biomedicine, Università della Svizzera italiana, Bellinzona, Switzerland. Since February 2017, she is also Professor of Medical Immunology at the ETH Zurich. She is expert in the field of human cellular immunology. Her main contributions deal with mechanisms that regulate migration and effector function of T lymphocytes. These studies allowed to define Th1, Th2, Th17 and Th22 cells on the basis of chemokine receptor expression and to distinguish central and effector memory T cells. Recently, she clarified mechanisms that generate Th17 lymphocytes with different inflammatory capacity and demonstrated that, within a single clone, T cells can acquire different functional properties.

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