Member Society Symposia

Immune Cells as Therapies

Wednesday, June 14
12:45 PM - 3:30 PM

Sponsored By: Center for International Blood and Marrow Transplant Research (CIBMTR)

The field of adoptive cellular therapies is now entering the mainstream of clinical care for patients with cancer. Genetically modified T cells were first developed in the academic setting, and following the initial reports of remarkable efficacy, cell therapies are now being commercially developed for various cancer indications. This symposium will review how genetically modified T cells are designed and manufactured, and the clinical data for their use in B cell malignancies, other hematologic malignancies, and solid tumors. The clinical administration of cell therapies can be complex and requires a multidisciplinary approach. The first cell therapies are expected to be enter the market in 2017, when CD1-directed chimeric antigenreceptor-modified T cells are expected to be approved as therapy for advanced B-cell leukemias and lymphomas. There are also potential uses for immune cell therapies in other hematologic malignancies, and there are ongoing clinical investigations with immune cells re-directed to solid tumors. Education of physicians and immunologists is necessary for the successful, safe, and efficacious implementation of these novel and exciting therapies.




Chair:
Marcela Maus, MD, PhD, Massachusetts General Hospital

Agenda:
12:45 p.m. Introduction
Marcela Maus, MD, PhD, Massachusetts General Hospital

1:00 p.m. Update on CD19 CAR T cells in B cell Malignancies
Stephan Grupp, MD, PhD, Children's Hospital of Philadelphia

1:30 p.m. CAR T cells in Non-b cell Hematologic Malignancies
Marcela Maus, MD, PhD, Massachusetts General Hospital/Harvard Medical School

2:00 p.m. CAR T Cells in Solid Tumors
Prasad Adusumilli, MD, PhD, Memorial Sloan Kettering Cancer Center

2:30 p.m. Managing complications of CAR T cell therapies
Sarah Nikiforow, MD, PhD, Dana Farber Cancer Institute

3:00 p.m. Q&A
Panel Discussion

Learning Objectives:


Assets

Immune Cells as Therapies



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