Category: Autoimmune rheumatologic diseases

T.11 - cd11b Activation Protects Against Lupus Nephritis by Suppressing Tlr-dependent Ifn Responses

Thursday, Jun 15
5:45 PM – 7:00 PM

Mehmet Altintas

Rush University Medical Center
Chicago, Illinois

Mohd. Hafeez Faridi

Assistant Professor
Rush University Medical Center
Chicago, Illinois

Vineet Gupta

Professor and Vice Chair for Research and Innovation, Department of Internal Medicine
Rush University Medical Center
Chicago, Illinois

Mariana J. Kaplan

Senior Investigator and Chief, Systemic Autoimmunity Branch
National Institute of Arthritis and Musculoskeletal and Skin Diseases/National Institutes of Health
Bethesda, Maryland

Mariana J. Kaplan, MD is Senior Investigator and Chief of the Systemic Autoimmunity Branch at the National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health. Dr. Kaplan's research has focused on identifying mechanisms of organ damage and premature vascular disease in systemic autoimmunity. More specifically, she investigates how innate immunity promotes end-organ damage in systemic lupus erythematosus, rheumatoid arthritis and other systemic autoimmune diseases. Recently, her research has focused on identifying abnormalities of neutrophil subsets and the role of neutrophil extracellular traps (NETs) in lupus, vasculitis and rheumatoid arthritis, both of which may contribute to the development of autoimmune responses and to end-organ damage. Dr. Kaplan also has an interest in identifying novel therapeutic targets that may prevent premature vascular damage in systemic autoimmunity, as well as the role of environmental triggers in the induction of autoimmunity. Moreover, she has led clinical trials to identify mechanisms that reduce blood vessel dysfunction in autoimmune and chronic inflammatory disorders.

HaWon Lee

Postdoctoral Research Fellow
Rush University Medical Center
Chicago, Illinois

Wenpu Trim

Research Fellow
NIAMS/NIH
Bethesda, Maryland

Samia Q. Khan

Postdoctoral Research Fellow
Rush University Medical Center
Chicago, Illinois