Podium Session

Poster, Podium & Video Sessions

PD12-12: Evaluation of Surface Micropattern (Sharklet) on Foleys Silicon Catheter in reducing Urinary Tract Infections

Friday, May 12
5:20 PM - 5:30 PM
Location: BCEC: Room 159

Presentation Authors: Vinodh Kumar Adithyaa Arthanareeswaran*, Andras Magyar, Lila Soos, Bela Koves, Abinaya Ravichandran Chandra, Budapest, Hungary, Nora Justh, Imre Miklos Szilagyi, Budapest , Hungary, Tenke Peter, Budapest, Hungary

Introduction: Catheter-associated urinary tract infection (CAUTI) is a major preventable cause of harm in hospitalized patients. Previous in vitro studies have shon wthat a unique surface micropattern on catheter surface reduces bacterial biofilm formation. This single center, open labelled, randomized interventional study evaluated if the Sharklet micropatterned catheter (SC) reduces UTI in catheterized patients, when compared to a standard silicone Foley catheter. (NCT02835456)

Methods: Fifty eligible adult men requiring temporary urethral catheterization for a period between 3 and 30 days were randomized into two groups with standard silicone Foley catheter insertion in one and SC in other. On removal, parts of the catheters (tip, middle part and base) were examined for bacterial colonization/biofilm using scanning electron microscopy. The patients were also assessed for incidence of symptomatic UTI, significant asymptomatic bacteriuria, pain and discomfort.

Results: The mean age and duration of catheterization were similar among both groups. None of the patients developed symptomatic CAUTI. The outer surface of the SC had significantly lower biofilm formation when compared to the standard silicone catheter in all parts of the catheter (Tip: P= 0.003, Middle part: P=0.013 and Base: P=0.013). However, this difference was not noted in the inner surface of the catheters (P= 0.511, P=0.245, P=0.810 respectively); which may be attributed to the absence of micropattern in the inner surface of SC. There was significantly lower pain and discomfort in patients using SC when compared to the standard catheter (p=0.018).

Conclusions: Catheters that can reduce CAUTI have the advantage of improving the care of millions of disabled and elderly patients and reducing the enormous costs of managing complications associated with indwelling Foley catheter. However, none of the numerous strategies tested until now, like antibiotic or silver impregnation on catheter surface have proved to be useful in this regard. This is the first trial to test the efficacy of Sharklet micropattern on urinary catheter surface in a clinical setting. The promising results of this study opens the arena for novel mechanical modifications on catheter surface which may be both cost effective and clinically beneficial.

Source Of Funding: None

Vinodh Kumar Adithyaa Arthanareeswaran, MS

Jahn Ferenc South Pest Teaching Hospital

Dr. Vinodh Kumar Adithyaa Arthanareeswarran is a urologist at Department of urology, University Leipzig, Germany. He attended Madurai Medical College and trained in surgery at Silchar Medical College in India. He pursued fellowship training at Jahn Ferenc South Pest Teaching Hospital, Budapest, Hungary, studying laparoscopic urological surgery. His clinical interests include urological malignancies. His basic science research is focussed on urological infecctions and immunotherapy.


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PD12-12: Evaluation of Surface Micropattern (Sharklet) on Foleys Silicon Catheter in reducing Urinary Tract Infections



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