Category: Treatment - CBT
Keywords: Stress | Clinical Trial | Exposure
Presentation Type: Symposium
Dr. Sloan will lead off the symposium by presenting the primary treatment outcome findings for the non-inferiority randomized controlled trial. She will present findings of whether the brief, 5 session exposure-based treatment referred to as Written Exposure Therapy (WET) is equally efficacious in the treatment of PTSD compared with Cognitive Processing Therapy (CPT), a first-line PTSD treatment that consists of a greater treatment dose than WET. A secondary goal of the study is to examine whether treatment dropout rates are significantly lower for WET relative to CPT. Assessments took place at baseline, 6-, 12,-, 24-, and 36-weeks post first treatment session. The primary treatment outcome measure is PTSD symptom severity assessed using the Clinician-Administered PTSD Scale for DSM-5 (CAPS-5). Assessments were conducted by a master’s or doctoral level psychologist who was blinded to treatment condition assignment. A total of 126 adults diagnosed with PTSD were randomly assigned to either CPT (n=63) or WET (n=63). The sample has a mean age of 44.02 (SD -14.1), 52% are men, and the sample is racially diverse with 50% identifying as White. Using an intent to treat approach, all individuals randomized were followed at each of the assessments. Although the follow up phase is ongoing, our retention rate for the follow up assessments is no lower than 85%. As the assessment phase is ongoing we cannot report outcome findings at this time. We will examine whether WET is equally efficacious (i.e., non-inferior) relative to CPT at each of the assessments (6-,12-, 24- and 36-weeks). We can report the second goal of the study which was to investigate whether WET is more tolerable (e.g., associated with a lower treamtent dropout rate) relative to CPT. As predicted, significantly more individuals dropped out of CPT prematurely (38%) relative to WET (6%). The majority of participants dropped out of CPT within the first 5 sessions with the majority of participants reporting reason for dropout as difficulty tolerating CPT. We expect to find that WET is a promising alternative treatment that will address many of the cited barriers to both receiving PTSD treatment as well as implementing evidence-based PTSD treatment.
National Center for PTSD, VA Boston Healthcare System
Friday, November 17
3:30 PM – 5:00 PM
Friday, November 17
5:15 PM – 6:15 PM
Saturday, November 18
3:30 PM – 4:30 PM
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