Category: Neuroscience

Panel Discussion

Panel Discussion 9 - You Will Get Better and You Won’t: Using Brain Imaging and Biomarkers to Predict Treatment Response

Friday, November 17
1:45 PM - 3:15 PM
Location: Aqua Salon C & D, Level 3, Aqua Level

Keywords: Neuroscience | Translational Research | Psychotherapy Outcome
Presentation Type: Panel Discussion

While cognitive-behavioral therapy (CBT) is now generally considered to be the treatment of choice for most psychological disorders, a significant proportion of patients treated using CBT fail to benefit from the treatment. As such, the question that researchers and clinicians alike now face is not whether CBT is effective, but rather whether we can predict who will respond to CBT and who will not. Despite our best efforts over the years, few reliable predictors of treatment outcome have been identified. One explanation for this is that psychological disorders are, in fact, really heterogeneous conditions with variable responses to a wide range of treatments. In recent years, however, our understanding of the relationship between psychological disorders and brain structure and function has grown rapidly, with emerging data suggesting that neuroimaging can in fact provide pre-treatment biomarkers that are sufficiently accurate to improve predictions for the response (and in some cases, the non-response) of CBT, and even the differential response to CBT and pharmacotherapy. If these preliminary results hold true, it would suggest that such biomarkers might offer insight into the mechanisms of psychological treatment as well as an evidence-based, personalized medicine approach that could be applied in clinical practice for optimally selecting among treatment options for a patient. As such, in this panel discussion, four experts will consider these and other ways in which neuroimaging and biomarkers might be used to detect changes and predict treatment response to CBT for Depression (Ed Craighead), Social Anxiety Disorder (Stefan Hofmann), Posttraumatic Stress Disorder (Barbara Rothbaum), and Obsessive-Compulsive Disorder (David Tolin).

Learning Objectives:

Ed Craighead

J. Rex Fuqua Professor, Department of Psychiatry and Behavioral Sciences and Department of Psychology
Emory University

Presentation(s):

Send Email for Ed Craighead

Send Email for Stefan Hofmann

Barbara Rothbaum

Professor of Psychiatry
Emory University School of Medicine

Presentation(s):

Send Email for Barbara Rothbaum

Send Email for David Tolin

Send Email for Simon Rego


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