Successfully regulating emotions is essential for our adaptive functioning and well-being. Among emotion regulation strategies, emotion suppression is generally known as a maladaptive regulatory strategy that is often used when one experiences negative affect. Due to particular job characteristics, there are environments that require emotion suppression, in particular suppression of negative affect such as anger. Recently, as interests in emotional laborers increase, the necessity of conducting research on emotional labor experienced by nurses has become inevitable. Nursing involves emotional caring that requires a balance of emotional engagement and detachment, demanding much emotional labor as medical service in hospitals is emphasized presently. Current studies report that nurses have higher anger tendencies and stress than other professions. Thus, this study examined the effects of emotional labor and stress on anger suppression in Korean nurses. Participants consisted of 98 Korean nurses aged 20-39 years working at a university hospital. They were instructed to complete self-report questionnaires that consisted of Korean Emotional Labor Scale (KELS) for emotional labor, Korean Occupational Stress Scale-Short Form (KOSS-SF) to measure stress, and Korean State-Trait Anger Expression Inventory (STAXI-K) to assess degree of anger suppression. Hierarchical multiple regressions were conducted to determine the meditational effect of stress on the relationship between emotional labor and anger suppression. Results indicated that degree of emotional labor was a significant predictor of anger suppression, and that stress fully mediated the relationship. These findings suggest that high emotional labor in nurses is associated with suppressing anger, and that addressing occupational stress may be useful in adaptively managing nurses’ experience of negative affect for nursing.