Full Schedule
7:30 AM - 5:00 PMRegistration Open
- 8:30 AM - 4:30 PMSaturday Short CoursesShort Courses
8:30 AM - 4:30 PM3D Cell-Based Assays for Drug De-Risking Ursula Graf-Hausner – Zurich University of Applied Sciences ### 62414###Short Course Instructor - Funded @@@ Jens M. Kelm, Ph.D – InSphero AG ### 43392###Short Course Instructor - Funded
8:30 AM - 4:30 PMGetting Started with Excel & VBA in the Laboratory (2-Day) Martin Echols – EcholsTech ### 62409###Short Course Instructor - Funded @@@ William Neil – BMS ### 62427###Short Course Instructor - Funded
8:30 AM - 4:30 PMIntroduction to Laboratory Automation James Gill, II. – BMS ### 62413###Short Course Instructor - Funded @@@ Steve Hamilton – SLAS ### 62416###Short Course Instructor - Funded
8:30 AM - 4:30 PMLab-on-a-Chip: From Technology to Bioanalysis on Chip Jorg P. Kutter, PhD, M.Sc. – University of Copenhagen ### 62423###Short Course Instructor - Funded @@@ Johan Nilsson – Lund University ### 62429###Short Course Instructor - Funded @@@ Sabeth Verpoorte – Groningen Research Institute of Pharmacy University of Groningen ### 62436###Short Course Instructor - Funded
8:30 AM - 4:30 PMMultiparametric Analysis of Scientific Image Data (NEW!) Marc Bickle, Dr. – MPI-CBG ### 61272###Short Course Instructor - Funded @@@ Antje Janosch ### 185947###Short Course Instructor - Funded
8:30 AM - 5:30 PMAssay Guidance Workshop for High Throughput Screening and Lead Discovery Terry L. Riss, PhD – Promega Corporation ### 62431###Presenter @@@ Lisa Minor, PhD – In Vitro Strategies, LLC ### 43412###Presenter @@@ G. Sitta Sittampalam, PhD – NIH/NCATS ### 119623###Short Course Instructor - Not Funded @@@ Douglas Auld, PhD – Novartis ### 62440###Presenter @@@ Michelle R. Arkin, PhD – Department of Pharmaceutical Chemistry, School of Pharmacy, University of California, San Francisco ### 61294###Presenter @@@ Viswanath Devanarayan, Ph.D – AbbVie, Inc. ### 187861###Short Course Instructor - Funded @@@ Thomas D.Y Chung, PhD – Mayo Clinic ### 72744###Short Course Instructor - Not Funded @@@ Menghang Xia ### 187863###Short Course Instructor - Funded @@@ Xin Xu ### 187864###Short Course Instructor - Funded @@@ Nathan P. Coussens, PhD – National Center for Advancing Translational Sciences, National Institutes of Health ### 187865###Short Course Instructor - Not Funded
- 8:30 AM - 4:30 PMSunday Short CoursesShort Courses
8:30 AM - 4:30 PMAffinity-Based, Biophysical Methods for Screening and Mechanistic Studies Christine C. Genick, Dr. – Novartis ### 62412###Short Course Instructor - Funded @@@ Stefan Geschwindner – Discovery Sciences, AstraZeneca R&D Mölndal ### 185943###Short Course Instructor - Funded
8:30 AM - 4:30 PMCross Functional Project Management for Technical Professionals Barry M. Weinstein – Barry M. Weinstein and Associates ### 119627###Short Course Instructor - Funded
8:30 AM - 4:30 PMData Management in the Age of Big Data, Mobile, and the Cloud Burkhard Schaefer – BSSN Software ### 62433###Short Course Instructor - Funded
8:30 AM - 4:30 PMDerivation of iPS Cells and Maintenance Techniques of iPS-Derived Cells for Use in High-Throughput Screening and Disease Modeling David J. Kahler, PhD PMP – NYU Langone Medical Center RNAi Core Facility ### 43236###Short Course Instructor - Funded @@@ Kamal Garcha – GFY Biotech Consulting ### 187280###Short Course Instructor - Funded
8:30 AM - 4:30 PMDigital Image Processing and Analysis for the Laboratory Scientist: Theory and Application (Laptop Required) Matthew Fronheiser – Bristol-Myers Squibb ### 119610###Short Course Instructor - Funded @@@ Mark Russo – Bristol-Myers Squibb ### 62432###Short Course Instructor - Funded
8:30 AM - 4:30 PMEstablishing Cell-Based Assays for Screening Geoffrey Bartholomeusz, PhD – University of Texas MD Anderson Cancer Center ### 62406###Short Course Instructor - Not Funded @@@ Eric N. Johnson – Wuxi AppTec ### 185948###Short Course Instructor - Funded @@@ Lisa Minor, PhD – In Vitro Strategies, LLC ### 43412###Short Course Instructor - Funded @@@ Terry L. Riss, PhD – Promega Corporation ### 62431###Short Course Instructor - Funded
8:30 AM - 4:30 PMGetting Started with Excel & VBA in the Laboratory (2-Day) Martin Echols – EcholsTech ### 62409###Short Course Instructor - Funded @@@ William Neil – BMS ### 62427###Short Course Instructor - Funded
8:30 AM - 4:30 PMHigh Content Screening: An Introduction to Instrumentation, Assay Development, Screening, Image and Data Analysis (NEW!) Steffen Jaensch ### 185946###Short Course Instructor - Funded @@@ Eberhard Krausz – ChemBioCon ### 62422###Short Course Instructor - Funded
8:30 AM - 4:30 PMLab-on-a-Chip: Case Studies in Diagnostics and Screening (NEW!) Jorg P. Kutter, PhD, M.Sc. – University of Copenhagen ### 62423###Short Course Instructor - Funded @@@ Johan Nilsson – Lund University ### 62429###Short Course Instructor - Funded @@@ Sabeth Verpoorte – Groningen Research Institute of Pharmacy University of Groningen ### 62436###Short Course Instructor - Funded
8:30 AM - 4:30 PMLiquid Handling Essentials (Interactive Course) Dana Campbell – Artel ### 72843###Short Course Instructor - Funded @@@ Nathaniel Hentz – NC State University BTEC ### 43375###Short Course Instructor - Funded @@@ Lisa Knapp ### 185950###Short Course Instructor - Funded
8:30 AM - 4:30 PMNext Generation Sequencing Technology Fundamentals and Applications Dawei Lin, PhD – NIH/NIAID ### 62425###Short Course Instructor - Funded @@@ Abizar Lakdawalla, PhD – Thermo Fisher Scientific ### 187496###Short Course Instructor - Funded
8:30 AM - 4:30 PMSample Management: Best Practice, Trends and Challenges Sue Crimmin, Bsc PhD – GSK ### 43275###Short Course Instructor - Funded @@@ Kathi E. Shea, BS – Precision for Medicine ### 62434###Short Course Instructor - Funded
8:30 AM - 12:00 PMScreening Strategies for Drug Discovery: Matching Tools with Solutions (Half-Day Course) Jonathan Lee ### 185951###Short Course Instructor - Funded @@@ David C. Swinney, PhD – Institute for Rare and Neglected Diseases Drug Discovery ### 61363###Short Course Instructor - Funded
8:30 AM - 4:30 PMStudy Design and Statistical Analysis for High Throughput Screening (HTS) Experiments (NEW!) Robert Nadon – Department of Human Genetics, McGill University McGill University and Genome Quebec Innovation Centre ### 119617###Short Course Instructor - Funded
1:30 PM - 4:30 PMGene Editing for Drug Discovery (Half-Day Course)
John G. Doench – Broad Institute of MIT and Harvard ### 184220###Short Course Instructor - Funded @@@ Samuel A. Hasson, PhD – Pfizer Neuroscience ### 185944###Short Course Instructor - FundedSponsored By:
1:00 PM - 4:30 PMTechnology to Propel Science: GNF Automation Tour and Seminar
5:30 PM - 7:00 PMSLAS Student and Early Career Professionals Event at Tin Roof
6:30 AM - 7:30 AM2016 SLAS FUNd Run
Sponsored By:
7:00 AM - 8:00 AMCANCELED: Laboratory Products Association (LPA) Special Session
7:30 AM - 8:30 AMThe Negotiation Process – Learn how to motivate others to achieve win-win solutions; Dan Eustace, PhD, University of Connecticut
7:30 AM - 6:00 PMRegistration Open
8:00 AM - 8:30 AMMorning Beverage Break
8:00 AM - 5:00 PMSpeaker Ready Room Open
8:30 AM - 9:00 AMKeynote Session: Welcome and Opening Remarks
9:00 AM - 10:00 AMKeynote: Analyzing the Complexity of Drug Resistance in Cancer Michael Gottesman, MD ### 185756###Keynote Speaker
10:00 AM - 10:30 AMBeverage Break in the Exhibit Hall
10:00 AM - 6:30 PMExhibition Open
10:00 AM - 6:30 PMPosters on Display in Exhibition
10:00 AM - 6:30 PMSLAS Member Center
10:30 AM - 12:30 PM2016 SLAS Leadership Forum (Invitation Only)
- 10:30 AM - 12:30 PMAutomating Phenotypic and Target Based Discovery Using Parallel Automated ApproachesAutomation & High Throughput Technologies
10:30 AM - 11:00 AMFully Automated 3D Cell Culture Provides Standardized, Biologically Relevant, and High Production for Human Cells Robin A. Felder, PhD – The University of Virginia ### 184282###Speaker - Funded
11:00 AM - 11:30 AMFully Automated and Integrated Approaches Identify Novel Modulators of Xenobiotic Receptors PXR and CAR Taosheng Chen, PhD – St. Jude Children's Research Hospital ### 185938###Session Chair & Speaker - No Funding
11:30 AM - 12:00 PMHigh-throughput Screening Using BOK-mediated Apoptotic Assay Identifies Novel Proteasome Inhibitors Against Human Cancer Yueming Wang, PhD – High Throughput Screening Center, Chemical Biology and Therapeutics, St. Jude Children's Research Hospital ### 184260###Speaker - Not Funded
12:00 PM - 12:30 PMAddressing the Challenges of 1536 Cell Based Screening Helen Plant – AstraZeneca Pharmaceuticals ### 142438###Speaker - Not Funded
- 10:30 AM - 12:30 PMBiochemical and Biophysical Screening AssaysAssay Development & Screening
10:30 AM - 11:00 AMImpact of Biophysical Approaches Immediately Post HTS in Aiding Hit Confirmation Activities Jarrod Walsh, Mr – AstraZeneca ### 184200###Speaker - Not Funded
11:00 AM - 11:30 AMFragment Screening with Biodesy’s Second Harmonic Generation Platform for Detecting Ligand-induced Changes in Protein Conformation Charles Wartchow, PhD – Novartis Institutes for Biomedical Research ### 184252###Speaker - Not Funded
11:30 AM - 12:00 PMDiscovery and Development of Inhibitors of the De Novo Purine Biosynthetic Enzyme PAICS – from Fragments to Lead Compounds Peter Coombs – MRC Technology ### 184230###Speaker - Not Funded
12:00 PM - 12:30 PMSmall Molecule Inhibition Amenability of Nucleotide Pyrophosphatases Involved in DNA Repair - From MTH1 to dUTPase Thomas Lundbäck – Chemical Biology Consortium Sweden, Science for Life Laboratories, Karolinska Institutet ### 78046###Session Chair & Speaker - No Funding
- 10:30 AM - 12:30 PMBiomarkers and Translational SciencesAdvances in Bioanalytics, Biomarkers and Diagnostics
10:30 AM - 11:00 AMMPseq Is a Whole Genome Sequencing Platform That Has Been Used to Develop Biomarker Tests George Vasmatzis – Biomarker Discovery, Center for Individualized Medicine, Mayo Clinic ### 184296###Speaker - Funded
11:00 AM - 11:30 AMEnabling Deep Tissue Proteomics with Limited Prefractionation Harsha Gunawardena – Amgen Inc ### 184298###Speaker - Not Funded
11:30 AM - 12:00 PMImplementation of Commercial Glucometer in Detection of Melanoma Nucleic Acid Biomarkers Armin Nourani – The University of Texas at Austin ### 123188###Speaker - Tony B. Awardee
12:00 PM - 12:30 PMDevelopment and Validation of an Assay to Detect Mutant Huntingtin Protein for the Assessment of Pharmacodynamic Effects in Human and Rodent Samples Alberto Bresciani – IRBM Science Park SpA ### 61249###Speaker - Not Funded
10:30 AM - 12:30 PMCareer Connections: Mentoring Sessions / One-on-One Career Counseling Sessions / Job Boards
- 10:30 AM - 12:30 PMDigital and Droplet MicrofluidicsMicro/Nano Technologies
10:30 AM - 11:00 AMDroplet Microfluidics: Amphiphilic Nanoparticles as Droplet Stabilizers for High-fidelity and Ultrahigh-throughput Droplet Assays Sindy KY. Tang – Stanford University ### 184225###Session Chair & Speaker - WITH Funding
11:00 AM - 11:30 AMThiol-ene Based Microreactors for Protein Digestion and Peptide Mapping Alexander Jönsson – University of Copenhagen ### 184201###Speaker - Tony B. Awardee
11:30 AM - 12:00 PMRNA-Seq Following PCR-activated Cell Sorting (PACS) Reveals Rare Cell Transcriptional Signatures Dennis J. Eastburn – Mission Bio, Inc. ### 184271###Speaker - Not Funded
12:00 PM - 12:30 PMNano-Droplet Array Plates (nDAPs): Detection of IFNγ-expressing Cells in Circulating PBMCs Immobilized in Nano-gel Arrays Alan M. Lyons – ARL Designs LLC ### 184236###Speaker - Not Funded
- 10:30 AM - 12:30 PMMachine Learning to Optimize ExperimentsInformatics
10:30 AM - 11:00 AMWhy Have One Model When You Could Have Thousands? Alex M. Clark, Ph.D. – Molecular Materials Informatics ### 184216###Session Chair & Speaker - No Funding
11:00 AM - 11:30 AMThe Visual Assay™ Platform: A Novel Mobile Assay Workflow and Project Management Tool to Ensure Data Reproducibility - Using Mobile Devices in the Lab to Capture & Share Assay Data Mannix Aklian – Label Independent, Inc ### 184226###Speaker - Not Funded
11:30 AM - 12:00 PMFrom out That Shadow: Diagnosis, Discovery, and Data Integration in Single Cell Phenomics Michael D. Stadnisky, Ph.D. – FlowJo, LLC ### 119491###Speaker - Not Funded
12:00 PM - 12:30 PMMining Cellular Heterogeneity for Mechanistic Insights in Phenotypic Profiling and Drug Discovery Albert H. Gough – University of Pittsburgh ### 184273###Speaker - Not Funded
11:00 AM - 5:30 PMSLAS2017 Exhibitor Space Draw
- 12:30 PM - 1:15 PMExhibitor TutorialExhibitor Tutorial
12:30 PM - 1:15 PMArtel Exhibitor Tutorial: Introducing New Technology for Liquid Handling Quality Assurance Kerry Fairlie ### 193536###Exhibitor Tutorial Organizer @@@ John T. Bradshaw, PhD – Artel ### 184708###Exhibitor Tutorial Presenter @@@ Bill Gigante – STRATEC BIOMEDICAL USA ### 43269###Exhibitor Tutorial Presenter
12:30 PM - 1:15 PMBMG LABTECH Exhibitor Tutorial: Monitoring GPCR ligand binding using NanoBRET detected with BMG LABTECH microplate readers Carl Peters – BMG LABTECH ### 45027###Exhibitor Tutorial Organizer @@@ Kevin Pfleger, PhD – Harry Perkins Institute of Medical Research and The University of Western Australia ### 193538###Exhibitor Tutorial Presenter
12:30 PM - 1:15 PMNanion Technologies Exhibitor Tutorial: Dr. Jun Chen, Senior Scientist Genentech presents James Costantin ### 186763###Exhibitor Tutorial Organizer @@@ Jun Chen ### 194053###Exhibitor Tutorial Presenter
12:30 PM - 1:15 PMPerkinElmer Exhibitor Tutorial: Alpha SureFire® Ultra™ Multiplex: Rapid Homogeneous Detection Systems for Cellular Signaling Pathways Pam Clemens ### 186764###Exhibitor Tutorial Organizer
12:30 PM - 1:15 PMThermo Fisher Scientific Exhibitor Tutorial: GeneArt Arrayed Lentiviral CRISPR Library as Powerful High-Throughput Loss-of-Function Screening Tools Christa Lamps ### 188845###Exhibitor Tutorial Organizer @@@ Jian-Ping Yang – Thermo Fisher Scientific ### 198651###Exhibitor Tutorial Presenter
12:30 PM - 1:15 PMTTP Labtech Exhibitor Tutorial: Use of Fluorescence Lifetime Technologies for High-Throughput Protein Kinase Screening and Profiling Dawn Browning ### 184722###Exhibitor Tutorial Organizer @@@ Graham Cotton – Almac Group ### 43264###Exhibitor Tutorial Presenter
12:30 PM - 1:30 PMLunch in the Exhibition Hall
- 12:30 PM - 1:45 PMExhibitor TutorialExhibitor Tutorial
12:30 PM - 1:45 PMBrooks Automation Exhibitor Tutorial: Advancing Compound Collections and Technologies in the Quest of a Hit for Every Target Sue Jones ### 198664###Exhibitor Tutorial Organizer @@@ David Lewandowski ### 184712###Exhibitor Tutorial Presenter @@@ Clive Green – AstraZeneca ### 184212###Exhibitor Tutorial Presenter
12:30 PM - 1:45 PMIntelliCyt Corporation Exhibitor Tutorial: Nimble Meets Quick: True Immunology Screening with the Only True High Throughput Flow Platform Petra Donnelly ### 184715###Exhibitor Tutorial Organizer @@@ Ben Hoffstrom – Fred Hutch Cancer Research Center ### 184294###Exhibitor Tutorial Presenter @@@ Mark Fereshteh – Bristol Myers Squibb ### 198629###Exhibitor Tutorial Presenter @@@ Mark Wigglesworth – AstraZeneca - Discovery Sciences ### 119521###Exhibitor Tutorial Presenter @@@ Joseph Zock – IntelliCyt Corporation ### 198630###Exhibitor Tutorial Presenter
12:30 PM - 1:45 PMLabcyte Inc. Exhibitor Tutorial: Advancing Scientific Innovation with Acoustic Droplet Ejection─Author Presentations from JALA Special Issue Valerie Weld – Labcyte Inc. ### 184716###Exhibitor Tutorial Organizer @@@ Maureen Beresini – Genentech ### 198567###Exhibitor Tutorial Presenter @@@ Lynn Rasmussen – Southern Research Institute ### 198571###Exhibitor Tutorial Presenter @@@ Kristin Blom – Uppsala University ### 198569###Exhibitor Tutorial Presenter @@@ Colin Cox – Genentech ### 43350###Exhibitor Tutorial Presenter
12:30 PM - 1:45 PMThermo Fisher Scientific Exhibitor Tutorial: Capture Diverse Workflows in Screening, Synthetic Biology and Clinical Genomics Jeanette Minshall ### 184721###Exhibitor Tutorial Organizer @@@ Huimin Zhao, Ph.D – University of Illinois, Urbana-Champaign (UIUC) ### 194011###Exhibitor Tutorial Presenter @@@ Alexander Wolf, Ph.D – Lead Discovery Center ### 72738###Exhibitor Tutorial Presenter @@@ Robyn Loverro, M.S. – Genomic Health ### 194291###Exhibitor Tutorial Presenter
12:30 PM - 2:00 PMLeadership Forum: Networking Lunch (Invitation Only)
12:30 PM - 2:30 PMBeckman Coulter Life Sciences Exhibitor Tutorial: Advancing Disease Understanding by Automation Donna Gorman ### 184709###Exhibitor Tutorial Organizer @@@ Ana Kitanovic – German Center for Neurodegenerative Diseases (DZNE), Bonn ### 195141###Exhibitor Tutorial Presenter @@@ Jan M. Bruder – Max Planck Institute for Molecular Biomedicine ### 188020###Exhibitor Tutorial Presenter
12:45 PM - 1:45 PMSLAS Special Update: Europe Region
1:00 PM - 1:30 PMJALA/JBS VIP Meet & Greet: Meet JALA Editor-in-Chief Edward Kai-Hua Chow, PhD (National University of Singapore)
1:00 PM - 2:00 PMNegotiating Work and Life— Stay happy on and off the job with “Kamens’ Ten Commandments of Work/Life Balance; Joanne Kamens, Ph.D. Executive Director, Addgene
1:00 PM - 3:00 PMPoster Presentations (Odd Numbered Posters)
1:30 PM - 2:00 PMJALA/JBS VIP Meet & Greet: "Development of a Highly Sensitive Cell-Based Assay for Detecting Botulinum Neurotoxin Type A through Neural Culture Media Optimization" with JBS Author David Beebe of the Univ. of Wisconsin
2:00 PM - 2:30 PMJALA/JBS VIP Meet & Greet: "Advancing Scientific Innovation with Acoustic Droplet Ejection" with JALA Special Issue Guest Editor Joe Olechno of Labcyte
- 2:00 PM - 2:45 PMExhibitor TutorialExhibitor Tutorial
2:00 PM - 2:45 PMCellular Dynamics International Exhibitor Tutorial: Driving Diabetes-related Research Through Pathway Dissection of Human iPSC-derived Cell Models Marissa Stafford ### 191357###Exhibitor Tutorial Organizer @@@ Coby B. Carlson, PhD – Cellular Dynamics International ### 44636###Exhibitor Tutorial Presenter
2:00 PM - 2:45 PMEppendorf Exhibitor Tutorial: Presentation Title to Be Announced Christine Khan ### 186007###Exhibitor Tutorial Organizer
2:00 PM - 2:45 PMGenedata Exhibitor Tutorial: Genedata Screener for HT-Flow: Analyzing Full Screens Across Plates in Minutes Christiane Eichbaum ### 184713###Exhibitor Tutorial Organizer @@@ Leigh Foster, PhD – Genedata ### 196526###Exhibitor Tutorial Presenter
2:00 PM - 2:45 PMInSphero Exhibitor Tutorial: Growth and Morphological Profiling of 3D Spheroids for High-throughput Cancer Drug Discovery with the Cell3iMager Randy Strube ### 188504###Exhibitor Tutorial Organizer @@@ Leena Mol Thuruthippallil – InSphero ### 194771###Exhibitor Tutorial Presenter
2:00 PM - 2:45 PMIonField Systems Exhibitor Tutorial: How Microplate Surface Properties and Chemicals May Affect Your Assays Paul Hensley – IonField Systems ### 43374###Exhibitor Tutorial Organizer @@@ Paul Hensley – IonField Systems ### 43374###Exhibitor Tutorial Presenter
2:00 PM - 2:45 PMMolecular Devices Exhibitor Tutorial: A New Approach for Oncology Research: Automating Multi-Parametric Screening of Cell Signal Pathways Across a Genome Caryn Tyler ### 188245###Exhibitor Tutorial Organizer @@@ Allan Sauvat – University Paris 6, Gustave Roussy ### 188002###Exhibitor Tutorial Presenter @@@ Oliver Kepp ### 196826###Exhibitor Tutorial Presenter
2:00 PM - 2:45 PMMultispan, Inc. Exhibitor Tutorial: Developing and Validating GPCR Cell Lines and Assays for Screening Jennifer Pham ### 194388###Exhibitor Tutorial Organizer @@@ Lisa Minor, PhD – In Vitro Strategies, LLC ### 43412###Exhibitor Tutorial Presenter
2:00 PM - 2:45 PMSiLA Consortium Exhibitor Tutorial: Data and Communication Standards in Lab Automation: From Concept to Tangible Realities Devon L. Johnston – SiLA Consortium ### 187456###Exhibitor Tutorial Organizer @@@ Thomas Frech – Xavo Systems AG ### 72734###Exhibitor Tutorial Presenter @@@ Alexander Brendel – infoteam Software AG ### 188051###Exhibitor Tutorial Presenter @@@ Niklaus Graber – SiLA Consortium ### 198576###Exhibitor Tutorial Presenter
2:00 PM - 2:45 PMUniversal Robots Exhibitor Tutorial: How Collaborative Robots Lower the Automation Barrier Craig Tomita ### 192260###Exhibitor Tutorial Organizer @@@ Scott Mabie – Universal Robots ### 198650###Exhibitor Tutorial Presenter
2:00 PM - 5:00 PMCareer Connections: Mentoring Sessions / One-on-One Career Counseling Sessions / Job Boards
2:30 PM - 3:00 PMBeverage Break in the Exhibit Hall
- 3:00 PM - 5:00 PMBiobanking: Evolving from Managing Small Molecules to Biological MoleculesSpecial Session
3:00 PM - 3:30 PMFrom Collection to Utilization: The Critical Role of Technology Innovation in Delivering Scientific Advances with Biological Samples Clive Green – AstraZeneca ### 184212###Speaker - Not Funded
3:30 PM - 4:00 PMLab Automation to Support a Biologics Repository: Lessons Learned Karen Billeci – Genentech ### 185705###Speaker - Not Funded
4:00 PM - 4:30 PMCreating an IPSC Biobank as a Service and for Developing Novel Therapeutics Marcie Glicksman – Orig3n, Inc Boston, MA, USA Creating an IPSC Biobank as a Service and for Developing Novel Therapeutics A great deal of phenotypic and genotypic diversity can be found among both disease and non- ### 62448###Speaker - Funded
4:30 PM - 5:00 PMThe Actelion Research Biobank: Experiences from Launching Biobanking Operations Within R&D of a Medium-sized Pharmaceutical Company Oliver Peter – Actelion Pharmaceuticals Ltd ### 185706###Speaker - Not Funded
- 3:00 PM - 5:00 PMCellular Biosensors and Genome Editing in Screening Assay DesignAssay Development & Screening
3:00 PM - 3:30 PMLessons Learned Using BRET2+ in High Throughput Screening Mary Ellen Digan, Ph.D. – Center for Proteomic Chemistry, Novartis Institutes for Biomedical Research, Inc ### 127360###Speaker - Funded
3:30 PM - 4:00 PMGenome Edited Gigaxonin-Knockout Cell Line Development and Primary Screening to Investigate Biological Mechanisms Underlying the Rare Disease Giant Axonal Neuropathy Melissa G. Mendez, PhD – Laboratory of Assay Development and Screening Technology (ADST), NCATS, NIH ### 142430###Speaker - Not Funded
4:00 PM - 4:30 PMA Luciferase-based Assay System to Monitor Protein-Protein Interactions in Live Cells Frederick J. King – The Genomics Institute of the Novartis Research Foundation ### 184291###Speaker - Not Funded
4:30 PM - 5:00 PMUltra-high Throughput Screen to Identify Chemical Probes of the Orphan Receptor GPR20 Using a Pharmacochaperone Strategy Layton H. Smith, PhD, MSCI – Sanford Burnham Prebys Medical Discovery Institute ### 184263###Speaker - Not Funded
- 3:00 PM - 5:00 PMData Visualization: Expert Data for Non-ExpertsInformatics
3:00 PM - 3:30 PMBioassay Variability and Reliability in the Published and Patent Literature John P. Overington – Stratified Medical ### 119536###Speaker - Funded
3:30 PM - 4:00 PMEnsuring Chemical Structure, Biological Data and Computational Model Quality Sean Ekins – Collaborative Drug Discovery ### 61292###Speaker - Funded
4:00 PM - 4:30 PMThe Needs for Chemistry Standards, Database Tools and Data Curation at the Chemical-biology Interface Antony J. Williams – Environmental Protection Agency, National Center of Computational Toxicology ### 184288###Speaker - Funded
4:30 PM - 5:00 PMPanel Discussion: Data Visualization: Expert Data for Non-Experts
- 3:00 PM - 5:00 PMHigh Content and High Throughput AutomationAutomation & High Throughput Technologies
3:00 PM - 3:30 PMCell-based Assay Development Through Design of Experiment and Automation Mitchell Hull – California Institute for Biomedical Research ### 184270###Speaker - Not Funded
3:30 PM - 4:00 PMA Flexible Workflow for Exploration and Prototyping of Analytical Solutions in High-Content Screening Oliver Leven – Genedata AG, Switzerland ### 184250###Speaker - Not Funded
4:00 PM - 4:30 PMAnalyzing Signal Transduction on a High Content Screening System Using Förster Resonance Energy Transfer Based Biosensors Alexander Schreiner – PerkinElmer Inc. ### 184244###Speaker - Not Funded
4:30 PM - 5:00 PMElastomeric Sensor Surfaces for High-throughput Phenotypic Screening of Cellular Force Generation Ivan Pushkarsky – University of California, Los Angeles ### 184275###Speaker - Tony B. Awardee
- 3:00 PM - 5:00 PMMicrophysiological SystemsMicro/Nano Technologies
3:00 PM - 3:30 PMCompact Mechanatronic System for the Perfusion, Control, Analysis, and Maintenance of Organ-on-chip Microbioreactors Dmitry A. Markov – Vanderbilt University ### 184266###Speaker - Tony B. Awardee
3:30 PM - 4:00 PMDevelopment of Microchip-Based Methods for Monitoring Reactive Nitrogen Species in Macrophage Cells Joseph M. Siegel – University of Kansas ### 184258###Speaker - Tony B. Awardee
4:00 PM - 4:30 PMGraphene-based Biocompatible Optoelectronic Platform for Light-controlled Activation of Cardiomyocytes Elena Molokanova, PhD – NTBS ### 184207###Speaker - Not Funded
4:30 PM - 5:00 PMA “Top-Down” Organ-on-a-Chip Approach for Metabolic Studies Based on Microfluidic Tissue-Slice Culture Sabeth Verpoorte – Groningen Research Institute of Pharmacy University of Groningen ### 62436###Speaker
- 3:00 PM - 5:00 PMMS & Other Label-Free Bioanalytics for ScreeningAdvances in Bioanalytics, Biomarkers and Diagnostics
3:00 PM - 3:30 PMHT-MALDI-MS as a Complete Label-free Drug Discovery Platform: From Target Characterization Through High-throughput Screening to Hit Follow Up
Scott A. Busby – Novartis Institutes for Biomedical Research ### 61350###Speaker - Not FundedThis Session Sponsored By:
3:30 PM - 4:00 PMThe Evolution of MALDI-TOF Mass Spectrometry Towards Ultra High Throughput Screening - 1536 Well Format and Beyond
Melanie Leveridge – GlaxoSmithKline, Stevenage UK ### 184211###Speaker - Not FundedThis Session Sponsored By:4:00 PM - 4:30 PMContinuing the Quest for a Mass Spectrometry-Based Plate Reader: Evaluating Laser Diode Thermal Desorption (LDTD) Coupled with Nanoliter Dispensing for HTS and HT-ADME Applications
Andrew D. Wagner – Bristol-Myers Squibb ### 43315###Speaker - Not FundedThis Session Sponsored By:4:30 PM - 5:00 PMDMPK Wave 1 Screening – an Integral Part of Early Drug Discovery at AstraZeneca
Erika Rehnström – AstraZeneca ### 184222###Speaker - Not FundedThis Session Sponsored By:
5:00 PM - 5:15 PMStudent Poster Award Winner Announcement
5:00 PM - 5:30 PMThe Lab Man Podcast - Student Poster Competition Winners
5:30 PM - 6:30 PMReception in Exhibit Hall Celebrating the 2016 SLAS Journal Achievement Award Honorees
5:30 PM - 6:30 PMStudent and Early Career Professionals Mixer
6:30 PM - 8:30 PMLate Night with LRIG - Rapid-Fire Innovation Session
7:15 AM - 9:00 AMAnalytical, Life Science and Diagnostic Association Special Session (ALDA) (Invitation Only)
7:45 AM - 8:00 AMMorning Beverage Break
7:30 AM - 8:30 AMTransitions – After the training ends...taking steps for a fulfilling career in science; Joanne Kamens, Ph.D. Executive Director, Addgene
7:30 AM - 6:00 PMRegistration Open
- 8:00 AM - 9:15 AMSpecial Interest Group (SIG)Special Interest Group (SIG)
8:00 AM - 9:15 AMHCS/HCA Data and Informatics Special Interest Group (SIG) Paul A. Johnston, PhD – Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh ### 62456###SIG Speaker - Not Funded @@@ Anne Carpenter – Broad Institute ### 43343###SIG Speaker - Not Funded @@@ Bartek Rajwa, PhD – Purdue University ### 184278###SIG Speaker - Not Funded
8:00 AM - 9:15 AMSample Management Special Interest Group (SIG)
8:00 AM - 9:15 AMScreen Design and Assay Technology Special Interest Group (SIG)
8:00 AM - 9:15 AMStem Cells and 3D Microtissues Special Interest Group (SIG)
Sponsored By:
8:00 AM - 9:15 AMTechnology Transfer and CRO/CMO Project Management Special Interest Group (SIG)
8:00 AM - 5:00 PMSpeaker Ready Room Open
- 9:30 AM - 10:15 AMExhibitor TutorialExhibitor Tutorial
9:30 AM - 10:15 AMFormulatrix, Inc. Exhibitor Tutorial: Automation and Miniaturization of AlphaLISA and AlphaPlex Assays Using Microfluidic Dispensing Technologies Jeremy Lambert – Formulatrix, Inc. ### 194214###Exhibitor Tutorial Organizer @@@ Jeremy Lambert – Formulatrix, Inc. ### 194214###Exhibitor Tutorial Presenter @@@ Lindsay Nelson ### 198923###Exhibitor Tutorial Presenter @@@ Gene E. Ananiev – UW Madison ### 198924###Exhibitor Tutorial Presenter
9:30 AM - 10:15 AMGenedata Exhibitor Tutorial: Genedata Screener for SPR: Full Integration of SPR into the Screening Analysis Workflow Christiane Eichbaum ### 184713###Exhibitor Tutorial Organizer @@@ Stephan Steigele – Genedata AG ### 196528###Exhibitor Tutorial Presenter
9:30 AM - 10:15 AMHorizon Exhibitor Tutorial: Target ID & Validation via CRISPR-Cas9 Jon Moore – Horizon Discovery ### 188233###Exhibitor Tutorial Organizer @@@ Jon Moore – Horizon Discovery ### 188233###Exhibitor Tutorial Presenter
9:30 AM - 10:15 AMLumigen, A Beckman Coulter Company Exhibitor Tutorial: Using SPARCL Technology and BMG LABTECH Microplate Readers to Develop Immunoassays for Biomarker Detection and Pharmacokinetic Studies Kristen Pauly ### 190682###Exhibitor Tutorial Organizer @@@ Mark J. Cameron – Beckman Coulter ### 125027###Exhibitor Tutorial Presenter
9:30 AM - 10:15 AMPerkinElmer Exhibitor Tutorial: How to Validate and Automate Phenotypic Screening and Profiling Across Multiple Cell Lines Pam Clemens ### 186764###Exhibitor Tutorial Organizer
9:30 AM - 10:15 AMPerkinElmer Exhibitor Tutorial: How to Validate and Automate Phenotypic Screening and Profiling Across Multiple Cell Lines Marisol Calvo ### 196647###Exhibitor Tutorial Organizer @@@ Seungtaek Lee – PerkinElmer ### 198620###Exhibitor Tutorial Presenter @@@ Michelle M. Walk, BS, MA – PerkinElmer ### 198621###Exhibitor Tutorial Presenter
9:30 AM - 10:15 AMThe Transcriptic Robotic Cloud Laboratory: The Future of Science Taylor Murphy ### 194970###Exhibitor Tutorial Organizer @@@ Conny Scheitz – Transcriptic ### 198658###Exhibitor Tutorial Presenter
9:30 AM - 10:15 AMThermo Fisher Scientific Exhibitor Tutorial: How Innovative Microplate Reader Features Can Improve Your Luminometric Assay Performance Christa Lamps ### 188845###Exhibitor Tutorial Organizer @@@ Marika Rialto ### 194308###Exhibitor Tutorial Presenter
9:30 AM - 11:30 AMSLAS2017 Exhibitor Space Draw
9:30 AM - 6:00 PMExhibition Open
9:30 AM - 6:00 PMPosters on Display in Exhibition
9:30 AM - 6:00 PMSLAS Member Center
9:45 AM - 10:15 AMThe Lab Man Podcast - JBS Guest Editor Jonathan Wingfield. JBS Special Issue on Advances in Mass Spectrometry within Drug Discovery
10:00 AM - 10:30 AMBeverage Break in the Exhibit Hall
- 10:30 AM - 12:30 PMAdvances in Biomarkers Discovery: Sample Preparation, Analysis and Data ProcessingAdvances in Bioanalytics, Biomarkers and Diagnostics
10:30 AM - 11:00 AMUrine Proteomics: From New Developments to New Insights Hanno Steen – Harvard Medical School and Boston Children's Hospital ### 184301###Speaker - Funded
11:00 AM - 11:30 AMImaging Mass Spectrometry Applied to Biomarker Discovery Richard A. Yost, PhD – University of Florida ### 184280###Speaker - Funded
11:30 AM - 12:00 PMBiomarker ELISA Assays to the Clinic: Same Old Gold Standard Steven P. Piccoli – Bristol-Myers Squibb ### 184287###Speaker - Not Funded
12:00 PM - 12:30 PMDecoding a Complex Sample Extraction Process for Biotherapeutics Mass Spectrometry Analysis Ian Moore – SCIEX ### 184232###Speaker - Not Funded
- 10:30 AM - 12:30 PMApplication of CRISPR and RNAi in Genetic Screens for Target Discovery and ValidationCellular Technologies
10:30 AM - 11:00 AMGenetic Screens with CRISPR-Cas9 Technology: A New Hope in Functional Genomics John G. Doench – Broad Institute of MIT and Harvard ### 184220###Session Chair & Speaker - WITH Funding
11:00 AM - 11:30 AMNo Magic Bullets: Functional Genomics Panel Discussion John G. Doench – Broad Institute of MIT and Harvard ### 184220###Speaker @@@ Samuel A. Hasson, PhD – Pfizer Neuroscience ### 185944###Speaker @@@ Robert Damoiseaux ### 185940###Speaker @@@ Ralph J. Garippa, Ph.D – Memorial Sloan-Kettering Cancer Center ### 184254###Speaker @@@ John N. Feder – Bristol-Myers Squibb ### 184300###Speaker
11:30 AM - 12:00 PMGenetic Screens as Target Fishing Tournaments: Landing the Big One--Hook, Line and Sinker Ralph J. Garippa, Ph.D – Memorial Sloan-Kettering Cancer Center ### 184254###Speaker - Not Funded
12:00 PM - 12:30 PMA Pooled FACS Based Genome Scale RNAi and CRISPR Hit Follow up Loss of Function Screen Identifies Genes Involved in Maintaining HIV Latency in a Jurkat Cell Model of HIV Reactivation John N. Feder – Bristol-Myers Squibb ### 184300###Speaker - Funded
- 10:30 AM - 12:30 PMCommericialization Perspectives for Micro and Nanofluidic DevicesMicro/Nano Technologies
10:30 AM - 11:00 AMA New Integrated Platform for High Quality and Low Cost Gene Expression Analysis Kristina Lind, PhD in Molecular Biotechnology – TATAA Biocenter ### 184262###Speaker
11:00 AM - 11:30 AMAdvanced Genomic Analyses Using Massively Parallel Molecular Barcoding Rajiv Bharadwaj – 10X Genomics ### 119606###Speaker - Funded
11:30 AM - 12:00 PMOvercoming Matrix Effects from Disease Populations Using Microfluidic Technology: Implementation in Phase III Clinical Study Kathi J. Williams – Genentech, Inc. ### 184290###Speaker - Not Funded
12:00 PM - 12:30 PMA Powerful New Pin Tool Method for Precisely Delivering Nanoliter Samples to Dry Microplates John Herich, BS – V&P SCIENTIFIC ### 184227###Speaker - Not Funded
- 10:30 AM - 12:30 PMData WranglingInformatics
10:30 AM - 11:00 AMAddressing Today’s Scientific Data Challenges Through Workflow Tools Matt Hahn ### 185793###Session Chair & Speaker - No Funding
11:00 AM - 11:30 AMTackling Analytical Knowledge Transfer Obstacles in Externalized Environments Graham A. McGibbon, PhD – ACD/Labs ### 78009###SIG Speaker - Not Funded
11:30 AM - 12:00 PMTowards Automated Interpretation of LC-MS Data for Quality Assurance of a Screening Collection Daniel H. Addison – AstraZeneca ### 184209###Speaker - Not Funded
12:00 PM - 12:30 PMSurface Pattern Classification as a Novel Mode of Inhibition (MOI) Characterization for Inhibitors from High Throughput Screening Ji-Hu Zhang – Novartis ### 184223###Speaker - Not Funded
- 10:30 AM - 12:30 PMEmerging Techniques for Clinical Laboratory AutomationAutomation & High Throughput Technologies
10:30 AM - 11:00 AMMALDI-TOF MS as a High Throughput Identification System for Clinical Microbiology Omai Garner – UCLA Department of Pathology and Laboratory Medicine ### 184248###Session Chair & Speaker - No Funding
11:00 AM - 11:30 AMUsable Nucleic Acids from Problematic Sources Tetsuya Ueda – Research and Development Division, Precision System Science ### 45080###Speaker - Not Funded
11:30 AM - 12:00 PMMass Spectrometry in the Clinical Laboratory David Herold, MD ### 203506###Speaker
12:00 PM - 12:30 PMMulti-scale Integrated Lab-on-a-Chips: From Bioanalysis to Clinical Diagnostics Yong Zeng – University of Kansas ### 184256###Speaker - Not Funded
- 10:30 AM - 12:30 PMPhenotypic, Model Organism and High Content Screening AssaysAssay Development & Screening
10:30 AM - 11:00 AMHigh Content Screening Is Made Alive Florian Fuchs – Novartis Pharma AG ### 184302###Session Chair & Speaker - WITH Funding
11:00 AM - 11:30 AMUsing Human Astrocyte-based Disease Models for Drug Discovery Targeting Neurological Diseases Wei Zheng – NCATS/NIH ### 184234###Speaker - Not Funded
11:30 AM - 12:00 PMEnabling 3D Cell-based Spheroid HTS Assays in 384 and 1,536-well Plate Formats Franck G. Madoux, PhD – The Scripps Research Institute ### 184215###Speaker - Not Funded
12:00 PM - 12:30 PMA Powerful New High-Throughput Zebrafish Behavioral Chemical Screen to Rapidly Identify and Optimize Novel Neurotherapeutic Drug Candidates in a Target-Agnostic Manner Andrew J. Rennekamp – Massachusetts General Hospital, Harvard Medical School, and The Broad Institute ### 184241###Speaker - Tony B. Awardee
9:30 AM - 12:30 PMCareer Connections: Mentoring Sessions / One-on-One Career Counseling Sessions / Job Boards
- 12:30 PM - 1:15 PMExhibitor TutorialExhibitor Tutorial
12:30 PM - 1:15 PMArtel Exhibitor Tutorial: Standardization of Tecan® Freedom EVO® liquid handling platforms using the QC Kit Kerry Fairlie ### 193536###Exhibitor Tutorial Organizer @@@ George W. Rodrigues, PhD – Artel ### 134481###Exhibitor Tutorial Presenter @@@ Keith J. Albert, PhD – Artel ### 43320###Exhibitor Tutorial Presenter @@@ Joseph T. Sullivan – Tecan ### 199873###Exhibitor Tutorial Presenter
12:30 PM - 1:15 PMBiodesy Exhibitor Tutorial: Real-Time, Solution-Based Measurement of Protein Conformational Change – Use Cases in Drug Discovery Josh Salafsky, PhD – Biodesy ### 185807###Exhibitor Tutorial Organizer @@@ Elizabeth Donohue Vo, PhD – University of California San Francisco ### 188269###Exhibitor Tutorial Presenter @@@ Jennifer A. Piesvaux, BS/MS – Merck ### 201222###Exhibitor Tutorial Presenter
12:30 PM - 1:15 PMFesto Exhibitor Tutorial: How Industrial Automation Solutions Improve Processes in the Lab and the Decision of Make vs Buy Andrew Wagner – Festo Corporation ### 187271###Exhibitor Tutorial Organizer @@@ Tom Geiger ### 194223###Exhibitor Tutorial Presenter @@@ Marcus Wills ### 194727###Exhibitor Tutorial Presenter @@@ William Hathaway ### 194728###Exhibitor Tutorial Presenter
12:30 PM - 1:15 PMHamilton Exhibitor Tutorial: Mastering Automation in Your Laboratory - Highlights for NGS and Mass Spectrometry Sample Preparation Kelli Cavallaro ### 190842###Exhibitor Tutorial Organizer @@@ J. Russ Carmical, PhD – Diversigen ### 196648###Exhibitor Tutorial Presenter @@@ L.T. Cornmesser – Joint Genome Institute ### 196649###Exhibitor Tutorial Presenter
12:30 PM - 1:15 PMPerkinElmer Exhibitor Tutorial: Evaluation of AlphaPlex for Pro-inflammatory Cytokine Measurement and Development of Epigenetics Assays Using AlphaLISA Pam Clemens ### 186764###Exhibitor Tutorial Organizer
12:30 PM - 1:15 PMTTP Labtech Exhibitor Tutorial: Low-Cost Single-Cell Transcriptome Sequencing Using Automated, High-Throughput and Low-Sample Input Workflows Dawn Browning ### 184722###Exhibitor Tutorial Organizer @@@ Louise Laurent – University of Callifornia San Diego ### 195181###Exhibitor Tutorial Presenter
12:30 PM - 1:30 PMLunch in the Exhibition Hall
- 12:30 PM - 1:45 PMExhibitor TutorialExhibitor Tutorial
12:30 PM - 1:45 PMBrooks Automation Exhibitor Tutorial: Expanding to a Large Molecule Storage Strategy: Cold Chain Management as a Key to Discovery and Reproducibility Sue Jones ### 198664###Exhibitor Tutorial Organizer @@@ David Lewandowski ### 184712###Exhibitor Tutorial Presenter
12:30 PM - 1:45 PMMolecular Sensing Exhibitor Tutorial: Interrogating Ligand:Target Interactions using Back-Scattering Interferometry Yields Mechanistic Insights and Aids in Compound Prioritization Julian Abery ### 186762###Exhibitor Tutorial Organizer @@@ Layton H. Smith, PhD, MSCI – Sanford Burnham Prebys Medical Discovery Institute ### 184263###Exhibitor Tutorial Presenter @@@ Scot Weinberger – Molecular Sensing, Inc. ### 61279###Exhibitor Tutorial Presenter
12:30 PM - 1:45 PMLabcyte Inc. Exhibitor Tutorial: Nano-Dispensing Technology Assessment for Next-Gen Lab Automaton and Screening Valerie Weld – Labcyte Inc. ### 184716###Exhibitor Tutorial Organizer @@@ Rebecca Lee-Lu – Dow AgroSciences ### 193068###Exhibitor Tutorial Presenter
12:30 PM - 1:45 PMPerkinElmer Exhibitor Tutorial: Development of Global Biobank Standards Through Validated Technology Pipelines: Integrating Sample Collection, Nucleic Acid Processing and Quality Control for Precision Medicine Initiatives Sheryl Duffy ### 184717###Exhibitor Tutorial Organizer @@@ Andrew Brooks – RUCDR ### 198642###Exhibitor Tutorial Presenter
12:30 PM - 1:45 PMPromega Corporation Exhibitor Tutorial: Applications of Real-Time Assays for Translational Research Linda Link ### 184719###Exhibitor Tutorial Organizer @@@ Terry L. Riss, PhD – Promega Corporation ### 62431###Exhibitor Tutorial Presenter @@@ G. Sitta Sittampalam, PhD – NIH/NCATS ### 119623###Exhibitor Tutorial Presenter @@@ Ralph J. Garippa, Ph.D – Memorial Sloan-Kettering Cancer Center ### 184254###Exhibitor Tutorial Presenter
- 12:30 PM - 2:30 PMExhibitor TutorialExhibitor Tutorial
12:30 PM - 2:30 PMAgilent Exhibitor Tutorial: An Automated Platform for Target Capture-Based NGS Cancer Panel Brittany Ogden ### 191777###Exhibitor Tutorial Organizer
12:30 PM - 2:30 PMBeckman Coulter Life Sciences Exhibitor Tutorial: Accelerate Discovery with Automated NGS Sample Prep Donna Gorman ### 184709###Exhibitor Tutorial Organizer @@@ Zach Smith, M.S. – Beckman Coulter Life Sciences ### 142428###Exhibitor Tutorial Presenter @@@ Alisa Jackson – Beckman Coulter Life Sciences ### 199907###Exhibitor Tutorial Presenter @@@ Norm Allaire – Biogen ### 199908###Exhibitor Tutorial Presenter @@@ David Horvath – Beckman Coulter Life Sciences ### 199909###Exhibitor Tutorial Presenter
1:00 PM - 1:30 PMJALA/JBS VIP Meet & Greet: Meet JBS Editor-in-Chief Robert M. Campbell, PhD (Eli Lilly and Company)
1:00 PM - 2:00 PMMentoring - Enriching your mentoring relationships from both sides; Joanne Kamens, Ph.D. Executive Director, Addgene
1:00 PM - 3:00 PMPoster Presentations (Even Numbered Posters)
1:30 PM - 2:00 PMJALA/JBS VIP Meet & Greet: "Mass Spectrometry within Drug Discovery" with JBS Special Issue Guest Editor Jonathan Wingfield of AstraZeneca
2:00 PM - 2:30 PMJALA/JBS VIP Meet & Greet: "Assembly and Transformation of a Synthetic Yeast Artificial Chromosome with a Multigene Cassette that Enhances Xylose Utilization into Saccharomyces Cerevisiae" with JALA Author Steve Riedmuller of Hudson Control Group
- 2:00 PM - 2:45 PMExhibitor TutorialExhibitor Tutorial
2:00 PM - 2:45 PMAxol Bioscience Tutorial, presented by Dr. Alfredo Cabrera from Janssen Pharmaceutica (Johnson & Johnson) - Modelling Alzheimer’s Disease: A High Throughput-Compatible Assay for Detecting TAU Aggregation Using iPSC-Derived Cortical Neurons António Gouveia ### 187455###Exhibitor Tutorial Organizer @@@ Alfredo Cabrera – Janssen Pharmaceutica (Johnson & Johnson ) ### 196395###Exhibitor Tutorial Presenter
2:00 PM - 2:45 PMBMG LABTECH Exhibitor Tutorial: Interrogation of Modulators of Small GTPase Activity: Screening GAPs and GEFs with the PHERAstar® FSX from BMG LABTECH and Transcreener ® GDP Assays from BellBrook Labs Carl Peters – BMG LABTECH ### 45027###Exhibitor Tutorial Organizer
2:00 PM - 2:45 PMClontech Laboratories, Inc. Exhibitor Tutorial: Advances in Pluripotent Stem Cell Culturing and Differentiation: Applications for Generation of Hepatocytes and Pancreatic Beta Cells from Definitive Endoderm Chris Wang ### 192736###Exhibitor Tutorial Organizer @@@ Catharina Ellerström, DDS, PhD – Takara Bio Europe AB ### 194782###Exhibitor Tutorial Presenter
2:00 PM - 2:45 PMHelix Linear Technologies, Inc.: Using Lead Screws and Linear Actuators in Medical Devices and Laboatory Equipment Christopher M. Nook – Helix Linear Technologies ### 192302###Exhibitor Tutorial Organizer @@@ Christopher M. Nook – Helix Linear Technologies ### 192302###Exhibitor Tutorial Presenter
2:00 PM - 2:45 PMIcagen, Inc. Exhibitor Tutorial: Overcoming Challenges of Developing Sodium Channels and SLC Transporters as Drug Discovery Targets Krista Steger ### 185798###Exhibitor Tutorial Organizer @@@ Brett Antonio – Icagen Inc ### 188263###Exhibitor Tutorial Presenter @@@ Nathan Zahler – Icagen, Inc ### 196573###Exhibitor Tutorial Presenter
2:00 PM - 2:45 PMInSphero and PerkinElmer Exhibitor Tutorial: Advances in Drug Testing Using Scaffold Free 3D Cell Culture in Automated High Content Screening Systems Randy Strube ### 188504###Exhibitor Tutorial Organizer @@@ Dina Sirypangno ### 200687###Exhibitor Tutorial Presenter @@@ Jacob G. Tesdorpf – PerkinElmer ### 200688###Exhibitor Tutorial Presenter
2:00 PM - 2:45 PMLabcyte Inc. Exhibitor Tutorial: Interrogating the PI3K Pathway using the Labcyte Echo® Series of Acoustic Liquid Handlers Valerie Weld – Labcyte Inc. ### 184716###Exhibitor Tutorial Organizer @@@ John Lesnick – Labcyte Inc ### 125074###Exhibitor Tutorial Presenter @@@ Linda Orren – Labcyte ### 142588###Exhibitor Tutorial Presenter
2:00 PM - 2:45 PMMolecular Devices Exhibitor Tutorial: Multidimensional High-Throughput Screening with the New ImageXpress Micro Confocal System Caryn Tyler ### 188245###Exhibitor Tutorial Organizer @@@ Grischa Chandy ### 196827###Exhibitor Tutorial Presenter
2:00 PM - 2:45 PMNexcelom Bioscience Exhibitor Tutorial: Rapid 3D Tumor Spheroid in Vitro Assays for Drug Screening Using the Celigo Imaging Cytometer Sara Barker ### 190834###Exhibitor Tutorial Organizer @@@ Paul Weingarten – NantBioscience ### 194446###Exhibitor Tutorial Presenter @@@ Olivier Dery, PhD – Nexcelom Bioscience ### 194447###Exhibitor Tutorial Presenter
2:00 PM - 2:45 PMBiosero Exhibitor Tutorial: Robust Implementation of Automation Workcells Using New and Used Equipment Kristen Macias ### 188232###Exhibitor Tutorial Organizer @@@ David Dambman – Biosero, Inc ### 119589###Exhibitor Tutorial Presenter
2:00 PM - 2:45 PMTitian Software Exhibitor Tutorial: Managing Complex Biologic Workflows Efficiently - A Case Study at Genentech Angela Cunniff ### 188225###Exhibitor Tutorial Organizer @@@ Karen Billeci – Genentech ### 185705###Exhibitor Tutorial Presenter @@@ Edmund Wilson ### 194999###Exhibitor Tutorial Presenter
2:00 PM - 5:00 PMCareer Connections: Mentoring Sessions / One-on-One Career Counseling Sessions / Job Boards
3:00 PM - 3:30 PMThe Lab Man Podcast - JALA Guest Editor Joe Olechno, JALA Special Issue on Advancing Scientific Innovation with Acoustic Droplet Ejection
2:30 PM - 3:00 PMBeverage Break in the Exhibition Hall
- 3:00 PM - 5:00 PMCollaboration: Drug Discovery in the Internet EraInformatics
3:00 PM - 3:30 PMCDD Vault: Co-Evolving Collaborative Drug Discovery 3 Ways Barry Bunin, PhD – Collaborative Drug Discovery (CDD) ### 119488###Session Chair & Speaker - WITH Funding
3:30 PM - 4:00 PMThe PubChem BioAssay Data Warehouse: A Showcase of Big Data Management Yanli Wang – National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health ### 184204###Speaker - Not Funded
4:00 PM - 4:30 PMOutsourcing Routine Drug Discovery - Theory into Practice. UCBs Informatics Experience of Supporting Outsourced Discovery David Lee – UCB ### 184264###Speaker - Not Funded
4:30 PM - 5:00 PMRole of Compound Management in an Environment of Increasing (Contractual & Regulatory) Complexity Inge Moelans – Janssen Research & Development ### 184255###Speaker - Not Funded
- 3:00 PM - 5:00 PMCompound Libraries and Medicinal Chemistry in ScreeningAssay Development & Screening
3:00 PM - 3:30 PMHistone Acetyltransferase Inhibitors, from Screening to Optimization - A Tricky Track Jonathan Baell – Monash Institute of Pharmaceutical Sciences ### 61305###Session Chair & Speaker - WITH Funding
3:30 PM - 4:00 PMHigh Throughput Screening of Metagenomic DNA Libraries Louis Cohen – Icahn School of Medicine at Mount Sinai ### 184208###Speaker - Funded
4:00 PM - 4:30 PMKey Considerations in Compound Collection Composition and Quality – Seeding Success in Hit Follow Up Kristian Birchall – MRC Technology ### 184231###Speaker - Not Funded
4:30 PM - 5:00 PMEfficient Drug Discovery Using High Fidelity DNA-encoded Small-molecule Library Technologies Allan Beck Christensen, Ph.D – Vipergen APS ### 72765###Speaker - Not Funded
- 3:00 PM - 5:00 PMDiagnostics and Point-of-Care MicrodevicesMicro/Nano Technologies
3:00 PM - 3:30 PMElectrokinetic Micro- and Nanofluidic Technologies for Quantitative Detection of Viral Nucleic Acids Sumita Pennathur – UCSB ### 61282###Speaker - Funded
3:30 PM - 4:00 PMIntegrated Microfluidic Electroporator for Multimolecular Delivery into Purified Target Cells Soojung C. Hur – Vortex Biosciences, Inc ### 184224###Speaker - Not Funded
4:00 PM - 4:30 PMMicrofluidically-fabricated Flowable Microporous Hydrogel Scaffolds for 3D Tissue Culture Jaekyung Koh – Bioengineering, UCLA ### 184213###Speaker - Not Funded
4:30 PM - 5:00 PMUltrasensitive Detection of Serum Biomarkers Using Surface Plasmon Resonance Imaging (SPRi) Marinella Sandros, PhD – HORIBA Scientific ### 184238###Speaker - Not Funded
- 3:00 PM - 5:00 PMExtreme AutomationAutomation & High Throughput Technologies
3:00 PM - 3:30 PMHigh Throughput Discovery of Solar Fuels Materials for Operation Outdoors in Corrosive Electrolyte John Gregoire – California Institute of Technology ### 184205###Speaker - Funded
3:30 PM - 4:00 PMThe Application of Automated Frozen Aliquotting Technology to the Bioanalysis of Labile Compounds Glenn A. Smith – CryoXtract Instruments ### 184217###Speaker - Not Funded
4:00 PM - 4:30 PMA Microfluidic Platform for 3-D Cell-based Screening of Cancer Treatments Under Chronic and Transient Hypoxia Samantha M. Grist – The University of British Columbia ### 123195###Speaker - Tony B. Awardee
4:30 PM - 5:00 PMExtreme Automation: From Hypoxic Chambers to the World’s Oceans and 3 Billion Poor People in the Developing World Brian Rasnow, Ph.D. – Etaluma Inc & CSUCI ### 184274###Session Chair & Speaker - WITH Funding
- 3:00 PM - 5:00 PMGene Editing for Disease ModelsCellular Technologies
3:00 PM - 3:30 PMGenome Engineering with Zinc Finger Nucleases Edward Rebar – Sangamo BioSciences ### 184268###Session Chair & Speaker - No Funding
3:30 PM - 4:00 PMModeling Human Cancer in the Mouse via Somatic Genome Editing Andrea Ventura – MSKCC ### 184285###Speaker - Funded
4:00 PM - 4:30 PMCRISPR/Cas9 Technology in Target Discovery, Hit Finding and Translational Studies Lorenz M. Mayr – AstraZeneca ### 61296###Speaker - Not Funded
4:30 PM - 5:00 PMCRISPR-Cas9 KO Screening Identifies Pathway Regulators in Glucose Starvation Jonathan Moore – Horizon Discovery Ltd. ### 184221###Speaker - Not Funded
- 3:00 PM - 5:00 PMPhysiologically Relevant Target StrategiesDrug Target Strategies
3:00 PM - 3:30 PMHigh-throughput Drug Discovery in Zebrafish Models for Dravet Syndrome Scott C. Baraban – University of California, San Francisco (UCSF) ### 184259###Speaker - Funded
3:30 PM - 4:00 PMQuantifying Biased Ligands for G Protein-Coupled Receptors Fred Ehlert ### 195105###Speaker - Funded
4:00 PM - 4:30 PMPhenotypic Primary Cell Screening and Tissue-specific Chemical Proteomics Identifies a Novel Small Molecule That Enhances Photoreceptor Differentiation and Survival John A. Fuller, Ph.D. – Johns Hopkins University School of Medicine ### 142427###Speaker - Not Funded
4:30 PM - 5:00 PMConformational Screening for Hard and Soft Targets Joshua Salafsky – Biodesy, Inc. ### 184203###Speaker - Not Funded
5:00 PM - 6:00 PMReception in Exhibition Hall
6:30 PM - 9:30 PMTuesday Night Celebration – USS MidwaySponsored by Hamilton
Sponsored By Hamilton Company: Hamilton Company7:45 AM - 8:00 AMMorning Beverage Break
8:00 AM - 9:15 AMJALA & JBS Author Workshop: How to Get Your Work Published
- 8:00 AM - 9:15 AMSpecial Interest Group (SIG)Special Interest Group (SIG)
8:00 AM - 9:15 AMAcademic Drug Discovery Special Interest Group (SIG) Michelle R. Arkin, PhD – Department of Pharmaceutical Chemistry, School of Pharmacy, University of California, San Francisco ### 61294###SIG Speaker - Not Funded @@@ Thomas Lundbäck – Chemical Biology Consortium Sweden, Science for Life Laboratories, Karolinska Institutet ### 78046###SIG Speaker - Not Funded @@@ Catherine Kettleborough ### 193952###SIG Speaker - Not Funded @@@ Stefan Vasile, PhD – Sanford Burnham Prebys Medical Discovery Instute ### 193953###SIG Speaker - Not Funded
8:00 AM - 9:15 AMAutomation Quality Control Special Interest Group (SIG) John T. Bradshaw, PhD – Artel ### 184708###SIG Speaker - Not Funded @@@ George W. Rodrigues, PhD – Artel ### 134481###SIG Speaker - Not Funded
8:00 AM - 9:15 AMCompound Combination Special Interest Group (SIG) Oliver Leven – Genedata AG, Switzerland ### 184250###SIG Speaker - Not Funded @@@ Stephen Steigele ### 192345###SIG Speaker - Not Funded
8:00 AM - 9:15 AMDrug Repurposing Special Interest Group (SIG)
8:00 AM - 9:15 AMInformatics Special Interest Group (SIG)
8:00 AM - 9:15 AMLabware Leachables Special Interest Group (SIG)
8:00 AM - 9:15 AMWomen Professionals in Science and Technology Special Interest Group (SIG)
8:00 AM - 12:00 PMSpeaker Ready Room Open
8:00 AM - 1:30 PMRegistration Open
8:00 AM - 5:30 PMBag Check
9:00 AM - 9:30 AMBeverage Break in Exhibit Hall
9:00 AM - 11:45 AMCareer Connections: Mentoring Sessions / One-on-One Career Counseling Sessions / Job Boards
9:00 AM - 1:00 PMExhibition Open
9:00 AM - 1:00 PMSLAS Member Center
9:15 AM - 9:30 AMNew Product Award Announcement
- 9:30 AM - 11:30 AMAssay Platforms for BiologicsAssay Development & Screening
9:30 AM - 10:00 AMHigh-Throughput Screening of Monoclonal Antibodies to Multiplexed Antigens Ben Hoffstrom – Fred Hutch Cancer Research Center ### 184294###Speaker - Funded
10:00 AM - 10:30 AMScreening and Characterisation Assays to Overcome Challenges in Biologics Discovery Elizabeth H. England – Antibody Discovery and Protein Engineering, MedImmune, UK ### 184214###Speaker - Not Funded
10:30 AM - 11:00 AMAutocrine-based Selection from Antibody Libraries Reveals New Pathways to Pluripotency and Cancer Joel Blanchard – Scripps Research Institute ### 61342###Speaker - Not Funded
11:00 AM - 11:30 AMA Universal Pharmacokinetic Assay for Biologic IgG Drugs with Utility in Multiple Preclinical Species Using Spatial Proximity Analyte Reagent Capture Luminescence (SPARCL) Mark J. Cameron – Beckman Coulter ### 125027###Speaker - Not Funded
- 9:30 AM - 11:30 AMAutomating Novel Analytical Tools for PKA, Drug-Drug Combination and Synergy Assays, Drug RepurposingAutomation & High Throughput Technologies
9:30 AM - 10:00 AMA Rapid High-throughput 3D Tumor Spheroid Image Cytometry Screening Method for Drug Discovery Scott Cribbes ### 203893###Speaker
10:00 AM - 10:30 AMAutomated and High-throughput Studies of Drug Combinations Using Acoustic Liquid Handling in Multiple Biomedical Fields Giovanni Paternostro – Sanford Burnham Prebys Medical Discovery Institute ### 184299###Speaker - Not Funded
10:30 AM - 11:00 AMDevelopment of a Platform to Enable Fully Automated Cross-Titration Experiments Jason Cassaday – Merck ### 184202###Speaker - Not Funded
11:00 AM - 11:30 AMAn Automated Miniaturized Method to Perform and Analyze Antimicrobial Drug Synergy Assays Timothy P. Spicer – Scripps Florida ### 184233###Speaker - Funded
- 9:30 AM - 11:30 AMCrowdsourcing ScienceInformatics
9:30 AM - 10:00 AMCrowdfunding Personal Genomics KT Pickard – StartCodon ### 184279###Speaker - Not Funded
10:00 AM - 10:30 AMOrphan Disease Drug Discovery Using Model Organisms Ethan Perlstein – Perlstein Lab PBC ### 184283###Session Chair & Speaker - WITH Funding
10:30 AM - 11:00 AMCrowdsourced Lead Discovery: Accelerated Neglected Tropical Disease Medicinal Chemistry Using a Distributed Model Michael P. Pollastri – Northeastern University ### 184239###Speaker - Funded
11:00 AM - 11:30 AMThe Repurposing Hub: A Next-generation Clinical Drug Library and Web Resource for Crowdsourced Drug Discovery Steven M. Corsello, MD – Broad Institute ### 184277###Speaker - Tony B. Awardee
- 9:30 AM - 11:30 AMPhenotypic and Systems-Based Strategies for Novel Drug TargetsDrug Target Strategies
9:30 AM - 10:00 AMFratricidin: An Agonist Antibody That Induces Human Malignant Cells to Kill One Another Richard A. Lerner – The Scripps Research Institute ### 184293###Speaker - Not Funded
10:00 AM - 10:30 AMNew Tools for the Study of Lysine Methylation Signaling in Epigenetic and Disease Regulation Or Gozani, M.D., Ph.D. – Stanford University ### 184237###Speaker - Funded
10:30 AM - 11:00 AMThree Dimensional Spatial Mapping of Human Explant Lungs Associated with Cystic Fibrosis Neha Garg – Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego ### 184292###Speaker - Not Funded
11:00 AM - 11:30 AMPhenotypic Screening with Ras-FRET Biosensors Identifies Cancer Stem Cell Inhibitors Daniel Abankwa – Turku Centre for Biotechnology, Åbo Akademi University ### 184218###Speaker - Not Funded
- 9:30 AM - 11:30 AMScaling Challenging Cell Models for High-Quality High Throughput ScreenCellular Technologies
9:30 AM - 10:00 AMIntegrating Bioengineering and Optical Imaging Approaches for Quantitative Assessment of Treatment Response in 3D Tumor Models Imran Rizvi, PhD – Brigham and Women's Hospital and Massachusetts General Hospital, Harvard Medical School ### 184251###Speaker - Funded
10:00 AM - 10:30 AMToward Minimally Invasive Readouts for Unlocking the Potential of Complex Cell Models in Lead Discovery Christophe Antczak – Novartis Institutes for Biomedical Research ### 184219###Speaker - Funded
10:30 AM - 11:00 AMNext Generation Assays for Next Generation Oncology Targets Serena Silver – Novartis Institutes for BioMedical Research ### 142437###Speaker - Not Funded
11:00 AM - 11:30 AMFlow Cytometry Enables Multiplexed Measurements of Genetically-encoded Sensors Based on Intramolecular Förster Resonance Energy Transfer Adam Zweifach, Ph.D. – Department of Molecular and Cell Biology, University of Connecticut ### 61263###Speaker - Not Funded
- 9:30 AM - 11:30 AMSingle Cell AnalysesMicro/Nano Technologies
9:30 AM - 10:00 AMPlasmonics-enabled Single-molecule and Temperature Detection Somin Eunice Lee – University of Michigan, Department of Electrical Engineering & Computer Science ### 119551###Speaker - Funded
10:00 AM - 10:30 AMA Frequency-multiplexed Parallel Flow Cytometer for High-throughput Screening and Drug Discovery Jonathan Lin – UCLA ### 184269###Speaker - Not Funded
10:30 AM - 11:00 AMDroplet-Microarray Sandwiching Chip as Miniaturized Pipetting Free Platform for High Throughput Screenings of Live Cells Based on Superhydrophilic-superhydrophobic Surface Patterning Anna A. Popova – Institute of Toxicology and Genetics (ITG) , Karlsruhe Institute of Technology ### 184210###Speaker - Tony B. Awardee
11:00 AM - 11:30 AMLeveraging the IncuCyte Technology for High-Throughput Chemotaxis Assays Jing Chen – BMS ### 184235###Speaker - Not Funded
10:00 AM - 11:00 AMThe Lab Man Podcast - New Product Award Winners
11:30 AM - 12:00 PMLunch in the Exhibition Hall
11:45 AM - 12:00 PMPassport to Prizes Award Announcements
- 12:00 PM - 1:15 PMSpecial Interest Group (SIG)Special Interest Group (SIG)
12:00 PM - 1:15 PMADMET Special Interest Group (SIG) David Stresser ### 194395###SIG Speaker - Not Funded @@@ Robert Dunn ### 194396###SIG Speaker - Not Funded
12:00 PM - 1:15 PMAutomated Sample Preparation of Pharmaceutical Dosage Forms Special Interest Group (SIG)
12:00 PM - 1:15 PMPhenotypic Drug Discovery Special Interest Group (SIG)
12:00 PM - 1:15 PMStandards Initiatives Special Interest Group (SIG)
- 1:30 PM - 3:30 PMEmerging Micro and Nanosystems for Pathogen DetectionMicro/Nano Technologies
1:30 PM - 2:00 PMA Rapid Antimicrobial Susceptibility Test Based on Single-cell Morphological Analysis Sung-Hoon Kwon – Dept. of Electrical and Computer Engineering, Seoul National University ### 184199###Speaker - Not Funded
2:00 PM - 2:30 PMNew Devices for the Detection and classification of Antibiotic-resistant Bacteria Shana Kelley – University of Toronto ### 184286###Speaker - Funded
2:30 PM - 3:00 PMRapid Detection of Antibiotic-resistant Bacteria by Droplet Digital Detection Dong-Ku Kang – University of California Irvine ### 119515###Speaker - Not Funded
3:00 PM - 3:30 PMShining Light on Middle Ear Diseases: Raman Spectral Signatures of Infection Rishikesh Pandey – Massachusetts Institute of Technology ### 184245###Speaker - Tony B. Awardee
- 1:30 PM - 3:30 PMHandling Complex Data: Phenotypic, High-Content, IntegrativeInformatics
1:30 PM - 2:00 PMIdentifying Druggable Cells: Automated Methods for High-content Single-cell Screening Tiffany J. Chen – Cytobank, Inc and Stanford University ### 184240###Speaker - Funded
2:00 PM - 2:30 PMIntegration of Machine Learning and Biomimetic Substrate for High-throughput Screening of Drug-Induced Cardiotoxicity in Human Cardiomyocytes Eugene Lee – University of California, Irvine ### 184265###Speaker - Tony B. Awardee
2:30 PM - 3:00 PMMachine-learning Methods for Screening, Recognition and Classification of Bacterial Colonies on the Basis of Elastic Light Scattering Characteristics Bartek Rajwa, PhD – Purdue University ### 184278###Speaker - Not Funded
3:00 PM - 3:30 PMPatient-Specific Drug Interaction Mapping in Personalized Immunosuppression Ali Zarrinpar – University of California, Los Angeles ### 184272###Speaker - Tony B. Awardee
- 1:30 PM - 3:30 PMScreening Automation: Modular Systems vs. Highly Integrated SystemsAutomation & High Throughput Technologies
1:30 PM - 2:00 PMAnalysis of Automated Robotic Platforms Used to Accommodate Various Screening Processes and Peripheral Operations Carleen Klumpp-Thomas – NCATS ### 184267###Speaker - Funded
2:00 PM - 2:30 PMThe Internet of Things and Bench-top Lab Automation Systems Bring You into the SmartLab of the Future - A Case Study of Ongoing Process Developments Felix Lenk – Dresden University of Technology, Institute of Food Technology and Bioprocess Engineering, Chair of Bioprocess Engineering ### 75064###Speaker - Not Funded
2:30 PM - 3:00 PMFrom Clone to Clinic: An Integrated Robotics and Informatics Platform for High Throughput in Vivo and in Vitro Biologics Screening and Development Nallakkan Arvindan – Five Prime Therapeutics ### 184281###Speaker - Not Funded
3:00 PM - 3:30 PMUltra-high Throughput Genotyping: A Novel Platform That Curtails Cross-contamination and Increases Data-quality J. Colin Cox, PhD – Genentech, Inc. ### 72748###Speaker - Not Funded
- 1:30 PM - 3:30 PMSecondary Screens, ADME-Tox, Removing Artifacts and Compound Profiling Assays in HTSAssay Development & Screening
1:30 PM - 2:00 PMPredicting the in Vivo Phospholipidosis-inducing Potential of Drugs by a Combined in Vitro High Content Screening and in Silico Modelling Approach Clive Dilworth – Cyprotex ### 184284###Speaker - Not Funded
2:00 PM - 2:30 PMDevelopment of a screen cascade to validate ULK 1 kinase inhibitors Barbara Saxty, PhD – MRC Technology ### 196708###Speaker - Not Funded
2:30 PM - 3:00 PM3D Networks of iPSC-derived Neurons and Glia for High-throughput Neurotoxicity Screening Remko van Vught – Mimetas ### 184228###Speaker - Not Funded
3:00 PM - 3:30 PMHuman iPSC-derived Cardiomyocytes: A Predictive, HTS-Scalable Tool for Comprehensive Cardiac Safety/Toxicity Assessment Gregory C. Luerman – Axiogenesis Inc ### 142473###Speaker - Not Funded
- 1:30 PM - 3:30 PMSuccessful Strategies for Difficult TargetsDrug Target Strategies
1:30 PM - 2:00 PMDrug-Target Residence Time: Target Engagement, Target Vulnerability and Predictions of in Vivo Drug Activity Peter Tonge – Stony Brook University ### 184297###Speaker - Funded
2:00 PM - 2:30 PMNon-equilibrium Profiling of Drug Candidates with kPCA: A Universal Homogeneous Assay for High-throughput Determination of Binding Kinetics Amaury E. Fernández-Montalván – Bayer Pharma AG, Lead Discovery Berlin ### 184229###Speaker - Not Funded
2:30 PM - 3:00 PMDiscovery of Novel Antagonists at the Protease Activates Receptor (PAR2) Receptor Through DNA Encoded Library Screening of a Thermostabilised Receptor Steve Rees – AstraZeneca ### 62461###Speaker - Not Funded
3:00 PM - 3:30 PMChemoproteomics Approaches for Target-based Screening of Large Compound Libraries in Cell Extracts and Live Cells Christina E. Rau – Cellzome GmbH, a GSK company ### 184243###Speaker - Not Funded
3:30 PM - 3:45 PMBeverage Break
3:45 PM - 4:45 PMKeynote: The Right Kind of Crazy: A True Story of Teamwork, Leadership and High Stakes Innovation Adam Diedrich Steltzner – Jet Propulsion Laboratory (JPL) ### 184064###Keynote Speaker
- 3:45 PM - 5:00 PMKeynote Session: Innovation Award Announcement & Closing RemarksKeynote
Time
Title